Furin is responsible for activating certain proteins and is involved in the processing and maturation of viral and bacterial preproteins. Indeed, the strength of Furin activity has already been recognised, and used previously by scientists to propose broad anti-viral, anti-bacterial, and anti-cancer treatments. This study used the binding site of human Furin in molecular dynamics (MD) simulation.
Author of the study, Omotuyi Olaposi, a lecturer in Biochemistry at the Adekunle Ajasin University, Nigeria, explains that the experiment ‘may provide further insight to the design of novel drugs for Ebola virus disease treatment’.
The study can be read online.
Source: Press Release Taylor & Francis Journals