News • Menopause research
Hot flashes: a hazard for the heart?
Not just uncomfortable, but hard on the heart: Accumulating research suggests a link between hot flashes during the menopause and cardiovascular disease risk in women.
Research
News • Model system shows tumor grwoth
Novel organoid model for pancreatic cancer
Researchers in Munich have developed a novel model system that can be used to precisely track the growth steps and three-dimensional arrangement of pancreatic cancer cells.
News • Disrupted neurogenesis
Covid-19 delirium: new study reveals possible brain mechanisms
Researchers have shown that when brain cells are directly exposed to blood taken from Covid-19 patients with delirium, there is an increase in cell death and a decrease in the generation of new brain cells.
News • Biomarker research
Alzheimer's: blood test detects beta-amyloid
Researchers from Japan have developed a method to detect build-up of amyloid β in the brain, a characteristic of Alzheimer’s disease, from biomarkers in blood samples.
News • Insights into stem cell behaviour
Breast cancer: new mechanism of drug resistance discovered
Scientists in Italy discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells. They also devised an experimental therapy to bypass or prevent this.
News • Neurological disease marker
Promising new radiotracer for demyelination
US researchers have developed a test to detect loss of myelin - a key contributor to many neurological diseases including multiple sclerosis, traumatic brain and spinal cord injuries, stroke, and dementia.
News • Organ transplantation
New treatment could improve donor lung availability
Researchers at Lund University in Sweden and Skåne University Hospital have conducted an animal study bringing hope that more donor lungs could be used in the future.
News • Diagnostic imaging reseach
How contrast agents disperse inside cells
A research team has investigated how contrast agents disperse inside cells. This could improve the assessment and further development of these agents and contribute to future medical diagnostics.
News • How cancer spreads
Cancer metastasis: Breakthrough to lead to better treatments
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
News • Drug delivery research
'Tunneling' capsule to enable oral insulin intake
A newly developed capsule that tunnels through mucus in the GI tract could be used to orally administer large protein drugs such as insulin.
News • Coronavirus mechanism discovered
Organ-on-a-chip reveals how SARS-CoV-2 invades blood vessels
A research group has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.
News • Assessing bone quality via blood sampling
New device for diagnosing bone fragility
A new device for diagnosing bone fragility invented by the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE) has been approved for marketing in the European Economic Area and Switzerland. The device is based on a new approach to assessing bone quality via blood sampling.
News • Rare but potentially serious complication
First cases of encephalomyelitis resulting from monkeypox virus
As the monkeypox outbreak continues to spread around the globe, a rare but potentially serious complication of the virus has been discovered.
News • Cancer research
Key function of important leukemia gene demystified
The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team now showed that EVI1's cancer causing effect relies on activating a single gene — the stem cell transcription factor ERG.
News • Hopeful study
A noninvasive way to diagnose endometriosis
Women can suffer for years with the debilitating pain and medical complications of endometriosis without a diagnosis. Now, researchers believe they may be able to diagnose the condition using just menstrual blood.
News • Alveolar rhabdomyosarcoma
Promising new treatment for deadly pediatric tumor
Alveolar rhabdomyosarcoma is a rare pediatric tumor. For more than 40 years there has not been any new development regarding treatment. Research led by Prof. Dr. Anton Henssen at Charité University Berlin has now identified a new therapeutic option, using a drug that is currently under investigation for other types of cancer.
Article • Cryotherapy substitute
The surprising applications of ice cream in healthcare
From treat to treatment: Polish researchers explore the medical benefits of ice cream – despite the semi-serious presentation, a topic with surprising relevance for patients undergoing chemotherapy.
News • Deep mutational scanning for SARS-CoV-2
Preparing rapid tests for future coronavirus variants
How can rapid antigen tests be adjusted to reliably detect future variants of SARS-CoV-2? A research team funded by the National Institutes of Health is currently working on finding an answer.
News • Devil in the details
Why healthcare researchers must be wary of misusing AI
An international team of researchers advises that strong care needs to be taken not to misuse or overuse machine learning (ML) in healthcare research, despite all of its benefits.
News • Lung adenocarcinoma
Therapeutic target against common lung cancer identified
A new study led by researchers in Barcelona has determined the protein TIMP-1 as a valuable biomarker for the progression of lung adenocarcinoma. The results open the door to new treatments.
News • Photocatalytic surface
A new plastic film that uses room lights to kill viruses
Researchers at Queen’s University Belfast have developed a new plastic film that can kill viruses that land on its surface with room light.
News • Blood-brain barrier simulation
Artificial brain vessels advance drug testing
German researchers present a novel method for testing chemical agents that could help in the development of drugs against neurodegenerative diseases such as Alzheimer's.
News • Desperate cancer cells
How tumors mutate their way out of a crisis (and become drug-resistant)
Researchers discovered that cancer cells mobilize a SOS response when they are desperate to resist anticancer drugs. The team also came up with an anti-SOS approach that blocked the mechanism in mice.
Article • Modelling systems for human biology
Organoid technology: new opportunities for drug discovery
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
News • In-depth view at neurodegeneration
New 3D imaging approach looks into earliest stages of Alzheimer's
Novel 3D imaging could comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease.