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Obesity, fatty liver, insulin resistance: Liver enzyme might be to blame
German researches have linked the increased production of a certain enzyme in the liver to fatty liver and insulin resistance.
German researches have linked the increased production of a certain enzyme in the liver to fatty liver and insulin resistance.
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent liver diseases worldwide and an estimated 20 million people in Germany are affected.
For almost three quarters of hepatocellular carcinoma (HCC) patients in Europe it is too late for curative treatment because the disease is often only diagnosed at a very advanced stage. Interviewed Professor Guido Gerken MD, Director of the Department for Gastroenterology and Hepatology at University Hospital Essen, about improved and timelier diagnostic capabilities that have already been…
New 3-D simulation models that include haemodynamics enable better treatment of hepatic tumours via radio-embolisation, according to eminent Spanish radiologist José Ignacio Bilbao Jaureguizar.
New MRI techniques are set to offer advances in the earlier detection of liver disease in patients. Radiologists are harnessing the potential of highly-targeted MRI, whilst exploring the imaging modality as a means of delivering non-invasive biomarkers, reducing the need for biopsy to measure treatment response.
NEW: Evolution 3.0 EPIQ ultrasound upgrade offers high-res PureWave crystal transducer technology, shear wave elastography, contrast enhanced ultrasound, and image fusion. Could you ask for more?
Riad Salem, MD, MBA, will be honored with the Society of Interventional Radiology (SIR) Foundation Leaders in Innovation Award March 7, during the group's annual scientific meeting in Washington, D.C., for his work in radioembolization.
Researchers at University of Vienna discover unexpected role of signalling protein in hepatocellular carcinoma.
Scientists have shown that a mutation in a gene called Arid1b can cause liver cancer. The gene normally protects against cancer by limiting cell growth, but when mutated it allows cells to grow uncontrollably. The researchers have shown that two existing drugs can halt this growth in human cells. This points to a new approach to treating liver cancer.
Contrast enhanced ultrasound is part of clinical routine and makes a substantial contribution towards increasing the significance of tissue and organ diagnosis with ultrasound for difficult cases.
Hepatitis B virus (HBV) causes hepatitis B, an infectious disease that afflicts 230 million people worldwide, thereof 440 000 in Germany. Persistence of the virus in liver cells leads to progressive organ damage in the patient and contributes to a high risk of cirrhosis and liver cancer development. Providing a new paradigm to hepatitis B understanding, researchers at the German Cancer Research…
‘Already used in adults for several years, elastography is a promising tool in paediatric imaging,’ according to radiologist Dr Mehrak Anooshiravani-Dumont, from Geneva University Hospital. ‘It allows detection of changes in the mechanical properties of tissues, such as fibrosis, based on viscoelastic characteristics.‘
Researchers have found the “bad seeds” of liver cancer and believe they could one day reprogram them to remain responsive to cancer treatment, a new study has found.
A new cellular structure responsible for previously unexplained rejection of organ transplants has been identified by researchers at the University of Montreal Hospital Research Centre (CRCHUM.)
The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the U.S. Centers for Disease Control and Prevention.
Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease.
People waiting for organ transplants may soon have higher hopes of getting the help that they need in time. Researchers at the RIKEN Center for Developmental Biology have developed a new technique that extends the time that donor organs last and can also resuscitate organs obtained after cardiac arrest.
A multi-year study led by researchers from the Simons Center for Data Analysis (SCDA) and major universities and medical schools has broken substantial new ground, establishing how genes work together within 144 different human tissues and cell types in carrying out those tissues' functions.
As part of an effort to understand how an experimental drug for atherosclerosis causes the build-up of fat in the liver, scientists have developed a computer model that can predict how the rate at which liver stores fat in response to various situations.
Surgeons at the University Hospitals Leuven have used a new technique for two recent liver transplants: in both cases the organ was preserved prior transplantation in a device that mimics the environment of that in the human body, making sure the liver stays ‘healthier’. The device can even assess and improve the quality of the liver.
40 percent of people in the EU suffer from non-alcoholic steatohepatitis, a disease which is becoming increasingly more frequent as a result of diabetes and excess weight in an affluent society.
Ask about UltraFast ultrasound and you might expect a technical answer explaining why the ultrasound is faster. However, for Stéphanie Franchi-Abella MD, fast means just fast, an ultra-quick acquisition she can take of a squirming, agitated new-born in the blink of an eye. ‘These babies are small and breathing rapidly, the organs are moving fast in the image and it’s sometimes difficult to…
Scientists from the German Cancer Research Center (DKFZ) and the Medical Faculty in Mannheim at Heidelberg University are searching for new approaches to prevent liver fibrosis. They have identified a surface molecule on special liver cells called stellate cells as a potential target for interfering with this process. When the researchers turned off the receptor, this led to reduced liver…
Researchers at the Hubrecht Institute and the University Medical Center (UMC) Utrecht successfully developed a culturing system for human liver stem cells as well as stem cells from pancreatic cancer. They describe the development of these culturing systems in two articles in this week’s edition of Cell magazine.
At least 60% of liver lesions can be characterised purely by ultrasound. Screening and examinations of supposedly healthy patients often result in an accidental discovery of liver lesions. According to Dr Antonius Schuster MD MBA, Head of the Department of Radiology at the LKH Bregenz, (Vorarlberg). ‘The prevalence of such changes is around 20% of patients examined’. Depending on a…