Tissue

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Protein test instead of cystoscopy

A recent study from the Heidelberg-based company Sciomics, a spin-off from scientists from the German Cancer Research Center (DKFZ), has presented an advanced method to predict the recurrence of bladder cancer after surgery. The method, which can help avoid frequent cystoscopy examinations in a majority of patients, is based on an analysis of the protein composition of cancer tissue obtained…

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Trail blazing bariatric surgery devices

Major advances in Natural Orifice Transluminal Endoscopic Surgery (NOTES) lead to a tremendous interest in new surgical endoscopes. The advantages of minimally invasive surgery via natural body orifices, such as the mouth, are obvious: less post-operative pain, a minor infection rate, minor incisional hernia, shorter hospitalisation and, finally, better cosmetic results. Karoline Laarmann reports

High hopes for elastography

Dr Bill Svensson believes that elastography has the potential to improve diagnosis of breast cancer, reduce the number of false positives in the detection of the condition and also lead to fewer biopsies performed as accuracy of imaging improves further. This June he highlighted the potential of elastography and the developments in the imaging modality at two sessions at the United Kingdom…

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Reading tissues

The trend towards personalised medicine implies the development of targeted cancer therapy. Tissue based examinations by pathologists play a key role in this trend. However, the relevance is still underestimated as pathologist Professor Manfred Dietel noted in his lecture at the European Forum on Oncology 2010 in Berlin, which explained what pathology already actually renders to targeted cancer…

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The future of mass spectrometry in laboratory medicine

The world consists of molecules – so do we. With the progression of measurement tools such as microscopes, centrifuges, or spectrometers, mankind is becoming better and better in identifying the substances from which our world is made. Today, with the technical developments in mass spectrometry, biomolecules can be weighted with the highest precision and accuracy ever known, placing it among…

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New EU project CORONET

Interfaces between the brain and electrical circuits in technical devices or computers open new perspectives for basic research and medical application, e.g., for therapeutic brain stimulation and neuroprosthetics. The new EU project CORONET will develop the technological and theoretical foundations for such future “bio-hybrid” interfaces between biological and artificial nervous tissues.

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Synapses recycle proteins for the release of neurotransmitters

Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, German neuroscientists have now discovered that neurons systematically recycle the protein components necessary for transmitter…

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