Researchers at Leipzig University and Leipzig University Hospital (UKL) have discovered that tumour growth and tissue invasion by cancer cells can be predicted based on the ontogenetic distance between tissues.
Amid ever-growing demand for services, significant challenges face the pathology workforce in the years ahead but – there are also good opportunities. With advances in technology and the advent of artificial intelligence as a decision-making support tool, Professor Jo Martin, President Royal College of Pathologists (RCPath) in the UK, believes there remain opportunities for pathology to play a…
Pathology is embracing digitisation just as radiology did over 20 years ago and both specialties are looking at new ways to integrate each other in their workflows. AI could fuel this sparkling alliance, giving it further means to improve cancer treatment.
A team of researchers has developed a novel technology that could sensitively and accurately detect and classify cancer cells, as well as determine the disease aggressiveness from the least invasive biopsies. With this new technology called STAMP (Sequence-Topology Assembly for Multiplexed Profiling), comprehensive disease information can be obtained faster, at a much earlier stage of the…
Pathologic-radiologic correlation is already utilised in various settings as a tool to assess the interpretive performance of imaging studies and identify radiologic features corresponding to histologic findings. However, correlative assessment is currently limited mainly to the fields of research and quality assurance, and is generally not a routine element of the radiologist or pathologist…
Artificial Intelligence (AI) is destined for a significant role in assessing histology data but the key to developing the necessary algorithms lies in data quality – rather than the quantity, according to Professor Jens Rittscher. He also warns that we are some distance from seeing AI replacing human pathologists in this scenario, primarily because presently the risks of automated…
We talked to Dr Annika Blank, Consultant and Lean green belt, about eight-year experience with the concept and optimisation of processes, the implementation of digital pathology and a voice recognition system for patient management. "The biggest and most cost intensive step taken to optimise workflows was the refurbishment of our laboratory, which was completed in 2016. This allowed us to…
Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma. A research team from University Hospital Zurich and the University of Oxford have now developed a method to predict the molecular classification of colorectal cancer from digital pathology slides.
Image analysis of prostate cancer is a challenging area for clinicians. The disease shows a low mutation burden compared to melanoma and stomach cancer, for example, making morpho-molecular correlation more difficult, and there is often very low inflammation. With the role of tumour infiltrating lymphocytes in prostate cancer currently unclear – and with the advent of new approaches to prostate…
As reporting workload for pathology departments continues to rise rapidly, artificial Intelligence solutions are set to play an increasing role in daily practice. In many pathology departments the annual number of cases has risen by around 2-4% but the slides produced has doubled in the last decade. Histopathologist Professor David Snead identified this phenomenon within his own centre in the…
A new deep learning algorithm, which demonstrates the potential of artificial Intelligence (AI) to support pathologists, has been developed for PD-L1 scoring in tumour cells and immune cells in urothelial carcinoma samples. Speaking at the Digital Pathology and Artificial Intelligence Congress in London last December, Dr Michel Vandenberghe, from AstraZeneca, outlined how PD-L1 expression level…
Pathologists, radiologists, urologists and radiotherapy specialists sit at the core of the treatment pathway for the patient, working together as a cohesive unit. In an innovative 2019 ECR session in Vienna, the prostate unit from Ghent University Hospital in Belgium outlined how the team works to deliver the best clinical outcome for patients. Session chair Professor Geert M Villeirs of Ghent…
Bring your application into the digital world and combine the new Olympus EP50 camera with our wide range of microscopes. Add the accesoires you need and choose the kit that fits your requirements. The Olympus EP50 camera makes digital imaging of microscopy samples a fast and engaging experience and is ready to use in seconds. The EP50 camera adds sophisticated digital features to any microscope…
Digital pathology can gain huge benefits from rapid image search and the effective extraction of knowledge from large medical archives via artificial intelligence (AI). It facilitates identification of anatomical and pathological similarities, significantly enhances the clinical workflow, and ultimately paves the way for more informed diagnosis and better patient outcome. Effective archive…
Digital pathology, combined with the power of Artificial Intelligence (AI), is one of the most promising fields for the delivery of precision medicine. In the first keynote address for the 5th Digital Pathology & AI Congress (Europe) held in London last December, Professor of Pathology, Marilyn Bui, focused on how digital pathology is impacting on precision medicine. During her address,…
AI has made an extraordinary qualitative jump, particularly in machine learning. This can help quantify imaging data to tremendously advance both pathology and radiology. At a recent meeting in Valencia, delegates glimpsed what quantitative tools can bring to medical imaging, as leading Spanish researcher Ángel Alberich-Bayarri unveiled part of his work. The boom in companies and start-ups…
Efforts have been made to digitise pathology in the Netherlands, where the Dutch pathology network PALGA has run since 1990, connecting all of the Netherlands’ laboratories. Paul J van Diest, head of the pathology department at the Utrecht University Medical Centre, presented the brand new Dutch digital pathology platform during ECP 2018. Launched this year, this enables quicker, easier…
The European Society of Pathology (ESP) holds its European Congress of Pathology (ECP) at different venues annually. This year, in Spain, 3,448 delegates from 87 countries attended. There, ESP president Dina Tiniakos spoke about the increasing role of pathology in precision medicine including challenges linked to digitisation. ‘Precision medicine is the centre-point for cancer management, but…
Measuring tumour infiltrating lymphocytes (TILs) is gaining importance in immunotherapy, but other variables must also be considered to boost prognosis and prediction accuracy, a leading pathologist argued at EBCC 11 last March in Barcelona. When it comes to prognosis and prediction for immunotherapy, a potentially new variable is emerging – TILs – white blood cells that have left the blood…
Leeds Teaching Hospitals NHS Trust and the University of Leeds have announced a critical milestone in going digital, by scanning every glass slide they produce. The milestone represents a major step towards achieving faster and accurate diagnosis for cancer patients in the future. The Pathology Department, located in St. James’ Hospital in Leeds, is one of the largest in the UK processing over…
GrossPath – the special worktable designed to ensure a pollution free, laboratory-grade working environment for slicing and preparing histological slide preparations. Its compact design makes the GrossPath Special Worktable the perfect laboratory equipment, especially for small facilities. As a product of our ECOline range, this worktable has been designed with a special view to conserving…
Integrated healthcare provider Primary Health Care has joined forces with Siemens Healthineers to deploy more than 70 Atellica Solution immunoassay and clinical chemistry analyzers. This marks Siemens Healthineers largest contract for in vitro diagnostics testing in Australia, and one of its most robust sales of the Atellica Solution. The analyzers are integrated with Atellica Diagnostics IT…
Royal Philips has been leading two healthcare innovation projects that will receive government investment as part of major cross-sector collaborations with the NHS, academia and industry partners from the UK Government’s Industrial Strategy Challenge Fund, delivered through United Kingdom Research and Innovation (UKRI). A joint multi-million pound investment by government and industry partners,…
Scientists of the Helmholtz Centre for Infection Research (HZI) have now dissected the precise molecular mechanisms of WAVE complex activation, occurring in a process involving separable, independent steps.
Accelerate your workflow with the intelligent, high-resolution DP74 brightfield and fluorescence camera from Olympus. Histologists and pathologists face intense, rushed workloads where every minute counts. Experience enhanced efficiency with our next-generation camera. The DP74 creates a map of where you’ve been and can easily and rapidly lead you back to previous positions on the sample,…