News • Tissue scarring
How a Covid-19 infection can damage the kidneys
The Coronavirus SARS-CoV-2 infects the kidneys and contributes to tissue scarring, as shown by researchers from Germany and the Netherlands.
Kidney
Article • WSI, AI and more
New digital frontiers for nephrology
Digital technology solutions create new opportunities in diagnosis and assessment of renal conditions. With whole slide imaging (WSI), improved workflow and better visualization, such technology already yields a ROI for hospitals and laboratories.
News • The 'PodoSighter'
AI identifies key indicator of early kidney disease
Researchers have leveraged the power of digital pathology and computational modeling to detect and quantify podocytes, a specialized type of cell in the kidney that undergoes damaging changes during early-stage kidney disease.
News • Successful investigational procedure
First ever pig-to-human kidney transplantation shows promise for organ replacement
The first investigational transplantation of a genetically engineered, nonhuman kidney to a human body was recently completed at NYU Langone Health—marking a major step forward in potentially utilizing an alternative supply of organs for people facing life-threatening disease.
News • Nephrolith research
Fatty liver disease promotes formation of kidney stones
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in western countries, with an increasing incidence worldwide. Consequences of NAFLD can also include kidney disease and kidney stones, although the mechanisms for the development of these kidney complications as a result of NAFLD have not yet been fully explained. Researchers at the Leibniz Research Centre for Working…
News • Nanoparticle-based contrast agent SAIO
New MRI contrast agent to improve upon gadolinium-based products
Magnetic resonance imaging (MRI) is widely used to identify the narrowing or blockage of blood vessels. Contrast agents improve the visibility of the structures and offer more accurate information of vascular conditions such as vascular blockage and stenosis. Commonly used gadolinium-based contrast agents must be administered in chelated forms due to the gadolinium ions' high toxicity and pose…
News • Immersion is key
Hemodialysis: Virtual reality lessens side effects
Hemodialysis patients routinely experience side effects such as fatigue, lightheadedness and nausea during their treatment sessions. But patients in a study who used a virtual reality program to engage in a mindfulness/meditation exercise reported that these treatment-related symptoms were greatly reduced. Patients in the study wore a head-mounted virtual reality display to participate in a…
News • Immunotherapy side effect
Hope for kidney cancer patients
An autoimmune side effect of immune checkpoint inhibitor (ICI) drugs could signal improved control of kidney cancer, according to a new study by researchers in UT Southwestern's Kidney Cancer Program (KCP).
News • Lipids, lysosomes, and autophagy
Researchers find the keys to preventing kidney injury
Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of. Dealing with this cellular “trash” are spherical, membrane-bound organelles called lysosomes filled with a mixture of potent enzymes. In a process called autophagy,…
News • Hemolysis monitoring
Measuring blood damage in real-time
Scientists at the University of Delaware and Princeton University have developed a method to monitor blood damage in real-time. “Our goal was to find a method that could detect red blood cell damage without the need for lab sample testing,” said Tyler Van Buren, an assistant professor of mechanical engineering with expertise in fluid dynamics. The researchers recently reported their technique…
News • Nephritis as a marker
Kidney an early warning sign for severe COVID-19 cases
A course of action to early detect and treat severe courses of COVID-19 infections has been developed by an expert-team of the University Medical Center Goettingen (UMG). A simple urine test is intended to help medical professionals to recognize warning signs of future decompensation of COVID-19 infections earlier. With the help of a few parameters, the treatment of imminent complications can…
Sponsored • Customer story
Ultrasound improves renal care at St Helier Hospital
St Helier Hospital in the London Borough of Sutton – part of the Epsom and St Helier University Hospitals NHS Trust – has one of the largest renal medicine departments in the UK, and relies on Fujifilm SonoSite point-of-care ultrasound (POCUS) systems to improve care and patient safety. Dr Pritpal Virdee, a senior registrar in the department, explained: “We have a very busy renal department…
News • Donor organ assessment
New quality feature to predict kidney transplant failure
New research indicates that subtle structural features of donated kidneys from living donors may predict the risk of kidney transplant failure in recipients. The findings, which appear in an upcoming issue of JASN, may help clinicians as they evaluate the quality of organs at the time of transplantation. The quality of donated kidneys obtained from living donors is often inferred from their age,…
News • Deep learning & CNN
Algorithm differentiates small renal masses on multiphase CT
