Article • Between good practice and financial pitfalls
Delivering molecular pathology at lower costs
Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.
Pathology
Article • Molecular meets digital
Single-cell multiplex imaging: a powerful tool for digital pathology
Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…
Article • Transformative technology
Debating the case for AI in pathology
Artificial Intelligence (AI) remains a divisive topic within the discipline of pathology with a range of opinions over its current value and applicability in clinical settings. While most experts agree that the technology will not replace pathologists, it might still spell bad news for those who do not embrace AI in their daily practice. On the other hand, reservations persist about whether…
News • Insights into tumor biology
Breast cancer: Exploring metastasis diversity
In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.
News • Single-cell metabolic profiling
Mass-spec and IMC give deep insights into tumors
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
Sponsored • Tissue-Tek Xpress® x120 Rapid Tissue Processor
Process tissue continuously, safely, and in a standardised way while speeding up your throughput
Sakura Finetek’s Tissue-Tek Xpress® x120 Rapid Tissue Processor is the only instrument on the market that allows for continuous, rapid processing of both biopsy and larger tissue, resulting in a streamlined histology workflow. Being part of Sakura’s SMART Automation concept, this tissue processing solution is designed to automate manual work and create a continuous flow throughout the lab.
News • Achieving and maintaining high service quality
QA in histopathology laboratories from pre- to post-analytic phase
Testing from histopathology laboratories is considered the gold standard for many diseases. To avoid errors that can significantly impact patient outcomes, an expert details on quality assurance (QA).
Article • Interdisciplinary senology
Mammography, ultrasound, MRI: which imaging modality at which time?
Interdisciplinary collaboration between gynaecologists, radiologists, pathologists and breast care nurses following a palpation finding makes a decisive contribution to the success of further breast cancer treatment. This was the consensus among the speakers at the Annual Congress of the German Society of Senology in Dresden. The experts provided clear explanations of which imaging is best for…
News • Color adjustment technique
More consistent histopathology slides for machine learning use
In a recent study, researchers proposed a novel technique to help make stained histopathological image datasets more useful for many emerging machine-learning-based classification systems.
News • Automated tissue analysis
Digital pathology: AI platform to improve lung cancer diagnosis
Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.
News • Tailored chatbot
Customized ChatGPT to advance digital pathology
New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.
News • Tumour infiltrating lymphocyte measurement
Breast cancer: AI tool predicts which DCIS cases become invasive
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
Article • Challenges and opportunities
Molecular pathology in Europe: in search of standardization
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
News • Infectious disease diagnostics
POCT for remote areas: Portable pathology passes the test
When point-of-care testing (POCT) models for diagnosing infectious disease are effective, the quality of pathology results can be equivalent to laboratory tests, new research shows.
Sponsored • Laser cassette printer
Leaping forward with laboratory workflow automation
Embark on a journey of unparalleled efficiency and precision with Sakura Finetek Europe's newest innovation in identification technology: the Tissue-Tek xPrint® LP Laser Cassette Printer.
News • Neuropathology
Technology offers new insights into pediatric brain tumors
A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.
Article • Pros and cons of diagnostic techniques
Liquid biopsy vs. tissue biopsy: Getting the best of both worlds
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
News • Three-dimensional tissue processing
Pathology performs leap into 3D with AI
Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.
News • Research on large foundation models
Reducing bias in pathology AI
A study highlights performance differences in computational pathology systems, depending on demographic profiles associated with histology images. The researchers also propose a way to fix this bias.
News • Pathology solutions provider
Jaap Stuut appointed as Sakura Finetek President
Sakura Finetek Europe has appointed Jaap Stuut as the President and General Manager. He will lead the company's EMEAI division in this role, shaping the its mission, vision, and long-term strategy.
News • New-found blood signatures
Multiple sclerosis: subtype discovery opens new ways for personalized therapy
Researchers discovered three distinct immunological endophenotypes of multiple sclerosis, defined by specific blood immune signatures. This opens new avenues for personalized treatment strategies.
Article • Interdisciplinary diagnostics
Crossing the radiology-pathology boundary
In diagnostics, there used to be a hard divide between radiology and pathology, where methods were largely considered incompatible with one another. However, to pave the way for next-generation diagnosis, Professor Regina Beets-Tan urged both sides to come out from their trenches and appreciate the synergies the fields have to offer. In her presentation at the European Congress of Radiology (ECR)…
Article • Improving quality and efficiency
Preparing for AI in clinical laboratories
Some year in this decade, AI tools will become ubiquitous within clinical laboratories. AI has the potential to increase the accuracy of laboratory testing and improve the quality and efficiency of operations and service of testing labs.
News • Interpretable machine learning system
AI to detect colorectal cancer from pathology slides
Researchers work on the first prototype that applies AI to colorectal diagnosis. The prototype achieved a diagnostic acuity of 93.44% and a sensitivity of 99.7% in the detection of high-risk lesions.
News • Histological transformation
How lung cancer can transform into another type
Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.
