News • Deep learning refinement
Colorectal cancer: AI tool improves diagnostic accuracy
Researchers from Finland have developed an artificial intelligence tool for automatic colorectal cancer tissue analysis that outperforms prior methods.
Pathology
News • Biomarker-based predictions
AI drives precision oncology for colorectal cancer
For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).
Article • Breast cancer diagnostics
Precision pathology: an AI-led alternative to molecular diagnostics
Experts have highlighted how precision pathology using Artificial Intelligence can provide an effective alternative to molecular diagnostics. This, say a team from the Karolinska Institutet (KI) in Stockholm, Sweden, can also offer multiple advantages within a clinical setting and support risk stratification.
News • Protein alterations in rare cancer
‘Rosetta stone’ of sarcoma research to help personalise treatment
An 'encyclopaedia' of protein alterations in soft tissue sarcomas could open the door to a new era of understanding and treatment for this group of rare cancers.
News • Women's health
Why obesity makes ovarian cancer more deadly
A new study led by researchers from the University of Notre Dame links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors.
News • Transforming medical diagnosis
Digital pathology: set to be a game changer in the medical industry
With the introduction of digital pathology, the University of Queensland and Sullivan Nicolaides Pathology aim to provide significantly improved tests in terms of cost, quality and speed.
News • Research into fat cells
Healthy adipocytes keep breast cancer at bay
Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer. According to the experts, adipocytes play a vital role here.
News • Methylation pattern analysis
cfSort: New tool could improve liquid biopsy
A research team at UCLA has made an important advancement to address one of the major challenges in cell-free DNA (cfDNA) testing, also known as liquid biopsy.
News • 3D visualisation and mixed reality
Is the future of autopsies digital?
From current mixed reality assistance, technological advances could soon make fully digital autopsies a reality. This could enhance efficiency and legal certainty, and also benefit training.
News • Molecular and immunofluorescence imaging
Orion: A new tool for diagnosing cancer
Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.
News • Sars-CoV-2 infection sequelae
From over 200 to 12 symptoms: Study sharpens definition of "Long Covid"
A study led by the National Institutes of Health’s RECOVER Initiative and supported by NYU Langone Health provides an expanded working definition of long Covid.
Article • Confirming initial positive findings
First-tier rapid serology testing for Lyme disease
Lyme disease, the most common tick-transmitted bacterial infection in the world, is challenging to diagnose. Initial early-stage symptoms may include skin rash, fever, headache, fatigue, swollen lymph nodes, and/or body and joint aches. However, these symptoms are also associated with many other diseases and medical conditions.
Sponsored • Fully automated, IVDR-compliant Tissue-Tek Genie®
Advanced tissue staining meets standardisation
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
News • Technology transition
Netherlands Cancer Institute switches to new digital pathology platform
The Netherlands Cancer Institute (NKI) will deploy a diagnostic platform from digital and computational pathology solutions provider Proscia, the company announced.
News • Neurodegeneration assessment
New blood test differentiates Alzheimer’s disease from other dementias
A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.
News • Specialized immune cells
γδ T cells carry potential for new cancer immunotherapies
Dutch scientists have discovered how specialized immune cells can detect and remove cancers that are ‘invisible’ to the conventional defense mechanisms of the immune system.
News • Patient-derived whole-tumor cell culture model
Breast cancer: New method finds the right therapy
Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.
News • Application in pathology
Endometrial cancer diagnostics: AI gives new insights
New research shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. This could improve diagnosis and treatment of uterine cancer.
News • Novel approach in pathology
Laser microbiopsy: a minimally invasive method to extract tissue samples
In a recent study, a US research team developed a revolutionary laser-based approach to perform microbiopsies. Their novel method could make biopsies faster, more cost-effective, and less harmful to the patient.
Automation
Tissue-Tek Genie Advanced Staining System – Sakura Finetek
The Tissue-Tek Genie Advanced Staining System is the first and only fully automated, true random access stainer for immunohistochemistry (IHC) and in situ hybridisation (ISH); allowing any IHC or ISH capsule or probe to be loaded at any time on any station.
Sponsored • TissueTek Genie System
Advanced staining can be beautifully simple when we standardise it
Imagine, one single standardising solution, enabling uncompromisingly fast results and providing you with the exact same predictable turnaround time.
News • CSCC study finds distinct subgroups
Cervical cancer: major new clue to understanding aggressiveness
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
Supervised learning approach
A new deep learning-based algorithm to predict relapse-free survival in papillary thyroid carcinoma
The tall cell variant (TCV) is an aggressive subtype of papillary thyroid carcinoma (PTC). Sebastian Stenman, researcher from the Institute for Molecular Medicine, and the Department of Pathology at the University of Helsinki, Finland, is developing and training a deep learning algorithm using supervised learning to detect and quantify the proportion of tall cells in PTC.
CNN applications in pathology
‘Deep learning can predict survival directly from histology in clear cell renal cell carcinoma’
Renal cell carcinoma is among the fifteen most common cancers worldwide. Dr Titus Brinker, from the German Cancer Research Center (DKFZ), looked at whether a convolutional neural network (CNN) can extract relevant image features from a typical H&E-stained slide to predict 5-year overall survival.
Article • AI provides prognostic information
Next-generation deep learning models predict cancer survival
Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…