3-D analysis
RNA molecules in high resolution
University of Maryland scientists have developed a method to determine the structures of large RNA molecules at high resolution.
#research
Interrelationship
Impact of COVID-19 on cancer treatment
The COVID-19 pandemic has impacted virtually every aspect of cancer care and research– from introducing new risks for cancer patients to disrupting the delivery of cancer treatment and the continuity of cancer research.
Using artificial lungs
How COVID-19 causes blood clots
Scientists at EPFL are using technology to better understand how coronavirus causes blood clots in some patients. They have developed a simplified model of a lung that lets them observe, for the first time, how the virus attacks the cells lining blood vessels.
High‐throughput magnetic actuation
Understanding breast cancer metastasis through novel testing platform
A team at Purdue University has developed a novel testing platform to evaluate how breast cancer cells respond to the recurrent stretching that occurs in the lungs during breathing. The technology is designed to better understand the effects that the local tissue has on metastatic breast cancer to study how metastases grow in a new tissue.
For breakthroughs against Hepatitis C
Nobel Prize in Medicine goes to Harvey J. Alter, Michael Houghton and Charles M. Rice
The 2020 Nobel Prize in Medicine is awarded to three scientists who have made a decisive contribution to the fight against blood-borne hepatitis, a major global health problem that causes cirrhosis and liver cancer in people around the world. Harvey J. Alter, Michael Houghton and Charles M. Rice made seminal discoveries that led to the identification of a novel virus, Hepatitis C virus. Prior to…
Focused ultrasound
Delivering drugs to the brain with pinpoint accuracy
Focused ultrasound waves help researchers at ETH Zurich to deliver drugs to the brain only to where their effect is desired. This method is set to enable treatment of psychiatric and neurological disorders and tumours with fewer side effects in the future.
Trajectory browser
New tool shows main highways of disease development
As people get older they often jump from disease to disease and carry the burden of more chronic diseases at once. But is there a system in the way diseases follow each other? Danish researchers have for the past six years developed a comprehensive tool, the Danish Disease Trajectory Browser, that utilizes 25 years of public health data from Danish patients to explore what they call the main…
Fending off the coronavirus
The role of T-cells in SARS-CoV-2 virus defense
Our immune system can efficiently fend off viral diseases. Two types of immune cells play an important role in this process: The T-cells, which firstly can directly destroy virus-infected cells and secondly enable the formation of efficient, virus-neutralizing antibodies by B-cells. These two cell types also play a crucial role in the immune defense against SARS-CoV-2 infection. Whereas antibody…
Distant metastasis-free interval explored
High-risk breast cancers: Mode of detection is linked to patient prognosis
Breast cancers that are detected in the interval between national screening programme mammograms have a worse prognosis than those detected at the time of a screening, even if they have the same biology, according to research presented at the 12th European Breast Cancer Conference. Analysis of results from over eight years’ follow-up of the international MINDACT randomised phase III clinical…
'Rush to publish'
Have research standards suffered during COVID-19?
The COVID-19 pandemic has created a flood of potentially substandard research amid the rush to publish, with a string of papers retracted or under a cloud and a surge in submissions to pre-print servers where fewer quality checks are made, a leading ethicist has warned in the Journal of Medical Ethics. This has implications for patients, clinicians, and potentially government policy, says…
Genetic
App analyses Covid-19 genome on a smartphone
A new mobile app has made it possible to analyse the genome of the SARS-CoV-2 virus on a smartphone in less than half an hour.
Improving mobility after hip or knee replacement surgery
Wearable device research: "GaitSmart" to help orthopaedic patients
Patients who have hip or knee replacements are set to get more support with their recovery following the launch of a new research study that uses wearable technology to monitor walking patterns. The Norfolk and Norwich University Hospital (NNUH) has joined forces with Dynamic Metrics Ltd (DML) to develop and test a system to study mobility and improve a patient’s gait after a joint replacement.
Comfy, but risky
Why many ventilation systems may increase risk of COVID-19 exposure
Ventilation systems in many modern office buildings, which are designed to keep temperatures comfortable and increase energy efficiency, may increase the risk of exposure to the coronavirus, particularly during the coming winter, according to new research.
