Article • Cancer diagnostics
Bringing liquid profiling to the clinic
Liquid profiling is offering clear benefits in terms of cancer diagnostics and targeted therapy, but challenges remain in bringing it into the clinic.
News • Cancer proliferation
3D tumour model to unveil metastasis mechanism
Model tumour systems could help explain whether pressure differences can push cancer cells into their surroundings – a basic mechanism behind metastasis.
Article • Chromatogram analysis
AI raises reliability for peak detection in mass spectrometry
Chromatograms from mass spectrometry feature characteristic peaks to signify the response of a target molecule. Artificial intelligence can help in the challenging task of identifying these peaks.
News • From decades to days
Single test for over 50 genetic diseases cuts diagnosis
A DNA test has been shown to identify a range of hard-to-diagnose neurological and neuromuscular genetic diseases quicker and more-accurately than existing tests.
Article • Experience report from Portugal
Going digital: no reason to delay
The future of pathology is digital – for many departments, transformation requires major modifications but promises significant advantages. Professor Catarina Eloy outlines the vital elements.
Article • AI introduction into clinical workflows
The rocky (but worthwhile) road to digital pathology
Close liaison between pathologists and data scientists is pivotal in the successful introduction of digital pathology and artificial intelligence (AI) into clinical workflows, according to one of France’s leading pioneers in the field.
Article • Experience report
Switch to digital pathology bears fruit
Fully digitising pathology operations has led to greater efficiency, cost savings, and quicker diagnosis for the Laboratory of Pathology East Netherlands (LabPON).
News • ATP and lactates in the blood
A sensor to monitor disease severity
Scientists have developed a prototype sensor that could help rapidly measure adenosine triphosphate and lactate levels in blood samples, aiding in the rapid assessment of disease severity.
News • Large study
Blood test for Alzheimer’s highly accurate
When combined with genetic risk factors, the test was up to 93 percent accurate at identifying people at risk of Alzheimer's dementia.
News • Adaptable for screening
An optical methodology for rapid detection of COVID-19
The tool has made it possible to detect SARS-CoV-2 in exudate from symptomatic patients with a sensitivity of 100% and a specificity of 87.5%
News • MS biomarker
Blood marker gives new insights into multiple sclerosis
Nerve damage in multiple sclerosis can be detected via the concentration of neurofilament light chain in the blood. This could offer valuable information on future disease course and therapy effectiveness.
Sponsored • Liquid handling
Revolutionising Molecular Diagnostics With PurePrep TTR
With micro-organisms and viruses constantly developing, mutating, and evolving, diagnostics must adapt just as rapidly. Advanced laboratory technology and instruments are undeniably a prerequisite for best practice in life sciences and biotechnology.
Chemistry & immunochemistry
Fujifilm Wako – Hyaluronic Acid LT Assay
Hyaluronic Acid LT Assay is an in vitro diagnostic test (IVD) for the quantitative determination of hyaluronic acid based on the latex agglutination method. This turbidimetric method can be applied to general clinical chemistry analyzers.
News • Cancer therapy
Chemo after breast cancer surgery? Gene expression test to help decision
Physicists from Leipzig University have developed gene expression tests to examine whether additional chemotherapy is necessary and really effective after breast cancer surgery.
News • Machine learning
Using Raman spectroscopy and AI for SARS-CoV-2 detection
Researchers have developed a noninvasive and reagent-free technique for the efficient detection of COVID-19.
News • Women's health
Breast and ovarian cancer risk assessment from cervical samples
Scientists have discovered a means of identifying the risk of breast and ovarian cancer by measuring epigenetic changes in cervical samples from over a thousand women.
Article • Regulatory issues for AI and digital pathology
IVDR: a complex issue and a 'missed opportunity'
Despite a five-year transition period for In-vitro Diagnostic Medical Device Regulation (IVDR), experts fear many actors in the field are still not prepared for the regulations coming into force.
News • New insights into antibody response
How the immune system reacts to coronavirus variants
Researchers from Charité – Universitätsmedizin Berlin and Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) present new findings on the immune response against SARS-CoV-2.
News • Cardiology insights
Lab-grown heart cells 'mimic' disease in vitro
Heart cells from a patient with an inherited heart disease called arrhythmogenic cardiomyopathy do not contract correctly when grown in the laboratory, researchers from Osaka University have found.
News • Sensitivity and response detection
How long do tests detect SARS-CoV-2 antibodies? New insights
How long can Covid-19 antigen tests reliably tell the antibody status? Researchers at the Paul-Ehrlich-Institut identified several factors that affect the detection duration.
News • Autohaem smear and smear+
Automating blood smears for malaria diagnosis
Researchers have developed a device that removes one of the biggest bottlenecks preventing quick, reliable malaria diagnosis.
Chemistry & immunochemistry
Fujifilm Wako – NEFA-HR(2) Assay
Non-Esterified Fatty Acids (NEFA) are one of the most important metabolites and energy source of peripheral tissues. The amount of NEFA in serum decreases by physical exercise and increases by starvation, cold or smoking. An increase or decrease is also observed in diabetes, hepatic, or endocrine diseases.
Chemistry & immunochemistry
Fujifilm Wako – Autokit CH50 Assay
Autokit CH50 Assay is an in vitro diagnostic (IVD) test for the quantitative determination of total complement activity in human serum. The complement system is a part of the immune system that enhances/complements the ability of antibodies and phagocytic cells to clear pathogens from an organism.
News • Glioblastoma
Blood test for brain tumors possible
Researchers at the University of Sussex are one step further to developing a blood test capable of diagnosing the most aggressive form of brain tumour.
News • Multiple tumor tissue biomarkers
MOSAICA: next-generation biopsy technology
A new biopsy tool will enable scientists and clinicians to simultaneously profile many biomarkers in cells and tissues.