Article • Awareness
Focus on cancer
From solid tumors to metastatic carcinomas and leukemia: cancer is among the most common causes of death. Keep reading for latest developments in early detection, staging, therapy and research.
Cancer
News • Novel therapy approach
MRI-guided magnetic seeds to kill cancer with heat
Scientists at University College London have developed a novel cancer therapy that uses an MRI scanner to guide a magnetic seed through the brain to heat and destroy tumours.
News • Brachytherapy side-effects
Countering skin damage from cancer radiation therapy with light
Light therapy may accelerate the healing of skin damage from radiation therapy by up to 50%, according to a recent University at Buffalo-led study.
News • BRCA and prostate, pancreatic cancers
Faulty 'breast cancer gene' BRCA also dangerous for men
Faulty versions of the BRCA1 and BRCA2 genes are well known to increase the risk of breast and ovarian cancer. Now, they have been linked to several other cancers, including those that affect men.
Article • Multi-disciplinary approach
Nurturing integrated diagnostics in oncology
Under the roof of integrated diagnostics, radiology, laboratory medicine and pathology are forming a powerful alliance. Hedvig Hricak, MD, PhD, explains the potential for cancer patients and details the role of radiologists within the construct.
News • Without causing neurological damage
Injections of zika virus destroys brain tumors
In both the mice and organoids, cytokines suppressed tumor growth after treatment, and defense cells migrated to the brain region affected by the tumor, alerting the immune system to its existence.
Article • Cancer mortality study
Does ethnicity affect brain tumour survival?
New research has pinpointed ethnicity as a potential factor in brain tumour survival. A UK study showed that white British people who have been diagnosed with a malignant primary brain tumour appear to have an increased one-year mortality than patients from at least four other ethnic groups.
News • Oncology
New blood test identifies if a patient has cancer
Researchers outline a new minimally invasive and inexpensive blood test that can identify cancer in patients with non-specific symptoms and whether these cancers have metastasised in the body.
Article • Precision medicine
Liquid biopsy: the ‘next frontier’ for cancer detection?
Mark Nicholls reports from the National Cancer Research Institute (NCRI) virtual Festival, with four expert speakers discussing the role of liquid biopsy in cancer detection.
News • Impaired proliferation and induced cell death
Newfound mechanism could stop cancer cells in their tracks
Researchers have identified a mechanism that impairs the proliferation of cancer cells and induces their death without affecting healthy cells. This could lead to improved cancer treatment.
News • Adversarial attacks
Fake images can fool cancer-spotting AI and human experts
Artificial intelligence (AI) models that evaluate medical images have potential to speed up and improve accuracy of cancer diagnoses, but they may also be vulnerable to cyberattacks.
News • Chemotherapy approach
New receptor insights might leave cancer bitter
Bitter taste receptors do not only support humans in tasting. They are also found on cancer cells. A team led by Veronika Somoza from the Faculty of Chemistry at the University of Vienna and the German Leibniz Institute for Food Systems Biology at the Technical University of Munich has investigated the role they play there. For this purpose, the scientists compiled and evaluated extensive…
News • Relapse research
Multiple myeloma: Tracking down resistant cancer cells
In multiple myeloma, a cancer of the bone marrow, relapse almost always occurs after treatment. Initially, most patients respond well to therapy. However, as the disease progresses, resistant cancer cells spread in the bone marrow, with fatal consequences for the patients. Scientists at the German Cancer Research Center (DKFZ), Heidelberg University Hospital (UKHD) and the National Center for…
Article • Cancer imaging
PET/MRI offers significant patient benefits
PET/MRI is offering new imaging opportunities for cancer patients at various points along the care pathway with its ability to assess different biological processes and its increased specificity.
Interview • Hybrid imaging
‘We need to drive standardisation in scanning’
Professor Regina Beets-Tan, President of the European Society of Radiology (ESR), looks on possible future developments in cancer imaging. AI is very promising in this regard, 'However, it has proven to be a problem that the data with which the artificial intelligence is fed must be very homogeneous,' the expert observes.
Article • Focused ultrasound
Histotripsy: fighting tumors with microbubbles
Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases. In this Medica-tradefair.com interview, Prof. Maciej Pech talks about testing cavitation events generated during histotripsy, explains the process, and reveals its advantages.
News • Cancer research
How to break through a tumor's protective shield
The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don’t eat me" signal, which tells the immune cells to stand back. Tumor cells exploit this CD47-based protection strategy for evading the immune system, by increasing presentation of CD47 on their cell…
Article • Mass spectrometry goes handheld
A pen to pin down the fringes of cancer
Mass spectrometry – a powerful tool for analysing the molecular composition of a tissue sample – is invaluable during cancer surgery. However, mass spectrometers are complex and unwieldy, and certainly a poor fit for an operating room (OR). To create a bridge between the lab and OR, Professor Livia S Eberlin, from Baylor College of Medicine, has developed a very special ‘pen’.
News • Ductal adenocarcinoma
Pancreatic cancer ‘priming’ may make chemotherapy more effective
A new approach to ‘prime’ the tumour environment may improve how effective chemotherapy is for pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer. In preclinical models, a team at the Garvan Institute of Medical Research could enhance the tumours’ response to chemotherapy by reducing the stiffness and density of the connective tissue known as the stroma,…
News • Promising approach
New nanoparticles suppress resistance to cancer immunotherapy
Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to an immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.
News • Enhancing T cell response
New targets for cancer vaccines identified
Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body’s own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.
News • DNA damage causes AML
Cancer chemotherapy side-effects on blood cell development
By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…
News • Combined chemotherapy
Pancreatic cancer: New treatment promising for older patients
Pancreatic cancer is a disease of the elderly: the average age of patients is 72. In Austria, about 1,600 people are diagnosed each year. Since pancreatic cancer has no specific symptoms, it is not usually diagnosed until the tumor is locally advanced or has already metastasized. Once the tumor has metastasized, it is usually no longer treatable by surgery or radiotherapy. In addition, the drug…
News • Patient response testing
New method predicts which cancer therapies work (and which don't)
A new technology that can study which therapies will work on patients with solid cancerous tumours has been developed by scientists at University College London (UCL). Researchers say the tool, which can rapidly test tumorous tissue against different treatments, such as chemotherapy, immunotherapy or radiotherapy, could be used by clinicians to pinpoint the best therapy for a particular patient.
News • Understanding oncogenesis
How normal cells turn into liver cancer cells
Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients. Previous studies have achieved this only by using powerful viral factors that are not common in human cancers. Since many human cancer types still lack specific diagnostic…
