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New EU project CORONET

Interfaces between the brain and electrical circuits in technical devices or computers open new perspectives for basic research and medical application, e.g., for therapeutic brain stimulation and neuroprosthetics. The new EU project CORONET will develop the technological and theoretical foundations for such future “bio-hybrid” interfaces between biological and artificial nervous tissues.

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Superantigens could be behind several illnesses

Superantigens, the toxins produced by staphylococcus bacteria, are more complex than previously believed, reveals a team of researchers from the University of Gothenburg in an article published today in the scientific journal Nature Communications. Their discovery shows that the body’s immune system can cause more illnesses than realised.

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Synapses recycle proteins for the release of neurotransmitters

Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, German neuroscientists have now discovered that neurons systematically recycle the protein components necessary for transmitter…

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Cancer stem cells

Cancer stem cells (CSCs) are the engine that drives tumour growth. They can not only reproduce themselves but also differentiate to form all the specialised cells found within a tumour. While chemotherapy and radiotherapy non-specifically target all rapidly dividing cells, there is increasing evidence that CSCs are more resistant to these treatments. Report: Karoline Laarmann

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1000 Genomes Project publishes analysis of completed pilot phase

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. In the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic…

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The potentiated value of MR-PET imaging

Even more precise diagnoses, even better process controls -- the future of MR-PET technology has dawned. The first commercial, full-body hybrid scanners are either waiting in the wings or already installed. But what does the introduction of the MR-PET really mean for clinical practice? Professor Heinz-Peter Schlemmer MD, Head of the Radiology Department at the German Cancer Research Centre in…

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Article • MRI

9-, 10- or even 11-Tesla – is more always better?

Advancing magnetic resonance imaging (MRI) up the Tesla scale may sound good, but will it produce the results and patient safety radiologists actually desire? Faced with the question: ‘How many Tesla should it be?’, Professor Siegfried Trattnig MD, head of the Centre of Excellence in high-field MRI at the University Clinic for Radiodiagnostics, Medical University of Vienna, and Austria’s…

The MIRACLE begins

Detection of circulating and disseminated tumour cells in blood is a promising method to diagnose cancer dissemination, or to follow up cancer patients during therapy. Today’s methods and involve time-consuming (more than a day) sample processing and cell isolation steps -- all labour intensive and expensive. A lab-on-chip that could integrate those processing steps would enable faster,…

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Using fruit flies to help understand cancer

Small and with a life cycle of just two weeks, fruit flies are seen by many as pests and a problem all year round. However, for nearly a century, the humble insect, officially known as Drosophila melanogaster, which measures no more than 3mm, has performed a vital role in genetics and developmental biology. Fruit flies are genetically diverse and easy to use in research, helping scientists in a…

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Protein highways keep tissues organized

Precise regulation of tissue architecture is critical for organ function. Single cells build up a tissue by communicating with their environment and with other cells, thereby receiving instructions on whether to divide, change shape or migrate. An interdisciplinary group of researchers from several Max Planck Institutes have now identified a mechanism by which skin cells organize their interior…

Multiple sclerosis: Quality of care should not depend on place of residence

MS experts, European policy-makers, professional and patients’ organisations at the European Health Forum Gastein (EHFG) today called for benchmark care provision across the EU and for governments and health services to provide improved access to specialized care for patients with multiple sclerosis. About 600 decision makers in the fields of health policy, research, science and from…

Chequerboard of infertility treatment in Europe

European patients are in many countries, in fact, limited in their individual choice of medically assisted reproduction (MAR) treatment, experts from the European Society of Human Reproduction and Embryology (ESHRE) stressed today at the European Health Forum Gastein (EHFG). The EHFG is the most important conference on health care policy in the EU. This year it has attracted about 600…

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Colder days raise the risk of more heart attacks

In the light of global climate change, the relations between weather and health are of increasing interest. A drop in the average temperature outside is linked to a higher risk of people having heart attacks, according to a new study published on bmj.com today. UK researchers found that each 1°C reduction in temperature on a single day is associated with around 200 extra heart attacks.

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46th EASD Annual Meeting

Professor Claes-Göran Östenson, chair of the Local Organising Committee of the 46th European Association for the Study of Diabetes annual meeting, will welcome visitors in this the bicentenary year of the renowned Nobel-prize giving Karolinska Institute. Since its foundation in 1965, the EASD annual meeting has become the world’s largest international annual conference on diabetes research,…

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Seeking the genetic basis of diabetes

Researchers have identified 12 new genes associated with Type 2 diabetes (T2D) that look set to improve the understanding of the processes underpinning the condition. The findings could also offer new biological pathways that can be explored as targets for new therapies to tackle T2D.

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A bright future for biobanks

Ten years ago, molecular biologist Dr Peter H J Riegman set up a unique bio-bank for medical research at the pathology department of Erasmus Medical Centre, Rotterdam, The Netherlands. The Erasmus MC Tissue Bank now holds 30,000 samples from about 15,000 patients. However, when Dr Riegman discusses his bio-bank with international colleagues they do not immediately associate it with a clinic or…

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Warning: Staff may fail to spot suicide risk

Previous research has indicated that the emergency department might be well-placed to pick up patients vulnerable to suicide. However, according to a small, new study carried out by researchers at Manchester University, although people who frequently present themselves at hospital emergency departments may be at high risk of suicide, emergency care staff may fail to spot their vulnerability.

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