News • Methylation pattern analysis
cfSort: New tool could improve liquid biopsy
A research team at UCLA has made an important advancement to address one of the major challenges in cell-free DNA (cfDNA) testing, also known as liquid biopsy.
News • Molecular and immunofluorescence imaging
Orion: A new tool for diagnosing cancer
Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.
News • Mysterious mechanism solved
Researchers discover how bowel cancer 'blinds' the immune system
A mystery which has stumped bowel cancer researchers for decades, has been solved by scientists at the Cancer Research UK Beatson Institute and University of Glasgow.
News • Precision oncology
Genomic sequencing benefits only 5% of cancer patients
Genomic sequencing panels as part of personalised cancer treatment have been found to only benefit one in 20 patients they are currently used for, according to a study by CNIO.
Sponsored • Diagnostic informatics
Innovative solutions for constantly changing laboratory requirements
Today, a large part of all further medical treatments is based on the results of laboratory analyses. The demand for complex test procedures remains high and the challenges for laboratories are growing.
Article • Cancer patients at risk
Blood test detects risk of neurotoxicity from CAR T-cell therapy
Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…
News • Beyond polygenic risk scores
Adding blood biomarkers to genomics to better predict common disease risk
New research suggests that combining blood biomarkers with genomic information more accurately, cost-effectively predicts the risk of developing diseases.
News • MCED for 50+ cancer types
Multi-cancer blood test shows real promise
A trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms.
News • Chronic myeloid leukaemia
CML therapy response predicted by AI "crystal ball"
AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.
News • Prostate cancer detection
Personalized PSA screening may improve accuracy
The accuracy of prostate-specific antigen (PSA) screening can be improved by including genetic factors that cause changes in PSA levels not associated with cancer, according to a multi-center study.
Sponsored • Safe blood collection products and value-based care
Protecting patients and healthcare workers
In the last decade, regional and global health organizations have pushed for making safety a central pillar of procurement, with a directive that cost should not be a barrier. The crucial question is: How easy is that to implement? How can a confident decision be reached that protects patients and healthcare workers without straining costs?
News • Sars-CoV-2 infection sequelae
From over 200 to 12 symptoms: Study sharpens definition of "Long Covid"
A study led by the National Institutes of Health’s RECOVER Initiative and supported by NYU Langone Health provides an expanded working definition of long Covid.
News • Circulating biomarkers
Blood tests shows brain impact of neurosurgery
Damage to the brains of patients operated on for brain tumors may be assessed by measuring biomarkers in the blood pre- and postoperatively, a new study from the University of Gothenburg shows.
News • Molecular test for bacteria response
New method rapidly reveals antibiotic resistance
Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
News • Perilous PSA policy
Prostate cancer ‘test by request’ drives overdiagnosis, argue experts
Experts argue that shared decision policies between patients and their doctors have led to high rates of PSA testing and clear medical harm, with minimal benefit and inequity.
News • Role of EBV in MS progression
New study explains how Epstein-Barr virus causes multiple sclerosis
Researchers at Karolinska Institutet have found further evidence for how the Epstein-Barr virus (EBV) can trigger multiple sclerosis (MS) or drive disease progression.
News • Accuracy gain
Bowel cancer: double testing for better detection
Scientists from the University of Edinburgh have found that the accuracy of detecting bowel cancer is increased to almost 100% by carrying out a common test twice rather than once.
News • HSNCC treatment stratification
Head and neck cancer: using organoids for personalized therapy
Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).
News • Booster shot frequency
Covid-19: Vaccination immunity wears off faster in obese people, study finds
Protection offered by Covid-19 vaccination declines more rapidly in people with severe obesity than in those with normal weight, scientists at the Universities of Cambridge and Edinburgh have found.
News • Infection microbiology
Researchers discover a potential cause of Parkinson’s disease
Researchers at the University of Helsinki have demonstrated that certain strains of Desulfovibrio bacteria are the likely cause of Parkinson’s disease in most cases.
Article • Confirming initial positive findings
First-tier rapid serology testing for Lyme disease
Lyme disease, the most common tick-transmitted bacterial infection in the world, is challenging to diagnose. Initial early-stage symptoms may include skin rash, fever, headache, fatigue, swollen lymph nodes, and/or body and joint aches. However, these symptoms are also associated with many other diseases and medical conditions.
Sponsored • Fully automated, IVDR-compliant Tissue-Tek Genie®
Advanced tissue staining meets standardisation
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
News • HIV & hepatitis detection
HIV, hepatitis B and hepatitis C can be detected from a single drop of blood, study shows
Data on a test that can detect HIV, hepatitis B and hepatitis C from a single drop of blood is being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases.
News • Prevention of blood cancer
Research identifies new target that may prevent blood cancer
An international coalition of biomedical researchers has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.
News • Promising biomarker found
Who will develop long Covid? It's in the blood
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.