News • New imaging method
Delayed fluorescence for effective surgical tumor removal
Researchers propose a new approach to identify cancerous tissue for surgical removal, based on real-time imaging of tissue oxygen concentration.
Cancer
News • Prevention measure scrutinised
Colorectal cancer: colonoscopy screening not as effective as previously believed
A randomized study shows colonoscopy screening reduces the risk of colorectal cancer by 18 percent. The reduction is much smaller than experts previously assumed.
News • Model system shows tumor grwoth
Novel organoid model for pancreatic cancer
Researchers in Munich have developed a novel model system that can be used to precisely track the growth steps and three-dimensional arrangement of pancreatic cancer cells.
News • Insights into stem cell behaviour
Breast cancer: new mechanism of drug resistance discovered
Scientists in Italy discovered a new drug-resistance mechanism in breast cancer that leads to the formation of cancer stem cells. They also devised an experimental therapy to bypass or prevent this.
News • How cancer spreads
Cancer metastasis: Breakthrough to lead to better treatments
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
News • Cancer research
Key function of important leukemia gene demystified
The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team now showed that EVI1's cancer causing effect relies on activating a single gene — the stem cell transcription factor ERG.
Article • Patient front and centre
One-Stop Clinic: diagnosis and treatment in one day, on one site, by one team
Cancer – one word that turns the patients’ world upside down. In addition to uncertainty and fear, they often face an unnerving series of exams and treatments. With its new One-Stop Clinic concept, GE Healthcare now wants to help make this journey as smooth as possible. At a single location, in an environment designed for comfort, the patients undergo all necessary steps within a short period…
News • Alveolar rhabdomyosarcoma
Promising new treatment for deadly pediatric tumor
Alveolar rhabdomyosarcoma is a rare pediatric tumor. For more than 40 years there has not been any new development regarding treatment. Research led by Prof. Dr. Anton Henssen at Charité University Berlin has now identified a new therapeutic option, using a drug that is currently under investigation for other types of cancer.
News • Lung adenocarcinoma
Therapeutic target against common lung cancer identified
A new study led by researchers in Barcelona has determined the protein TIMP-1 as a valuable biomarker for the progression of lung adenocarcinoma. The results open the door to new treatments.
Article • Interpreter of maladies
Will AI help realize the promise of precision medicine?
Machine learning and artificial intelligence (AI) have the potential to transform cancer treatment management worldwide. Their ability to rapidly analyse and integrate routinely acquired diverse data will improve the accuracy and effectiveness of precision medical treatments.
News • Precision oncology
What's new in cancer therapy?
Researchers from the University of Bern and Inselspital provide an overview of the latest technologies in precision oncology. Translating these into clinical application is still a major challenge.
News • Desperate cancer cells
How tumors mutate their way out of a crisis (and become drug-resistant)
Researchers discovered that cancer cells mobilize a SOS response when they are desperate to resist anticancer drugs. The team also came up with an anti-SOS approach that blocked the mechanism in mice.
Article • Modelling systems for human biology
Organoid technology: new opportunities for drug discovery
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
News • Impact of body constitution
Breast cancer: Tumour environment can affect prognosis
The interplay between the patient’s BMI, tumour size and cancer-specific proteins is of importance for the prognosis of breast cancer, a study from Sweden shows.
News • High-glade glioma research
Understanding why deadly brain cancer comes back
A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.
News • Tumor identification in CUP patients
Cancer of unknown primary: comprehensive molecular analysis can improve therapy
A considerable proportion of patients suffering from cancer of unknown primary (CUP) could benefit from comprehensive molecular analysis and molecularly-informed targeted therapies.
Video • Clonal somatic mutations
How does cancer grow? Genetic mapping gives new insight
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
News • Live bacterial therapeutics
Engineering the microbiome to potentially cure disease
Development of effective live bacterial therapeutics may depend more on using and re-introducing native microbes that can stick around than how the microbes are modified.
News • Throat surgery
After laryngectomy: AI screens voice pathologies
Striving to improve the patient’s quality of life after laryngectomy, researchers conducted a study, during which they searched for pathologies in patients’ voices using artificial intelligence (AI).
News • Liquid biopsy for early detection of brain tumours
Glioblastoma: Mathematical modelling could lead to simple blood test
The development of a simple blood test for glioblastomas could mean earlier diagnosis and more effective and personalised treatment options against the most common type of malignant brain cancer.
News • Determining aggressiveness
New discovery improves prostate cancer prognosis
Researchers in Sweden have now discovered a faster and easier way to determine who has an aggressive form of prostate cancer, and who has not.
News • Identification of treatment barriers
Immunotherapy: The right environment for fighting cancer
Cancer immunotherapy is a successful treatment form in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers found.
Article • Diversity, transparency, flexibility
Building trustworthy AI systems for cancer imaging
Building artificial intelligence (AI) tools that clinicians and patients can trust, and easily use and understand, are core to the technology being successfully deployed in healthcare settings.
Article • Multiparametric ultrasound
Experts assess usefulness of MPUS in the diagnostic conundrum
Multiparametric ultrasound (MPUS) has proven its value in the abdomen – now, the technique is increasingly moving towards peripheral areas such as breast and testis imaging, experts showed in a dedicated session at ECR 2022.
News • Better outcomes, fewer costs
Experts propose less invasive bowel cancer treatment approach
New research suggests that providing a break in treatment to patients with advanced bowel cancer could not only benefit a patient’s quality of life but could also help reduce costs.
