
News • Colon cancer
Biomarkers identify aggressive Tumors
Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy.
Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy.
Billy Boyle, Founder and CEO of Owlstone Medical, a diagnostics company developing a breathalyzer for disease, is to be awarded the Royal Academy of Engineering’s prestigious Silver Medal. The award recognizes engineer Billy’s work in spearheading the development of the company’s Breath Biopsy platform and driving a vision to save 100,000 lives and $1.5 billion in healthcare costs.
Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics.
Pentax Medical EMEA announces its continued cooperation with SMART Medical to support the distribution and deployment of SMART’s G-EYE technology integrated with Pentax Medical’s HD+ systems to the EMEA market.
Colon cancer is one of the most common forms of cancer in Germany. Prof. Dr. med. Sebastian Zeißig, group leader at the DFG Research Center for Regenerative Therapies Dresden (CRTD) - Cluster of Excellence at the TU Dresden and physician at the Department of Medicine I, University Hospital Carl Gustav Carus Dresden, has now shown a decisive role of gut bacteria in the regulation of intestinal…
A leading cause of cancer deaths worldwide, colon cancer is famously resistant to treatment. There are many reasons for this, but one has to do with a group of persisting cancer cells in the colon that cause relapses. Conventional therapies against them are mostly ineffective. EPFL scientists have now identified a biological mechanism that can be exploited to counteract colon cancer relapses.
Led by Professor Teoh Swee Hin, scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells. Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.
Chemists at Caltech have developed a new sensitive technique capable of detecting colorectal cancer in tissue samples—a method that could one day be used in clinical settings for the early diagnosis of colorectal cancer.
‘Health insurers should keep a tighter rein on the quality of endoscopic interventions because, mostly, they represent a gentler alternative to surgery,’ asserts international expert Horst Neuhaus, during an EH interview. Report: Daniela Zimmermann/Juliane Dannert
Innovative endoscopy system improves adenoma detection. Endoscopes are thin flexible tubes with imaging capabilities that doctors use to view the upper and lower GI tracts of their patients. The Fuse system uses three small cameras at the tip of a flexible GI endoscope, as compared with one at the tip of a standard, forward-viewing endoscope. With a wider 330° view, physicians see nearly twice…
Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression. This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs.
The number of cancer patients in Germany continues to rise steadily. An increase in the number of newly diagnosed cases of 14% is expected by 2020 compared to 2008. Therefore early detection is increasingly the focus of attention.
Founded in Germany 25 years ago, EKF Diagnostics’ PLC HQ is currently in Cardiff, Wales, where the firm is pursuing the development of a molecular assay for specific cancer types.
For gastrointestinal exams, MRI fluoroscopy offers an alternative to conventional methods of swallowing and gastric emptying that are so repugnant to patients.
Johns Hopkins study finds robotic colon surgery just as effective as laparoscopy but more expensive
The NHS has to overcome people’s ‘status-quo bias’ if it is to increase the number of screenings for bowel cancer.
Colon cancer remains the second most common cause of cancer-related death in the Western world with 450,000 citizens in Europe newly diagnosed and 230,000 deaths annually (Source: Globalscan 2008).
Cancer specialists everywhere increasingly face new findings from molecular biology. Genetic profiling of tumours opens up entirely new perspectives on the disease. How to cope with and integrate new insights into cancer diagnosis and treatment was among key issues discussed at the 2nd European Forum on Oncology, held in Berlin this May
Speaking at the ESR meets Radiation Oncologists session, Dr Gina Brown (Royal Marsden NHS Foundation Trust, London) emphasised that radiologists’ input is critical in treatment and surgical decisions and that radiologists, oncologists and surgeons should work more closely in the planning and delivery of treatment and surgery for the overall benefit and long-term well-being of rectal cancer…
Reliable Cancer Therapies (RCT) celebrates the first anniversary of its website in style. The Swiss non-for-profit organization has completed comprehensive guides for cancer patients and their relatives, which are now available on its website.
The trend towards personalised medicine implies the development of targeted cancer therapy. Tissue based examinations by pathologists play a key role in this trend. However, the relevance is still underestimated as pathologist Professor Manfred Dietel noted in his lecture at the European Forum on Oncology 2010 in Berlin, which explained what pathology already actually renders to targeted cancer…
The future of colon cancer screening may be surprisingly simple. ColoMarker™, an innovative blood test to detect the early stages of colon cancer is generating plenty of attention from a wide audience, including from some of the world’s leading researchers in cancer biomarkers and gastrointestinal medicine.
In 2006, about 307,432 new cases of colorectal cancer arose in the European Union. The rates varied by a factor of two for women and three for men. The lowest rates were in Greece; the highest in Hungary and the Czech Republic. The incidence of colorectal cancer is increasing in Europe, particularly in the south and east, where rates were originally lower than in Western Europe.
Colorectal cancer is a suitable target for screening when it has a relatively high incidence – the second highest cancer incidence among women and third among men in Europe – and has a high mortality (~50% are expected to die of the disease), but can be cured if detected at an early stage.
Brain tumors are the primary cause of cancer mortality in children. Even if a cure is possible, young patients often suffer tremendously from the stressful treatment which can be harmful to the developing brain. Therefore, there is an urgent need for target-oriented, gentle treatment methods. The most important childhood brain tumors are medulloblastoma, which is diagnosed in approximately one…