Digital technology solutions create new opportunities in diagnosis and assessment of renal conditions. With whole slide imaging (WSI), improved workflow and better visualization, such technology already yields a ROI for hospitals and laboratories.
Professor Dina Tiniakos, from the National and Kapodistrian University of Athens, predicts that NASH (Non-alcohol related steatohepatitis) cases will soar worldwide by 2030, with 800,000 liver deaths, costing health economies billions of dollars.
Digitisation offers great opportunities in pathology to work more efficiently and faster. Used correctly, it reduces the workload for both pathologists and laboratory staff.
The damage caused by Covid-19 to the lungs’ smallest blood vessels has been intricately captured using high-energy X-rays emitted by a special type of particle accelerator. Scientists used a new imaging technology called Hierarchical Phase-Contrast Tomography (HiP-CT), to scan donated human organs, including lungs from a Covid-19 donor.
Mass spectrometry – a powerful tool for analysing the molecular composition of a tissue sample – is invaluable during cancer surgery. However, mass spectrometers are complex and unwieldy, and certainly a poor fit for an operating room (OR). To create a bridge between the lab and OR, Professor Livia S Eberlin, from Baylor College of Medicine, has developed a very special ‘pen’.
The impact of the coronavirus pandemic on lung cancer patient care across Europe, and the contribution lung pathologists, have led to a better understanding of Covid-19, as outlined during the 33rd European Congress of Pathology, Within ‘The lung pathologist in the Covid-19 pandemic’ session, speakers detailed how the pandemic has affected patients, diagnosis and clinical trials, yet also…
Post-mortem CT (PMCT) increasingly supports pathologists, radiologists and forensic investigators particularly in cases of gunshot fatalities, mass casualties, decomposed and concealed bodies, fire deaths, diving deaths, non-accidental injury cases, and road traffic deaths, in which CT can indicate a pattern of injuries. In Dublin this August, the post-mortem (autopsy) technique was discussed…
Researchers at Karolinska Institutet have developed an AI-based tool that improves the diagnosis of breast cancer tumours and the ability to predict the risk of recurrence. The greater diagnostic precision can lead to more personalised treatment for the large group of breast cancer patients with intermediate risk tumours. The results are published in the scientific journal Annals of Oncology.
Small aggregates of proteins known as Aβ oligomers are suspected as the main cause for the development of Alzheimer’s disease. However, it is not yet clear where and under what conditions these toxic aggregates form.
Molecular pathology company Xyall BV launches its Tissector High Throughput (HT) system for precision diagnostics. This is a world first – enabling high volume, molecular diagnostic laboratories to capitalize commercially on the company’s automated tissue dissection technology.
A researcher at the Technical University of Denmark (DTU) has developed a mathematical model for use in automated image analysis of tissue samples. The model provides the possibility for better and more similar cancer prognosis and treatment.
SpeeDx Pty, Ltd. and MolGen announced the signing of an agreement to collaborate on supply and distribution of clinical diagnostics products and instrumentation across Europe and Asia Pacific. The partnership links specimen handling, nucleic acid extraction, assay set-up, amplification, and results reporting in a seamless integration of the companies technologies. “This partnership capitalises…
Did you know that changing microscopy camera can make a real difference to your microscopy workflow? Packed full of smart features to make your imaging faster and easier, Olympus’ new DP23 and DP28 (4K) cameras enable streamlined, comfortable sample analyses at the monitor and easier, smoother conferencing. Get the most out of the monitor view and discover the many benefits of the DP23 and DP28…
Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that lead to different symptoms with different prognoses of the affected individuals. The study was published in Nature Medicine.
Skin swab samples analysed using mass spectrometry could be used to detect Covid-19 in patients, according to research conducted at the University of Surrey in the UK. Current Covid-19 testing is via a polymerase chain reaction (PCR) test, which involves taking a swab of the back of the throat and inside the nose, but the team from Surrey - working with Frimley NHS Trust and the Universities of…
Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes. It is faster and cheaper than a conventional blood count. To demonstrate the technique’s potential, the researchers used blood plasma collected from Covid-19 patients.…
Rapid tests, PCR tests, self-tests… there are many test options to determine contamination with Covid-19. In most this is done by inserting a cotton swab deep into the nose and/or throat to extract some mucus – unpleasant for adults and often a drama for children. Towards the end of 2020, a new system emerged to rule out a Covid-19 contamination. The electronic SpiroNose performs a…
Researchers at the Universitat Autònoma de Barcelona obtained a highly accurate recreation of human glioblastoma’s features using a novel 3D microscopy analysis. The study, published in the journal Acta Neuropathologica Communications, provides new information to help with the diagnose, by finding therapeutical targets and designing immunotherapeutical strategies.
Medical imaging IT and cybersecurity company Sectra has received an order for its digital pathology solution from Amsterdam UMC in the Netherlands. This follows a recently announced radiology imaging contract. With radiology and pathology in one joint solution, Amsterdam UMC will be able to conveniently share images and information between the two medical specialties, enabling efficient…
Germany’s lack of diagnostic ability led to significantly underestimation of its own as well as global Covid-19 infection levels during the first wave. Now, however, improved testing and diagnosis of the condition more realistically reveal nearer 20,000 new cases a day across the country, according to Professor Hendrik Streeck, one of the country’s leading virologists. Speaking at a virtual…
Experts have identified two distinct immunological and cellular profiles in the lungs of Covid-19 patients which they believe could help define treatment pathways. From some of the earliest Covid-19 autopsies conducted in Europe, Swiss-based researchers have performed integrative digital pathology and transcriptomic analyses of lung tissues of 16 coronavirus patients who died from respiratory…
In order to analyze tumors, they have to be cut into thin slices. Now, a new technology has been developed that makes pieces of the tumor visible in 3D without cutting them.
Research and innovation hub Imec announced that it has started developing a groundbreaking SARS-CoV-2 test. Unlike current approaches (using blood, saliva, or a nasopharyngeal swab), the new test will identify SARS-CoV-2 virus particles in a person’s exhaled breath. The solution promises the accurate identification of a contagious case in less than five minutes.
Xyall BV, a medtech innovator in molecular pathology, has entered into a multi-year, strategic partnership with Motic, a world leader in microscopy and digital pathology systems. Their goal is to develop an automated, high-precision table-top tumour tissue dissection solution for hospital-based molecular pathology laboratories.
As Artificial Intelligence continues to impact on the development of digital pathology, potential users are still slow to implement key enabling technologies to harness the benefits, according to Dr David McClintock, who will detail critical steps for pathology departments to transition practice from glass (analogue) to digital (whole slide imaging) and embrace AI, to the 6th Digital Pathology…