A deep learning method with a convolutional neural network (CNN) can support the evaluation of small solid renal masses in dynamic CT images with acceptable diagnostic performance, according to an article published ahead-of-print in the March issue of the American Journal of Roentgenology (AJR). Between 2012 and 2016, researchers at Japan’s Okayama University studied 1807 image sets from 168…
News • "Umbrella" trial
Urine test detects acute kidney transplant rejection
Early non-invasive detection of kidney rejection after transplantation was the central aim of a collaboration between Prof. Dr. Bernhard Banas, Chairman of Nephrology at the University Hospital Regensburg (UKR) and the medical diagnostics company, numares. The results of their joint clinical trial “UMBRELLA” were just published in EBioMedicine and presented at the American Society of…
Sponsored • POCUS
Point-of-care ultrasound – a valuable tool for nephrology
Point-of-care ultrasound (POCUS) systems are becoming a common sight in nephrology departments and renal dialysis clinics, helping clinical staff to evaluate and effectively access the vasculature of dialysis patients. Dr Jean-Yves Bosc, a nephrologist and vascular doctor working at the non-profit private health establishment AIDER SANTÉ in the South of France, has been a champion of ultrasound…
News • Spotting scar muscles of the heart
New MRI technique saves kidneys from gadolinium damage
Traditional MRI (magnetic resonance imaging) scans use the metal gadolinium, which resonates areas of the heart muscles that are not functioning efficiently. However, gadolinium affects the Kidney function. A new 3D MRI computing technique developed by scientists at the University of Warwick calculates strain in heart muscles showing which muscles are not functioning enough without damaging other…
News • End stage kidney disease
Pre-eclampsia increases ESKD risk
Women with pre-eclampsia during pregnancy have a five-fold increased risk of end stage kidney disease (ESKD) later in life compared to women who don’t develop pre-eclampsia during pregnancy, according to a new study. Professor Louise Kenny from the University of Liverpool is one of the co-authors of the study, which is published in PLOS Medicine and also involved researchers at University…
Video • Nuclear magnetic resonance relaxometry
Hydration sensor could improve dialysis
For patients with kidney failure who need dialysis, removing fluid at the correct rate and stopping at the right time is critical. This typically requires guessing how much water to remove and carefully monitoring the patient for sudden drops in blood pressure. Currently there is no reliable, easy way to measure hydration levels in these patients, who number around half a million in the United…
Sponsored • Progressing with a strong partner
Xenios and Fresenius Medical Care take the next step to multi-organ support
In October 2016, Xenios became a part of Fresenius Medical Care (FME), the world’s leading provider of products and services for people with chronic kidney failure. The integration of the expertise from FME and Xenios and thus the combination of the companies’ competences strongly enhances treatment options in critical care within the intensive care unit (ICU) of hospitals across the world.…
News • Seasonal influenza
Why the flu is especially dangerous for kidney failure patients
In patients with kidney failure, influenza-like illness (ILI) likely contributes to more than 1,000 deaths per year. The finding, which comes from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN), points to the importance of protection against, surveillance of, and, where possible, treatment of such infections in patients with kidney dysfunction.…
News • Kidney cancer
Brain metastases: Multidisciplinary care improves outcomes
New data reveals the life expectancy of patients with kidney cancer that’s traveled to the brain has now stretched from months to years. UT Southwestern Kidney Cancer Program investigators report survival rates beyond 2.5 years for some patients with specialized multidisciplinary care. Historically, patients whose kidney cancer had spread to the brain were believed to have only about six months…
Article • CEUS & the kidneys
Contrast-enhanced ultrasound for renal masses
Contrast enhanced ultrasound (CEUS) has proved in trials to be more accurate than computed tomography and MRI and can help eliminate the need for unnecessary biopsies and surgery. Dr Richard Barr, Professor of Radiology at Northeast Ohio Medical University, explains the benefits of the modality.
News • Organ donation
Suitable transplant kidneys may be lost due to flawed testing
New research indicates that many kidneys obtained for transplantation from deceased donors are not being used because of biopsy findings despite their unreliability and reproducibility. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN) and will be published at ASN Kidney Week 2018, may suggest an urgent need to re-examine the…
News • Chronic obstructive pulmonary disease
COPD: Biomarker for kidney disease has unexpected benefits
A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Albuminuria, Lung Function Decline, and Risk of Incident COPD: the NHLBI Pooled Cohorts Study,” Elizabeth C.…