News • Women's health
Why obesity makes ovarian cancer more deadly
A new study led by researchers from the University of Notre Dame links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors.
Pathology
News • Transforming medical diagnosis
Digital pathology: set to be a game changer in the medical industry
With the introduction of digital pathology, the University of Queensland and Sullivan Nicolaides Pathology aim to provide significantly improved tests in terms of cost, quality and speed.
News • Research into fat cells
Healthy adipocytes keep breast cancer at bay
Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer. According to the experts, adipocytes play a vital role here.
News • Methylation pattern analysis
cfSort: New tool could improve liquid biopsy
A research team at UCLA has made an important advancement to address one of the major challenges in cell-free DNA (cfDNA) testing, also known as liquid biopsy.
News • 3D visualisation and mixed reality
Is the future of autopsies digital?
From current mixed reality assistance, technological advances could soon make fully digital autopsies a reality. This could enhance efficiency and legal certainty, and also benefit training.
News • Molecular and immunofluorescence imaging
Orion: A new tool for diagnosing cancer
Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.
News • Sars-CoV-2 infection sequelae
From over 200 to 12 symptoms: Study sharpens definition of "Long Covid"
A study led by the National Institutes of Health’s RECOVER Initiative and supported by NYU Langone Health provides an expanded working definition of long Covid.
Article • Confirming initial positive findings
First-tier rapid serology testing for Lyme disease
Lyme disease, the most common tick-transmitted bacterial infection in the world, is challenging to diagnose. Initial early-stage symptoms may include skin rash, fever, headache, fatigue, swollen lymph nodes, and/or body and joint aches. However, these symptoms are also associated with many other diseases and medical conditions.
Sponsored • Fully automated, IVDR-compliant Tissue-Tek Genie®
Advanced tissue staining meets standardisation
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
News • Technology transition
Netherlands Cancer Institute switches to new digital pathology platform
The Netherlands Cancer Institute (NKI) will deploy a diagnostic platform from digital and computational pathology solutions provider Proscia, the company announced.
News • Neurodegeneration assessment
New blood test differentiates Alzheimer’s disease from other dementias
A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.
News • Specialized immune cells
γδ T cells carry potential for new cancer immunotherapies
Dutch scientists have discovered how specialized immune cells can detect and remove cancers that are ‘invisible’ to the conventional defense mechanisms of the immune system.
News • Patient-derived whole-tumor cell culture model
Breast cancer: New method finds the right therapy
Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.
News • Application in pathology
Endometrial cancer diagnostics: AI gives new insights
New research shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. This could improve diagnosis and treatment of uterine cancer.
News • Novel approach in pathology
Laser microbiopsy: a minimally invasive method to extract tissue samples
In a recent study, a US research team developed a revolutionary laser-based approach to perform microbiopsies. Their novel method could make biopsies faster, more cost-effective, and less harmful to the patient.
Automation
Tissue-Tek Genie Advanced Staining System – Sakura Finetek
The Tissue-Tek Genie Advanced Staining System is the first and only fully automated, true random access stainer for immunohistochemistry (IHC) and in situ hybridisation (ISH); allowing any IHC or ISH capsule or probe to be loaded at any time on any station.
Sponsored • TissueTek Genie System
Advanced staining can be beautifully simple when we standardise it
Imagine, one single standardising solution, enabling uncompromisingly fast results and providing you with the exact same predictable turnaround time.
News • CSCC study finds distinct subgroups
Cervical cancer: major new clue to understanding aggressiveness
Scientists have discovered that cervical cancer can be divided into 2 distinct molecular subgroups – one far more aggressive than the other – as part of the largest ‘omics’ study of its kind.
Article • AI provides prognostic information
Next-generation deep learning models predict cancer survival
Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…
Article • Patient care
Molecular Tumour Board for better decision-making
As more genomic alterations become targets for therapy, health institutions and hospitals are creating specialist Molecular Tumour Boards to support better decision-making for patient care. This evolving team, and its role, was highlighted in a presentation at the 34th European Congress of Pathology in Basel, Switzerland.
Supervised learning approach
A new deep learning-based algorithm to predict relapse-free survival in papillary thyroid carcinoma
The tall cell variant (TCV) is an aggressive subtype of papillary thyroid carcinoma (PTC). Sebastian Stenman, researcher from the Institute for Molecular Medicine, and the Department of Pathology at the University of Helsinki, Finland, is developing and training a deep learning algorithm using supervised learning to detect and quantify the proportion of tall cells in PTC.
Malignant tumour management
’Our machine learning model achieved 88.9% accuracy in predicting the sarcoma-specific survival rate’
Clinical management of soft tissue sarcoma is particularly challenging. Dr Sebastian Foersch, researcher at the Institute of Pathology at the University Medical Center in Mainz, Germany, has used a deep learning model for diagnosis and prognosis prediction of soft tissue sarcoma using conventional histopathology slides.
CNN applications in pathology
‘Deep learning can predict survival directly from histology in clear cell renal cell carcinoma’
Renal cell carcinoma is among the fifteen most common cancers worldwide. Dr Titus Brinker, from the German Cancer Research Center (DKFZ), looked at whether a convolutional neural network (CNN) can extract relevant image features from a typical H&E-stained slide to predict 5-year overall survival.
Article • Lab equipment
LABBook - Your guide to laboratory and pathology equipment in Europe
LABBook provides an overview of European laboratory systems. Whether you are about to set up a new lab or want to replace existing equipment, LABBook will help you make smart investment decisions to boost efficiency and productivity in your lab.
Sponsored • The 50 shades of brown
Sakura Finetek Europe enables optimal only Advanced Staining results
Imagine a new quality standard that improves the lives of patients and lab professionals in cancer care.
