Tissue

The notable risks in the use of bone cement

Used in numerous orthopaedic medical procedures, PMMA is a self-curing two component system that includes liquid and powder components. The liquid is methylmethacrylate monomer, a known deadly toxin, and PMMA toxicity is well documented in medical journals and regulatory publications. After many years of reported patient issues related to PMMA, doctors began calling these surgical complications…

Photo

Protein highways keep tissues organized

Precise regulation of tissue architecture is critical for organ function. Single cells build up a tissue by communicating with their environment and with other cells, thereby receiving instructions on whether to divide, change shape or migrate. An interdisciplinary group of researchers from several Max Planck Institutes have now identified a mechanism by which skin cells organize their interior…

Photo

A bright future for biobanks

Ten years ago, molecular biologist Dr Peter H J Riegman set up a unique bio-bank for medical research at the pathology department of Erasmus Medical Centre, Rotterdam, The Netherlands. The Erasmus MC Tissue Bank now holds 30,000 samples from about 15,000 patients. However, when Dr Riegman discusses his bio-bank with international colleagues they do not immediately associate it with a clinic or…

Photo

The European Network for Cell Imaging and Tracking Expertise (ENCITE)

Since June 2009, the focus of research in the European Network for Cell Imaging and Tracking Expertise (ENCITE) has been on finding biomarkers to aid cell transplantation. Funded with €11 million from the European Commission (EC), this major project that runs until 2013, involves 10 countries. Their work is coordinated by the European Institute for Biomedical Imaging Research (EIBIR) network,…

Photo

MR-Elastography

Physicians, over many centuries, have depended on the sense of touch as their hands on method to detect diseases in many body areas. This technique is called palpation. However, though it was known that abnormalities in the stiffness or mechanical environment in tissue may have a profound impact on how many diseases progress, conventional imaging modalities could not display tissue stiffness in…

Photo

Liver stiffness measurements identify patients with rapid or slow fibrosis

A recent study determined that repeated liver stiffness measurements (LSM) in the first year following liver transplant (LT) could discriminate between slow and rapid "fibrosers". LSM were extremely accurate, particularly at the 6-month post LT point, in detecting severity of fibrosis. Determining those at risk for a recurrence of hepatitis C virus (HCV) allows for early-stage administration of…

Photo

A Scaffold to regenerate lost bones and tissue

Mother Nature has provided the lizard with a unique ability to regrow body tissue that is damaged or torn - if its tail is pulled off, it grows right back. She has not been quite so generous with human beings. But we might be able to come close, thanks to new research from Tel Aviv University.

Molekulare Bildgebung von Karzinomen

Chirurgen an der Charité haben in kolorektalem Tumorgewebe eine spezifische Anhäufung von Protoporphyrin-IX (PpIX), einem rot-fluoreszierenden Vorläufermolekül des Häms beobachtet. Wir konnten zeigen, dass diese Anhäufung von PpIX darauf zurückzuführen ist, dass das Enzym, das PpIX normalerweise in Häm überführt, die sogenannte…

Photo

A More Direct Delivery of Cancer Drugs to Tumors

An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area.

Photo

Analytica 2008

With 121 high level lectures and 65 published posters, Analytica 2008 - organised by the German Chemical Society (GDCh), the Society for Biochemistry and Molecular Biology (GBM) and the German United Society of Clinical Chemistry and Laboratory Medicine (DGKL) - was again a notable bio-chemistry event.

15 show more articles
Subscribe to Newsletter