Microscopy

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Video • Multiphoton microscopy gives new insights

Microscopic behaviour of developing breast cells uncovered

An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before. This new protocol provides detailed instructions on how to capture hi-res movies of cell movement, division and cooperation, in hard-to-reach regions of breast tissue. The technology – called multiphoton microscopy – uses infrared lasers to illuminate…

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News • Brain tumour analysis

Glioblastoma '3D maps' help find new therapies

Researchers at the Universitat Autònoma de Barcelona obtained a highly accurate recreation of human glioblastoma’s features using a novel 3D microscopy analysis. The study, published in the journal Acta Neuropathologica Communications, provides new information to help with the diagnose, by finding therapeutical targets and designing immunotherapeutical strategies.

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News • New microscopy approach

A smartphone-based test for Covid-19

Researchers at the University of Arizona are developing a Covid-19 testing method that uses a smartphone microscope to analyze saliva samples and deliver results in about 10 minutes. The research team, led by biomedical engineering professor Jeong-Yeol Yoon, aims to combine the speed of existing nasal swab antigen tests with the high accuracy of nasal swab PCR, or polymerase chain reaction,…

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News • CARS & multiphoton microscopy

Multimodal imaging to detect cancerous cells faster and more accurately

Improving the detection of cancerous cells during surgery – this is the goal of the European research project CARMEN. The research institutes Laser Zentrum Hannover e.V. (LZH) from Germany and Multitel asbl from Belgium work together with companies from both countries, JenLab GmbH, Deltatec, and LaserSpec, to develop a novel, compact and multimodal imaging system. This could even allow the…

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News • "Enhance that"

New algorithm sharpens focus of cryo-electron microscopes

Scientists have developed a tool that improves the resolution and accuracy of powerful microscopes that are used to reveal insights into biology and medicine. In a study published in Nature Methods, a multi-institutional team led by Tom Terwilliger from the New Mexico Consortium and including researchers from Lawrence Berkeley National Laboratory (Berkeley Lab) demonstrates how a new computer…

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News • Microbiome study

Do microscope eyepieces pose an infection risk?

Light microscope for viewing microorganisms such as bacteria and fungi are commonly found in scientific laboratories. A research team from Furtwangen University, the University of Tübingen and Carl Zeiss Vision International GmbH, Aalen, examined more closely their role as potential vectors of infectious pathogens. „Very little was known about this until now," explains the head of the…

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News • Smart algorithm

Automated analysis of whole brain vasculature

Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Research Centre for Environmental Health and the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels – right down to the finest capillaries – including any pathological changes. So…

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News • Imaging the brain

Ultra-miniaturized endoscope produces HQ images

Johns Hopkins engineers have created a new lens-free ultra-miniaturized endoscope, the size of a few human hairs in width, that is less bulky and can produce higher quality images. Their findings were published in Science Advances. “Usually, you have sacrifice either size or image quality. We’ve been able to achieve both with our microendoscope,” says Mark Foster, an associate professor of…

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Sponsored • Raising the bar

A new ultra-compact microscopy camera

The MKC-X800 ultra-compact camera is a new addition to Ikegami’s range of medical imaging equipment, which, the firm reports, sets higher than ever standards of imaging quality to capture the precise colour and image detail of surgical operations. Measuring just 28x28x52mm WHD and weighing 100g, it can be mounted on a surgical microscope, lightweight support stand or boom. With its 4K-native…

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News • In focus

Universal algorithm set to boost microscopes

Scientists from EPFL have developed an algorithm that can determine whether a super-resolution microscope is operating at maximum resolution based on a single image. The method is compatible with all types of microscopes and could one day be a standard feature of automated models.

