Therapy

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News • Immunotherapy

apceth and University of Cologne to Join Forces

apceth announced a broad partnership with the Center for Molecular Medicine Cologne (CMMC), University of Cologne, to combine technologies and expertise, on the development of immunotherapies for solid tumors and haematological malignancies. The collaboration will start immediately and is based on combinations of Chimeric Antigen Receptor (CAR) T cells, developed at the laboratory of Prof Hinrich…

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Novel DNA repair mechanism brings new horizons

A group of researchers, lead by Vasily M. Studitsky, professor at the Lomonosov Moscow State University, discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment and prevention of neurodegenerative diseases. The article describing their discovery is published in AAAS' first open access online-only journal Science Advances.

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Article • UTI pathogen

Boosting the Body’s Natural Ability to Fight Urinary Tract Infections

Urinary tract infections (UTIs) are common, and widespread antibiotic resistance has led to urgent calls for new ways to combat them. Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that an experimental drug that stabilizes a protein called HIF-1alpha protects human bladder cells and mice against a major UTI…

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Article • Stroke treatment

Six international studies endorse thrombectomy

Results from six international randomised controlled studies conclusively and uniformly confirm, for the very first time, the effectiveness of thrombectomy in patients with acute, severe ischaemic strokes caused by a blood clot in one of the proximal cerebral arteries. The endovascular procedure is an add-on to conventional thrombolysis. EH reports from a German Stroke Society (DSG) press…

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Article • Orthopedics

Bioactive gel to treat knee injuries

Knee injuries are the bane of athletes everywhere, from professionals and college stars to weekend warriors. Current surgical options for repairing damaged cartilage caused by knee injuries are costly, can have complications, and often are not very effective in the long run. Even after surgery, cartilage degeneration can progress leading to painful arthritis. But a University of Iowa orthopedics…

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Article • Radiotherapy

Prostate: Free of cancer after five years

Results from a randomised controlled trial to compare the use of permanent radioactive implants (brachytherapy) with dose-escalated external beam radiotherapy in patients with prostate cancer show that the men who received brachytherapy were twice as likely to be cancer-free five years later. These results presented Professor James Morris, from the Department of Radiation Oncology, Vancouver…

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Article • Management II

Coming of age with a chronic disease

During the transition from child to adult many teens with chronic diseases somehow slip through the healthcare cracks between paediatric and adult medicine. Compliance deteriorates, regular check-ups are missed – an international problem, as many studies indicate. A promising programme, launched in Berlin, helps teens to manage this difficult change. Report: Bettina Döbereiner

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Article • Cardiology I

Chest pain units in Germany

The German care system for patients with acute and unspecific chest pain is unique in Europe. The closely knit and countrywide network of accredited Chest Pain Units (CPUs) ensures fast and targeted diagnosis of acute cardiac events. The German CPUs may soon serve as a blueprint for other European countries. The German Cardiac Society (DGK) has already accredited the first institutions – others…

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Article • Personalised medicine

Computerised tailor-made retinopathy therapy

Nowadays the concept of personalised medicine is usually applied to oncology. However, there are other clinical disciplines in which therapies tailored to the individual patient are within reach, viz. ophthalmology. In the researchers’ limelight is intravitreal drug delivery since the outcomes of injections into the vitreous differ from patient to patient. Ophthalmologists in Vienna, Austria,…

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News • Stroke

Effectiveness of treatment confirmed

A research paper published in the New England Journal of Medicine (NEJM) today confirms earlier findings that a procedure called endovascular therapy (ET) for ischemic stroke is the best treatment option for many patients by reducing the incidents of disability. This is the fourth research paper published this year that confirms the efficacy of the treatment.

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Article • Non-invasive Ventilation

Two in one

The recently launched Respironics V680 ventilator, from Philips Healthcare EMEA, was guided onto the market by Arne Cohrs, its Sales and Marketing Director of Therapeutic Care in Patient Care and Monitoring. We asked him about his department and the merits of non-invasive and invasive ventilators. Report: Chrissanthi Nikolakudi

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