Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
Novel 3D imaging could comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease.
Overweight increases the risk of an imbalance in sugar metabolism and even diabetes – but the opposite is also true: insulin production deficits contribute to overweight, a new study shows.
Swiss researchers have demonstrated how sensors could help detect health problems in the elderly at an early stage. This could help seniors to live a self-determined life at home for longer.
A new study shows that women with a breast cancer diagnosis undergoing procedures for fertility preservation are not at increased risk of recurrence of the disease or disease-specific mortality.
A device with the appearance of a Wi-Fi router uses a neural network to discern the presence and severity of one of the fastest-growing neurological diseases in the world: Parkinson's.
A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.
A new understanding of the 'swallow-tail', an anatomical landmark in the brain, could pave the way for earlier detection of Parkinson's disease.
A team from Geneva has discovered a molecule that can identify the development of diabetes before the first symptoms appear.
A research team has created the first gel-based cartilage substitute that is even stronger and more durable than the real thing, offering a promising solution for patient suffering from knee pain.
New research shows that cell-cell signaling could play a key role in the thickening of arteries due to high blood pressure.
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
Researchers at McMaster University create device to replicate conditions in blood vessels after grafts.
Researchers identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches.
A comprehensive assessment of scientific literature has uncovered empirical evidence that more than 58% of human diseases caused by pathogens, such as dengue, hepatitis, pneumonia, malaria, Zika, have been aggravated by climatic hazards.
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
Functional ultrasound localization microscopy (fULM) captures the cerebral activity at the micron-scale, opening up major future clinical perspectives for the diagnosis of cerebrovascular pathologies.
Researchers have developed adeno-associated virus variants that target heart muscle cells and can thus be used for the precise treatment of heart diseases.
Researchers propose a new Covid-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies - a promising alternative for people with a weakened immune system.
Researchers have identified an enzyme that is a promising new therapeutic target to combat the dangerous bacterial disease melioidosis.
It is often believed that a close relationship between owners and their dogs can bring many mental health benefits to owners, but findings from a new study paint a more complicated picture.
Long Covid sufferers have experienced a wider set of symptoms than previously thought including hair loss and sexual dysfunction, new research has found.
Indwelling catheters through the urethra often cause bacterial infections. A newly discovered synthetic peptide is a promising treatment option, even against antibiotic-resistant pathogens.
A sensor identifies misfolded protein biomarkers in the blood. This offers a chance to detect Alzheimer's disease before any symptoms occur. Researchers intend to bring it to market maturity.
A spin-off from ETH Zürich has developed a magnetically steerable catheter for quick and safe stroke treatment that no longer requires surgeons to be on site.