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Video • Collagen unter the microscope

Seeing the pattern beneath the skin

As the largest organ of the human body, our skin is astounding. It protects us from infection, endures radiation, senses temperature, and is flexible enough to withstand our everyday activities. What holds this all together is the protein we all know and love: collagen. In a paper published in Scientific Reports a team from Japan found for the first time that collagen in the skin is organized in…

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News • WLAN-capability

Turning microscopes in the classroom into a wireless imaging system

Today’s educational landscape is changing rapidly thanks to technological advances. Introducing wireless capabilities to science classrooms enables lecturers to teach and students to learn in an engaging digital environment that promotes teamwork. Equipped with a WLAN-capable Olympus EP50 camera, every microscope in a classroom becomes a wireless imaging system. Using its own WLAN signal*, the…

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Video • Photonics

Rapid tissue analysis: Laser light detects tumors

Cancer - this diagnosis affects almost every second German at some point in his life. It is the second most frequent cause of death in Germany. But the earlier the disease is diagnosed, the greater are the chances of surviving it. A team of researchers from Jena present a groundbreaking new method for the rapid, gentle and reliable detection of tumors with laser light at the leading trade fair…

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News • Ultra-thin and polished

Next-generation objectives push boundaries of microscopy

Olympus has broken down barriers to imaging quality with the launch of its next-generation objectives. The breakthrough polishing technique enables the company to produce ultra-thin lenses that overcome the traditional trade-off between numerical aperture (NA), flatness and chromatic correction – enabling all three parameters to be significantly improved. Olympus has harnessed this proprietary…

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Sponsored • Product of the Month

Make Your Application Digital – with the EP50 Stand-alone Network Camera

Bring your application into the digital world and combine the new Olympus EP50 camera with our wide range of microscopes. Add the accesoires you need and choose the kit that fits your requirements. The Olympus EP50 camera makes digital imaging of microscopy samples a fast and engaging experience and is ready to use in seconds. The EP50 camera adds sophisticated digital features to any microscope…

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News • Microscopy in the body

The next generation of endoscopy technology

Biotechnologists, physicists, and medical researchers at FAU have developed technology for microscopic imaging in living organisms. A miniaturised multi-photon microscope, which could be used in an endoscope in future, excites the body’s own molecules to illuminate and enables cells and tissue structures to be imaged without the use of synthetic contrast agents. The findings have now been…

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News • Non-invasive diagnostics

Detecting bladder cancer with atomic force microscopy

A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder. In the first successful use of atomic force microscopy (AFM) for clinical diagnostic purposes, the researchers have been able to identify signature features…

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Article • Smartphone detection

Spectrometry? There's an app for that!

Checking a lump for malignancy, finding out if food is fresh, just with your smartphone? It’s possible, according to Eindhoven University of Technology researchers in the Netherlands. Their recently presented spectrometer is small enough to insert into a smartphone. This device is not yet ready for use on a big scale, Professor Andrea Fiore, supervisor of the Eindhoven research team points out.…

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Sponsored • Product of the month

Olympus Color Cameras – Confidence in Your Images

Let your images tell the story with Olympus’ high-quality digital color cameras for microscopy in hospitals. With crisp, noise-free images and 4K UHD live viewing, the Olympus UC90 and SC180 brightfield cameras capture all the details you see through the oculars – enabling easy on-screen viewing or sharing in large-screen presentations.

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Sponsored • Product of the Month

Olympus BX46 microscope – Protecting operators with ergonomics

In microscopy, ergonomics is particularly important as long periods at the microscope put unusually specific constraints on posture. In certain roles, such as in pathology, microscopy forms a significant part of daily activities – sometimes taking up more than 50% of working hours. Protecting operators by preventing injuries is of utmost importance in these routine microscopy roles.

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Sponsored • Competition

Olympus Image of the Year – Celebrating art in science

Olympus’ Image of the Year Award for light microscopy in Europe recognizes the very best in life science imaging. Inspired by the beauty and breadth of images submitted for Image of the Year 2017, Olympus is now continuing its quest for the best light microscopy art in 2018. For the chance to win one of three prizes, applicants can submit life science light microscopy images to…

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