Laboratory

Article • Prediction for breast, ovarian, cervical, and endometrial carcinoma

New test detects four women’s cancers from cervical screening samples

What if a test analysing cervical cells from a gynaecological swab could be used to detect four different female cancers at an early stage and also predict cancer risk over a healthy woman's lifetime? Researchers at the EUTOPS Institute in Innsbruck, Austria, are developing tests to do just that for breast, ovarian, cervical, and endometrial cancer detection.

Automation reimagines laboratory diagnostics service

San Paolo Hospital in Savona, Italy, has upgraded its Corelab-related analytical equipment. In collaboration with Beckman Coulter, the San Paolo diagnostic laboratory has installed Beckman Coulter’s DxA 5000 Laboratory Automation System, an innovative, high-throughput automation system that rapidly increases test processing.

The potential of AI in routine blood testing

It’s widely known that more than 70% of today’s medical decisions involve the results of laboratory tests, but the insights clinicians derive from these tests today may only be scratching the surface of their potential.

Article • Lab equipment

LABBook - Your guide to laboratory and pathology equipment in Europe

LABBook provides an overview of European laboratory systems. Whether you are about to set up a new lab or want to replace existing equipment, LABBook will help you make smart investment decisions to boost efficiency and productivity in your lab.

Sakura Finetek Europe enables optimal only Advanced Staining results

Imagine a new quality standard that improves the lives of patients and lab professionals in cancer care.

News • Coronavirus mechanism discovered

Organ-on-a-chip reveals how SARS-CoV-2 invades blood vessels

A research group has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.

News • Deep mutational scanning for SARS-CoV-2

Preparing rapid tests for future coronavirus variants

How can rapid antigen tests be adjusted to reliably detect future variants of SARS-CoV-2? A research team funded by the National Institutes of Health is currently working on finding an answer.

News • Lung adenocarcinoma

Therapeutic target against common lung cancer identified

A new study led by researchers in Barcelona has determined the protein TIMP-1 as a valuable biomarker for the progression of lung adenocarcinoma. The results open the door to new treatments.

News • Conference attendance

New lab systems for virology showcased at ESCV 2022

Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.

News • Streptococcus pneumoniae

Technique helps discover whether bacteria are antibiotic resistant

A new study could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae, which cause meningitis, are resistant to antibiotics.

Article • Overheard at AACC

The complexities of drug testing in urine and hair

Urine screening tests using only immunoassays are the most common procedures used to identify drug abuse. They are inexpensive, automated, and produce rapid results. But they may generate false-positive or false-negative results, which vary based on the drug, drug class, and the assay used. Hair toxicology analysis is another form of drug testing which, unlike urine tests, enable analysis of drug…

Article • Modelling systems for human biology

Organoid technology: new opportunities for drug discovery

Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.

Article • Preventing clinical errors

Supporting transgender health in the clinical laboratory

Clinical laboratories need to be proactive to attract transgender patients for testing and to ensure that they are comfortable with the services provided. This issue is of great importance to the American Association for Clinical Chemistry (AACC), which conducted a scientific session on transgender health at its recent annual meeting in Chicago.

News • Osteoarthritis help

Lab-made cartilage gel outperforms real thing in knees

A research team has created the first gel-based cartilage substitute that is even stronger and more durable than the real thing, offering a promising solution for patient suffering from knee pain.

News • Blood sample

Paper test may predict Covid-19 immunity

The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.

News • Spit take

Portable diagnostic detects SARS-CoV-2 RNA and antibodies

The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.

News • Sebum analysis

Are skin swabs the future of Covid-19 testing?

Skin swabs are "surprisingly effective" at identifying Covid-19 infection, according to new research, offering a route to a non-invasive future for Covid-19 testing.

Rapid and robust PCR testing for infectious diseases at Innklinikum Altötting and Mühldorf

The Covid-19 pandemic has highlighted the importance of the fast and accurate diagnosis of infectious diseases in clinical settings. Harald Maier discusses the implementation of rapid molecular diagnostics in the central clinical diagnostics laboratory at Innklinikum Altötting and Mühldorf, highlighting how the use of PCR testing has benefitted the hospital during the Covid-19 pandemic.

News • Nanometer-scale imaging

Microscopy technique enables 3D super-resolution

Research team led by Göttingen University combine two techniques to achieve isotropic super-resolution imaging.

News • Nanochannels

Groundbreaking: Nanofluidic scattering microscopy

To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.

Article • Patient-based real-time approach

PBRTQC: improving quality control in the lab

Implementing patient-based real-time quality control (PBRTQC) protocols within the laboratory testing setting can offer benefits in terms of patient safety and reducing risks.

Veros™ COVID-19 test now available in Europe

Handheld, instrument-free test delivers lab-quality molecular results – 97.9% accuracy – in about 15 minutes, right at the point of care.

News • Infectious disease screening

Bronchial organoids and drug discovery applications advance Covid-19 research

A research group from Kyoto developed two in vitro models to study SARS-CoV-2, and showed that they can be used for drug screening for infectious diseases including Covid-19.

News • Biomarker from blood test

Lung cancer: Liquid biopsy accurately predicts immunotherapy response

A simple blood test could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure.

News • New treatment approach

'Self-destructing' parasite: The solution for drug-resistant malaria?

Over the last 50 years, malaria parasites have developed resistance to seven drugs, but a new way to identify future antimalarials holds promise.

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