News • Mechanopathology
'Dengue-on-a-chip' to study infection mechanisms
Due to the effects of climate change, dengue is spreading worldwide. Now, researchers have developed a 'dengue-on-a-chip' model that helps study the virus more effectively.
News • Pulsed infrared light to enhance diagnostics
Finding the ‘fingerprints’ of cancer
New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.
News • Study on Staphylococcus aureus
Understanding bacterial antiviral defenses to tackle antibiotic resistance
In a new study, researchers show that the emergence of antibiotic resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.
News • Targeting early versions
A 'head start' in the race against pancreatic cancer
Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.
News • Double Stokes polarimetric microscopy
New method to help accelerate cancer diagnosis
A new method to quickly and accurately analyze the structure of collagen in tissue shows promise to improve the diagnostics of cancer and other diseases.
Article • Digital pathology discussion panel
The AI tools pathologists want and need
The evolving role of AI tools in digital pathology was explored at an open discussion during the annual Digital Pathology and AI Congress in London with a high-level panel of practitioners looking at current and future technology options. The panel of pathologists, scientists and academics from Europe and the USA assessed the tools they currently use and are available to them, and those they…
News • Machine learning analysis
Breast cancer: AI predicts metastasis from recurrence
The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.
News • HBV point-of-care identification
Hepatitis B: rapid diagnostic test to halt mother-to-child transmission
A new rapid diagnostic test can identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This could help prevent mother-to-child transmission during childbirth.
Sponsored • Laboratory automation
Connect, automate and innovate your lab through SMART Automation
In today’s fast-paced healthcare landscape, efficiency and accuracy are essential in overcoming workload challenges. Pathology laboratories are under pressure to keep up with growing demands, all while ensuring standardised, consistent and high-quality results.
News • Electrochemical biosensing
Nanotube sensors enhance accuracy in continuous health monitoring
Researchers have succeeded in producing sensors from single-wall carbon nanotubes that are suitable for detecting even minute changes in specific substances in the body, such as female hormones.
News • Intrinsic electrical activity drives cancer progression
SCLC: Deciphering the unusual aggressiveness of small cell lung cancer
New research reveals that self-generated electrical activity of small cell lung cancer (SCLC) directly promotes tumor metastasis and progression. This may provide new avenues for future treatments.
News • Circulating tumor DNA analysis
Liquid biopsy helps reduce chemotherapy in colon cancer patients
For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.
Article • Detection of neurodegenerative condition
Developing blood biomarkers to diagnose Alzheimer’s disease
There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…
Article • Promising, but in need of further validation
Implementation challenges of blood biomarkers for Alzheimer’s disease
Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…
News • Deep and ensemble learning improve performance
New AI tool surpasses previous methods in colorectal cancer tissue analysis
Researchers developed an advanced AI tool for automatic analysis of colorectal cancer tissue slides. The new model outperformed all predecessors in the classification of tissue microscopy samples.
News • Aldosterone-producing adenomas
The surprising complexity of adrenal gland tumors
New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.
News • Reseach on neurofilament light chain proteins
ALS: Improving diagnosis and management with new blood test
A new blood test, using neurofilament light chainproteins as biomarker, could lead to better diagnosis and management of amyotrophic lateral sclerosis (ALS).
News • Cell-free tumor DNA analysis
Liquid biopsy to unlock breast cancer treatments
New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.
News • Detection of hereditary syndrome
IVDR certification for breast and ovarian cancer assays
MRC Holland recently announced that five SALSA MLPA assays for the detection of hereditary breast and ovarian cancer (HBOC) syndrome were recently CE-marked for in vitro diagnostic (IVD) use under the new In-Vitro Diagnostic Regulation EU 2017/746 (IVDR).
News • Alternative to diagnostic brain imaging
Exploring the potential of blood tests for dementia diagnosis
Molecular changes associated with brain inflammation and dementia can be detected in the blood. Researchers want to use this to establish blood tests as an alternative to more costly brain scans.
News • Multi-omics-based prediction
Pancreatic cancer: 'biomarker panel' brings hope for early detection
The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.
News • Age-related cellular and molecular changes
How aging breast tissue shapes breast cancer risk
Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.
News • Study explores impact
How brain trauma can trigger Alzheimer's disease
Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.
News • Potentiator of AMR emergence and expansion
Diabetes as a driver of antibiotic resistance
Microbiologists have just shown that people with diabetes are more likely to develop antibiotic-resistant strains of Staphylococcus aureus, a leading cause of AMR-associated infections and deaths.
News • Alteration of immune response
Multiple myeloma: dangerous diversity
When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.