Cell coordination explored
Why wound-healing comes in waves
How do cells in our bodies ask for directions? Without any maps to guide them, they still know where to go to heal wounds and renew our bodies. Edouard Hannezo and his group at the Institute of Science and Technology Austria (IST Austria) together with Tsuyoshi Hirashima and his group at Kyoto University just published a new study in Nature Physics that shows how mechanical and chemical waves…
Lipids, lysosomes, and autophagy
Researchers find the keys to preventing kidney injury
Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of. Dealing with this cellular “trash” are spherical, membrane-bound organelles called lysosomes filled with a mixture of potent enzymes. In a process called autophagy,…
Insufficient protective properties
COVID-19: Experts warn of KN95 masks quality issues
An analysis by ECRI, the U.S.’s largest patient safety organization, shows that up to 70 percent of KN95 masks it tested do not meet its standards for effectiveness, raising risks of contracting COVID-19 for care providers and patients at hospitals and other healthcare organizations that imported masks from China. Researchers at ECRI, a not-for-profit organization that for decades has advised…
Reduced complications, death
COVID-19: The benefits of vitamin D
Adequate levels of vitamin D reduces complications and deaths among COVID-19 patients, reveals new research performed at the Boston University School of Medicine. Hospitalized COVID-19 patients who were vitamin D sufficient, with a blood level of 25-hydroxyvitamin D of at least 30 ng/mL (a measure of vitamin D status), had a significant decreased risk for adverse clinical outcomes including…
Artificial neurons
Nanodevices identify mutations in viruses
Scientists from Texas A&M University, Hewlett Packard Labs and Stanford University have developed a new nanodevice that acts almost identically to a brain cell.
Tumor growth
New insights into colorectal cancer
Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer.
Basis for a passive vaccination
Researchers identify highly effective antibodies against SARS-CoV-2
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development of a passive vaccination. In this process, they have also discovered that some SARS-CoV-2 antibodies bind to tissue samples from various organs, which could potentially…
Nitrogen dioxide levels
Air pollution linked to higher COVID-19 mortality
Scientists have unearthed a possible link between the severity of COVID-19 and air quality. The preliminary study – looking at whether areas with higher levels of air pollutants in England are associated with a larger number of cases/deaths from COVID-19 – was conducted by a team from the University of Cambridge. Aware of the effects that air pollutants have on human health – and that…
COVID-19 disinfection
New insights into SARS-CoV-2 surface stability and temperature susceptibility
Surface disinfection has proved an effective method to control COVID-19 infection, as virologists from the Ruhr University Bochum (RUB) have shown. However, an effective disinfection strategy against Coronavirus must consider various factors, says Professor Eike Steinmann. The head of the Department of Molecular and Medical Virology at the RUB explained when disinfection is an effective procedure…
Gels for drug delivery systems
'Soft' 3D printing could jump-start creation of tiny medical devices
Researchers at the U.S. National Institute of Standards and Technology (NIST) have developed a new method of 3D-printing gels and other soft materials. Published in a new paper, it has the potential to create complex structures with nanometer-scale precision. Because many gels are compatible with living cells, the new method could jump-start the production of soft tiny medical devices such as…
Lung disease burden
New research doubles estimate for COPD prevalence
Around 550 million people have chronic obstructive pulmonary disease (COPD), according to two University of Manchester medical students. The figure more than doubles the previous estimate of 251 million people with the illness linked to smoking by the World Health Organization (WHO) Global Burden of Disease Study. The University of Manchester students, Emily Hammond and Charles McDonald, made the…
Silent alarm
‘Silent’ COVID-19 patients may still act as a spreader, warn experts
People with ‘silent’ COVID-19 infection have as much coronavirus in their noses and throats as those with symptoms, reveals research published online in the journal Thorax. Given how many of these people there are---a fifth of those infected, the study findings show--they may have a key role in driving the spread of COVID-19, warn the researchers, who go on to suggest that this warrants…