Doctors have reported that partial or total loss of the sense of smell is often an early symptom of infection with SARS-CoV-2, the virus that causes COVID-19. Now, researchers reporting in ACS Chemical Neuroscience have shown that in mice, two proteins required for SARS-CoV-2 entry are produced by cells of the nasal cavity that contribute to odor detection.
Computed tomography (CT) is one of the most effective medical tests for analysing the effects of many illnesses, including COVID-19, on the lungs. An international team led by the Universitat Oberta de Catalunya (UOC) has developed a new method that improves the quality of the images obtained from CT scans. The algorithm, which has been tested on simulated data, enables them to distinguish…
Why does every person react differently to an infection with the coronavirus SARS-CoV-2? Why do some people have no symptoms or only mild symptoms of COVID-19, the disease which it causes? And why do some people become so severely ill that they require ventilators or even die? These questions are being investigated by Professor Mascha Binder, director of the Department of Internal Medicine IV at…
In an international collaboration led by Lund University in Sweden, researchers have used synchrotron light to study what happens to the nerves in diabetes. The technique shows the 3D-structure of nerve fibers in very high resolution. “This knowledge can be used to map mechanisms for how nerve fibers atrophy and grow back. It means that we can better understand how diabetes affects the nerves…
One of the main features of colorectal cancer is that there are considerable differences between the tumors of individual patients - at genetic level and hence in terms of the response to treatment too. Researchers from the German Cancer Consortium (DKTK) have developed a method that allows these differences to be identified more effectively.
Researchers at Northwestern University are using artificial intelligence (AI) to speed up the search for COVID-19 treatments and vaccines. The AI-powered tool makes it possible to prioritize resources for the most promising studies — and ignore research that is unlikely to yield benefits. In the midst of the pandemic, scientific research is being conducted at an unprecedented rate. The Food and…
Artificial intelligence (AI) may be an aid to interpreting ECG results, helping healthcare staff to diagnose diseases that affect the heart. Researchers at Uppsala University and heart specialists in Brazil have developed an AI that automatically diagnoses atrial fibrillation and five other common ECG abnormalities just as well as a cardiologist. The study has been published in Nature…
Researchers in virology and veterinary bacteriology at the University of Bern have cloned the novel coronavirus (SARS-CoV-2). The synthetic clones are being used by research groups worldwide to test corona samples, find antiviral drugs and develop vaccines as quickly as possible. The method developed in Bern can also be used in future to combat other highly infectious viruses. In the…
Using machine learning, a team of Western computer scientists and biologists have identified an underlying genomic signature for 29 different COVID-19 DNA sequences. This new data discovery tool will allow researchers to quickly and easily classify a deadly virus like COVID-19 in just minutes – a process and pace of high importance for strategic planning and mobilizing medical needs during a…
Our immune system not only protects us against infection, but also against cancer. This powerful protection is based in particular on the activation of special cells of the immune system, CD8+ T cells. These cells recognize infected or cancer cells and kill them specifically. “The ability of the immune system and especially CD8+ T cells to eliminate cancer cells in tissues such as the lung, gut…
Niels-Bjarne Woods, a researcher at Lund University in Sweden, has developed lung-specific mesenchymal stem cells to treat inflammation of the lungs and fibrosis. This research now may be the needed breakthrough for treatment of the severe respiratory issues related to COVID-19. A clinical study may soon be underway contingent on a successful application to the Swedish Medical Products Agency.…
The COVID-19 pandemic could, over the next year, lead to a 20% rise in the number of deaths from people who have been newly diagnosed with cancer, according to research supported by DATA-CAN. The analysis is the first to focus on the impact of the emergency on mortality rates in people with cancer and uses data from the health records of over 3.5 million patients in England.
Researchers at Aalto University and Turku PET Centre have developed a new method for simultaneous imaging brain activity from two people, allowing them to study social interaction. In a recent study, the researchers scanned brain activity from 10 couples. Each couple spent 45 minutes inside the MRI scanner in physical contact with each other. The objective of the study was to examine how social…
Diabetes is called an incurable disease because once it develops, it does not disappear regardless of treatment in modern medicine. Having diabetes means a life-long obligation of insulin shots and monitoring of blood glucose levels. Recently, a research team at Pohang University of Science and Technology developed a wirelessly driven ‘smart contact lens’ technology that can detect diabetes…
Researchers at Karolinska Institutet and the University of North Carolina have mapped out the cell types behind various brain disorders. The findings are published in Nature Genetics and offer a roadmap for the development of new therapies to target neurological and psychiatric disorders.
Researchers in The University of Texas at El Paso’s (UTEP) Department of Chemistry and Biochemistry have developed a nanohybrid vehicle that can be used to optimally deliver drugs into the human body. The research was published in ACS Applied Materials & Interfaces. Leading the study are Mahesh Narayan, Ph.D., professor, and Sreeprasad Sreenivasan, Ph.D., assistant professor, both from the…
Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells. The identification of these cells by researchers from the Wellcome Sanger Institute, University Medical Centre Groningen,…
A team of researchers from Empa, ETH Zurich and Zurich University Hospital has succeeded in developing a novel sensor for detecting the new coronavirus. In future it could be used to measure the concentration of the virus in the environment - for example in places where there are many people or in hospital ventilation systems. Jing Wang and his team at Empa and ETH Zurich usually work on…
Scientists at the University of Cambridge have found an association between living in an area of England with high levels of air pollution and the severity of COVID-19, the disease caused by the SARS-CoV-2 virus. Because of the urgent need to share information relating to the pandemic, the researchers have published their report on MedRXiv. It has not yet been peer-reviewed. However, the…
Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer’s disease. Researchers used the “molecular scissors” of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease. The exact causes of Alzheimer’s disease remain unknown, but one of the most well- supported theories focuses on a protein called amyloid beta.…
HM Hospitales, a leading Hospital Group in Madrid, decided to provide the international scientific community with totally anonymized health data regarding patients being treated for the SARS-CoV-2 virus in their facilities.
European photonics scientists are developing an ultrasensitive laser sensor that detects coronavirus at the earliest point of infection from a saliva or nasal swab in minutes.
Researchers from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin have released a crucial report in response to the COVID-19 pandemic.
Researchers from Cambridge, UK, and Germany have reconstructed the early “evolutionary paths” of COVID-19 in humans – as infection spread from Wuhan out to Europe and North America – using genetic network techniques.
The number of cases tested positive for COVID-19 initially grew exponentially in China, but then slowed down. Dirk Brockmann, professor at Humboldt-Universität zu Berlin (HU) and project group leader at the Robert Koch-Institut (RKI), and his postdoc Benjamin F. Maier have developed a diffusion model that takes into account the effect of social distancing and other measures to explain this…
