News • Molecular test for bacteria response
New method rapidly reveals antibiotic resistance
Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
Laboratory
News • Perilous PSA policy
Prostate cancer ‘test by request’ drives overdiagnosis, argue experts
Experts argue that shared decision policies between patients and their doctors have led to high rates of PSA testing and clear medical harm, with minimal benefit and inequity.
News • Accuracy gain
Bowel cancer: double testing for better detection
Scientists from the University of Edinburgh have found that the accuracy of detecting bowel cancer is increased to almost 100% by carrying out a common test twice rather than once.
Article • Confirming initial positive findings
First-tier rapid serology testing for Lyme disease
Lyme disease, the most common tick-transmitted bacterial infection in the world, is challenging to diagnose. Initial early-stage symptoms may include skin rash, fever, headache, fatigue, swollen lymph nodes, and/or body and joint aches. However, these symptoms are also associated with many other diseases and medical conditions.
Sponsored • Fully automated, IVDR-compliant Tissue-Tek Genie®
Advanced tissue staining meets standardisation
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
News • HIV & hepatitis detection
HIV, hepatitis B and hepatitis C can be detected from a single drop of blood, study shows
Data on a test that can detect HIV, hepatitis B and hepatitis C from a single drop of blood is being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases.
News • Promising biomarker found
Who will develop long Covid? It's in the blood
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.
News • Access to medical information
Bad news from test results? Patients still want to know right away
A recent survey of more than 8,000 patients found that users overwhelmingly supported receiving their test results immediately, even if their provider had not yet reviewed them.
News • Immunotherapy effectiveness
Sex differences in pancreatic cancer: researchers reveal possible explanation
For pancreatic cancer, the effect of immunotherapy is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this sex difference.
Sponsored • Laboratory information systems
Looking for new software solutions?
Are you looking for a new software solution for your laboratory? Laboratory information systems by Clinisys offer future-proof solutions you can rely on!
News • Drug discovery
New FDSS-GX: Hamamatsu presents high-performance kinetic plate imager
Hamamatsu Photonics announces the release of a new high-speed kinetic plate imager, the FDSS-GX, designed for kinetic cell-based assay development.
News • Promising results pave way for trial
A vaccine against allergic asthma: reseachers report new milestone
French scientists are developing and testing a new vaccine to combat allergic asthma. Their latest study results pave the way for the organization of a clinical trial.
Article • Cervix, vulva and vagina
More certainty with methylation tests for early detection of cancer
A second-generation lab test for early detection of cervical cancer is the most recent addition to Oncgnostics’ portfolio. In particular, the company’s solution will help women in countries with limited cancer screening. Moreover, new research on the early detection of vulval and vaginal cancer might soon enable the development of tests for these cancers.
Sponsored • Promising combination: AFP, AFP-L3, DCP and GALAD score
Enhanced early detection of liver cancer
Worldwide, about one million people are suffering from hepatocellular carcinoma (HCC). In Germany alone, there are 9,000 new patients each year, most of them men between 50 and 60 years. When liver cancer is detected early, the prognosis is excellent, says Professor Dr. Ali Canbay, Director of the Medical Clinic at the University Hospital/Knappschaftskrankenhaus Bochum. While, unfortunately,…
News • Model organisms evolved too far
How lab bacteria became 'estranged' from their real-life counterparts
A model organism used in laboratories for the past 100 years has evolved so extensively that it may no longer be fit for purpose, according to a new study on bacterial strain Escherichia coli K-12.
News • Rapid screening diagnostic
94% accuracy: new prostate cancer blood test beats PSA method
Researchers have developed a new blood test to detect prostate cancer which displays greater accuracy than the current prostate-specific antigen (PSA) method.
News • Infrastructure project
Improving lab accessibility for people with disabilities
Researchers at the University of East Anglia are launching a project to make laboratories more accessible for people with disabilities.
Video • Mini-bones from the lab
Toward a personalized approach of bone cancer research and therapy
Researchers generated human mini bones in the lab which mirror the composition and function of human bone - a step toward the development of future patient-tailored models of bone cancers and tumors.
News • Driving genes of AMR in focus
Tracking the global spread of antimicrobial resistance
An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.
News • High-sensitivity blood test
New cancer testing method to make regular monitoring affordable
Scientists from Singapore discovered a novel low-cost method of testing for cancers. The test sequences heated clinical samples to isolate cancer-specific signatures found in a patient’s blood.
Sponsored • Disease management
Multiplex Testing: A Solution to Manage Surge in Respiratory Illnesses as Concerns over “Multi-demic” Rise
Eunsin Bae, M.D. specializes in laboratory medicine and leads the Institute of Clinical Research at Seegene Inc. Her research focuses on microbiology, molecular biology, and hematology. Dr. Bae is currently working toward implementing a global clinical study and establishing an international network of clinical investigations.
News • Appeal for sustainability
POCT: Why the medical sector must tackle its single-use diagnostic waste
During the Covid-19 pandemic, the use of these single-use diagnostics, or point-of-care tests has exploded. This is having major environmental consequences, experts point out.
Article • Regulatory challenges for AI-based diagnostics
Further IVDR changes: a step in the right direction, but…
New changes made to the timetable for the In vitro Diagnostic Medical Device Regulation (IVDR) across Europe could have a significant impact on manufacturers and users, an expert points out. While the extension of the transition period was a welcome step, other changes which were hoped for remain painfully absent.
Automation
Tissue-Tek Genie Advanced Staining System – Sakura Finetek
The Tissue-Tek Genie Advanced Staining System is the first and only fully automated, true random access stainer for immunohistochemistry (IHC) and in situ hybridisation (ISH); allowing any IHC or ISH capsule or probe to be loaded at any time on any station.
Article • Tissue-engineered glioblastoma model
3D brain tumour in a dish to personalize cancer treatment
It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.