News • Histopathology
Introduction of new advanced staining system
Histopathology company Sakura Finetek Europe announces the launch of its newest solution Tissue-Tek Genie, an advanced staining system, entering a new market.
Sponsored • Art or science?
Advanced staining – Getting the optimal slide
Advanced staining evolved with growing complexity, resulting in many variations and combinations to get the right staining quality. It felt the flexibility brings you total control, but actually what we see is the introduction of multiple variables. This endless tweaking has taken its toll.
Article • Modelling systems for human biology
Organoid technology: new opportunities for drug discovery
Two-dimensional (2D) cultured cell lines and animal models have been the principal research tools for the past decade, but have several shortcomings. Three-dimensional cell cultures, or organoids, show great promise here.
Article • Overheard at AACC
The complexities of drug testing in urine and hair
Urine screening tests using only immunoassays are the most common procedures used to identify drug abuse. They are inexpensive, automated, and produce rapid results. But they may generate false-positive or false-negative results, which vary based on the drug, drug class, and the assay used. Hair toxicology analysis is another form of drug testing which, unlike urine tests, enable analysis of drug…
News • High-glade glioma research
Understanding why deadly brain cancer comes back
A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.
News • Tumor identification in CUP patients
Cancer of unknown primary: comprehensive molecular analysis can improve therapy
A considerable proportion of patients suffering from cancer of unknown primary (CUP) could benefit from comprehensive molecular analysis and molecularly-informed targeted therapies.
News • Neurological and psychiatric complications
Increased risk of 'brain fog' and other disorders two years after Covid-19 infection
New diagnoses of disorders including psychosis, dementia, seizures and ‘brain fog’ remain commoner two years after Covid-19 than after other respiratory infections, new research finds.
Article • Preventing clinical errors
Supporting transgender health in the clinical laboratory
Clinical laboratories need to be proactive to attract transgender patients for testing and to ensure that they are comfortable with the services provided. This issue is of great importance to the American Association for Clinical Chemistry (AACC), which conducted a scientific session on transgender health at its recent annual meeting in Chicago.
News • Early clues in the panceas
Detecting diabetes before first symptoms appear
A team from Geneva has discovered a molecule that can identify the development of diabetes before the first symptoms appear.
Video • Clonal somatic mutations
How does cancer grow? Genetic mapping gives new insight
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
News • Blood sample
Paper test may predict Covid-19 immunity
The new test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection.
News • Spit take
Portable diagnostic detects SARS-CoV-2 RNA and antibodies
The prototype device combines eRapid and SHERLOCK technologies into a single, postcard-sized system that can simultaneously detect the presence of both SARS-CoV-2 RNA and antibodies in a patient’s saliva.
News • Cardiomyopathy research
Genetic defects can cause heart failure
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
News • Liquid biopsy for early detection of brain tumours
Glioblastoma: Mathematical modelling could lead to simple blood test
The development of a simple blood test for glioblastomas could mean earlier diagnosis and more effective and personalised treatment options against the most common type of malignant brain cancer.
Article • Outbreak prevention and management efforts
Infectious diseases: new challenges for EU monitoring
Avian flu, MERS, Covid-19, monkeypox: outbreaks of infectious diseases are getting more common in Europe. As a result, the EU must adapt its surveillance strategies and introduce more data-driven, interdisciplinary countermeasues.
News • Rare but dangerous infectious disease
New target to combat Melioidosis
Researchers have identified an enzyme that is a promising new therapeutic target to combat the dangerous bacterial disease melioidosis.
News • Sebum analysis
Are skin swabs the future of Covid-19 testing?
Skin swabs are "surprisingly effective" at identifying Covid-19 infection, according to new research, offering a route to a non-invasive future for Covid-19 testing.
News • Determining aggressiveness
New discovery improves prostate cancer prognosis
Researchers in Sweden have now discovered a faster and easier way to determine who has an aggressive form of prostate cancer, and who has not.
Sponsored • Covid-19 management
Rapid and robust PCR testing for infectious diseases at Innklinikum Altötting and Mühldorf
The Covid-19 pandemic has highlighted the importance of the fast and accurate diagnosis of infectious diseases in clinical settings. Harald Maier discusses the implementation of rapid molecular diagnostics in the central clinical diagnostics laboratory at Innklinikum Altötting and Mühldorf, highlighting how the use of PCR testing has benefitted the hospital during the Covid-19 pandemic.
News • Cell production changes as an early warning
Blood test could predict future risk of leukaemia
A blood test could predict risk of developing leukaemia in the elderly population years in advance by identifying changes in blood cell production, according to new research.
News • Coronavirus research
How the Omicron variant dodges the immune system
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from Geneva reveals the exceptional capacity of Omicron to evade our immunity.
News • Nanometer-scale imaging
Microscopy technique enables 3D super-resolution
Research team led by Göttingen University combine two techniques to achieve isotropic super-resolution imaging.
News • Nanochannels
Groundbreaking: Nanofluidic scattering microscopy
To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.
News • Vortex fluidic device
Next step in rapid diagnostics for infectious diseases
The speedy, high-tech method of inexpensive, accurate and high-throughput protein biomarker assay testing is being touted as a much-needed development in point-of-care (PoC) testing.
Article • Patient-based real-time approach
PBRTQC: improving quality control in the lab
Implementing patient-based real-time quality control (PBRTQC) protocols within the laboratory testing setting can offer benefits in terms of patient safety and reducing risks.
