By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…
A team led by the Garvan Institute of Medical Research has revealed a new approach for classifying breast cancer subtypes based on their cell profile, which could help personalise treatments for patients. By analysing breast cancer biopsies from patients at Sydney hospitals, the researchers revealed more than 50 distinct cancer, immune and connective cell types and states, which could assign…
In an effort to promote access to professional breast imaging knowledge, the European Society of Radiology (ESR) now links to educational materials from DenseBreast-info.org as a resource for its members about the screening and risk implications of dense breast tissue.
A researcher at the Technical University of Denmark (DTU) has developed a mathematical model for use in automated image analysis of tissue samples. The model provides the possibility for better and more similar cancer prognosis and treatment.
The Covid-19 pandemic continues to impact people’s health across the world. This goes beyond the disease itself, as healthcare systems adapt how they provide services. Routine screening has been severely affected with screening programmes reduced or paused.
In a collaboration with the Faculty of Statistics at TU Dortmund and the University Medical Center in Mainz, a research team at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) has developed a test that can be used to predict the success of therapy for breast cancer. Breast cancer is one of the most common tumour diseases worldwide. One in eight women will…
The contribution of Artificial intelligence (AI) has great potential in breast imaging efficiency, Professor Linda Moy MD told attendees at the 2021 Society of Breast Imaging/American College of Radiology (SBI/ACR) Breast Imaging Symposium this April. AI models for breast imaging have focused mainly on the diagnostic classification and detection of breast cancer.
Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation – are completed more than 38 weeks from the time of diagnosis. The observational study, which included more than 28,000 breast cancer patients registered in the American National Cancer Database, is…
Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms. In a paper published in the cancer journal Annals of Oncology, researchers report that the test accurately detected…
In the emerging era of personalized medicine, risk-based breast cancer screening protocols may be better than the one-size-fits all approach. It’s time to consider adopting them, Jack Cuzick, Ph.D., said in the President’s Address of the 2021 Society of Breast Imaging/American College of Radiology Breast Imaging Symposium.
A breast cancer therapy that requires just one shot of radiotherapy is as effective as traditional radiotherapy, and avoids potential damage to nearby organs, according to a paper by UCL experts.
One of the negative impacts of the coronavirus pandemic has been the suspension or postponement of many cancer screening services. Each year, these services help prevent and detect the presence of cancer at an early stage; timely diagnosis and care are crucial in preventing the spread of cancer. The National Screening Observatory has confirmed this, reporting alarming statistics: during the first…
Medical technology company iCAD, Inc. announced that ProFound AI for 2D Mammography might notably reduce the risk of interval breast cancer, according to a new retrospective analysis. The aim of the study was to determine if adding AI to reading mammography as a supportive tool may help in decreasing the interval cancer rate in population-based organized mammography screening programs in Germany.
Electricity may slow – and in some cases, stop – the speed at which breast cancer cells spread through the body, a new study indicates. The research also found that electromagnetic fields might hinder the amount of breast cancer cells that spread. The findings, published recently in the journal Bioelectricity, suggest that electromagnetic fields might be a useful tool in fighting cancers that…
Researchers at TU Berlin and Charité – Universitätsmedizin Berlin as well as the University of Oslo have developed a new tissue-section analysis system for diagnosing breast cancer based on artificial intelligence (AI). Two further developments make this system unique: For the first time, morphological, molecular and histological data are integrated in a single analysis. Secondly, the system…
Digital breast tomosynthesis (DBT) increases detection of breast cancer in symptomatic women under the age of 60, especially in dense breasts. A large, multi-institutional study conducted in the United Kingdom comparing the sensitivity of full-field digital mammography (FFDM), DBT, and FFDM plus DBT supports findings of two similar published studies, both conducted in China in the same time frame.
The management of biopsied breast lesions that are diagnosed as abnormal but are not definitively malignant is challenging and controversial. Treatment ranges from diligent follow-up, with imaging and subsequent biopsy, to surgical excision. Researchers at the Medical University of Vienna (Medizinische Universität Wien), Austria, have developed and validated a software algorithm designed to…
The impact of Covid-19 has been devastating; countless lives lost, millions of infections worldwide, health systems overwhelmed and economies rapidly shrinking. Screening, such as for breast or cervical cancer, is an area particularly affected, with numerous appointments delayed.
A new deep learning system to help radiologists improve their workflow efficiency when reading high volumes of screening mammograms is being developed at Johns Hopkins University’s Radiology Artificial Intelligence Lab (RAIL) in Baltimore, MD. DeepCAT (Deep Computer-Aided Triage) is focused on workflow prioritization.
Implementation of artificial intelligence into Scotland’s national breast screening service is moving closer following an initial success with a trial project. While Scotland’s breast screening trial has delivered highs and lows, significant hurdles have been overcome in terms of approvals, governance and patient acceptance.
An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before. This new protocol provides detailed instructions on how to capture hi-res movies of cell movement, division and cooperation, in hard-to-reach regions of breast tissue. The technology – called multiphoton microscopy – uses infrared lasers to illuminate…
For many women, swollen lymph nodes are a red flag pointing to breast cancer – but may also be a normal immune reaction to a Covid-19 vaccination. In this Q&A, breast imaging experts address the most important facts on the topic.
Cancer ranks as a leading cause of death in every country in the world, and, for the first time, female breast cancer is the most commonly diagnosed cancer, overtaking lung cancer, according to a collaborative report, Global Cancer Statistics 2020, from the American Cancer Society (ACS) and the International Agency for Research on Cancer (IARC). Data show that 1 in 5 men and women worldwide…
One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research. “The results provide more justification and rationale for starting the clinical trial in May,” said first author John Mackey, professor and director of oncology clinical…
MRI is the most sensitive method to detect breast cancer. However, the current breast cancer guidelines for Europe, Germany and Austria, still only recommend it for certain indications: For early detection in high risk patients, for differentiation between scarring and recurrences after breast-conserving treatment and to detect cancers of unknown primary site. This is the theory. However, in…