Women show persistent memory impairment after concussion
Women may have a more difficult time than men in recovering from concussion, according to a new study published online in the journal Radiology.
News • Research
Neurons constantly rewrite their DNA
Johns Hopkins scientists have discovered that neurons are risk takers: They use minor ‘DNA surgeries’ to toggle their activity levels all day, every day. Since these activity levels are important in learning, memory and brain disorders, the researchers think their finding will shed light on a range of important questions.
Article • Cancer diagnostics I
Ambiguity calls for a second opinion
Each year, approximately 1.6 million women in the USA have breast biopsies to diagnose or rule out cancer. Pathological diagnosis is considered the gold standard – how accurate are these diagnoses? Report: Cynthia E. Keen
Article • Cancer diagnostics II
New nanoparticle could enhance MRI scanning
Scientists in the UK have designed a new self-assembling nanoparticle that targets tumours and could lead to quicker diagnosis of cancer. Researchers at Imperial College London report that a new self-assembling nanoparticle can adhere to cancer cells, thus making them visible in MRI scans and possibly eliminate the need for invasive tissue biopsies. Report: Mark Nicholls
Article • Preamble
Keeping up with an ever-evolving science
Expecting 10,000 participants, prior to the 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Copenhagen, Denmark (25-28 April) its Programme Director, Professor Winfried V Kern MD, was keen to point out: ‘The findings and recommendations that emerge from this vibrant platform each year have, in the past, had a tremendous impact not only on guidelines and best…
News • DRUG resistance III
Antibiotic Armageddon in Europe by 2025
A group of leading scientists has warned that Britain and Europe collectively could face more than a million deaths in an impending "Antibiotic Armageddon” unless more is spent on developing new cures, rapid diagnostics and preventative measures to combat the spread of drug resistant diseases.
Interview • Connected Care
Improving medication adherence via a patient-centric platform
Dr Stefan Becker, a trained medical doctor with an M.B.A. degree, works as a senior nephrologist and transplant officer at Essen University Hospital and manages its Institute for Drug Safety. In an interview he spoke about his involvement in e-health projects in the field of connected care that he carries out with interdisciplinary teams, including the Fraunhofer Institute for Software and…
Article • Black-blood
Seeking time-efficiency and high contrast
Black Blood Imaging may not sound helpful – but it is. The MRI specialist can work with clearer contrasts and gain greater certainty in tumour diagnosis as well as the detection of inflammatory changes in tissue.
Article • Telehealth study
England’s Florence looks like a winner
Given the increasing focus on telehealth and telecare services aimed at improving long-term patients’ living conditions and save costs, numerous pilots in various countries have been conducted for proof of concept purposes. Among these, the United Kingdom’s ‘Whole System Demonstrator’ (WSD) programme is the largest randomised controlled trial. Set up by the English National Health Service…
Fighting HIV with antibodies
30 years after HIV was discovered to be the cause of the acquired immune deficiency syndrome AIDS, and despite intensive research, no vaccine or cure has yet been found. An international team of scientists, in collaboration with the German Center for Infection Research (DZIF) and the University Hospital of Cologne, has now tested a new generation of antibodies in humans for the first time. They…
Article • Growing Cells
Novel tissue substitute made of high-tech fibers
Regenerative medicine uses cells harvested from the patient’s own body to heal damaged tissue. Fraunhofer researchers have developed a cell-free substrate containing proteins to which autologous cells bind and grow only after implantation.
Article • Computer Model
How our livers will store fat?
As part of an effort to understand how an experimental drug for atherosclerosis causes the build-up of fat in the liver, scientists have developed a computer model that can predict how the rate at which liver stores fat in response to various situations.
News • Research
Influence of magnetic fields on neurodegenerative diseases
Low-frequency alternating magnetic fields such as those generated by overhead power lines are considered a potential health risk because epidemiological studies indicate that they may aggravate, among other things, neurodegenerative disorders such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS). However, a recent study by researchers at the Institute of Pathobiochemistry at the…
Researchers create 'Wikipedia' for neurons
The decades worth of data that has been collected about the billions of neurons in the brain is astounding. To help scientists make sense of this "brain big data," researchers at Carnegie Mellon University have used data mining to create a publicly available website that acts like Wikipedia, indexing physiological information about neurons.
Article • Optical imaging
Faster than light
PET scanners are not the only way to image radiotracers. Recent work developed around a phenomenon called Cerenkov luminescence aims to bring a new modality out of preclinical development and into clinical practice.
Article • Human Locomotion
Researchers improve efficiency of human walking
Unpowered exoskeleton developed by Carnegie Mellon and North Carolina State researchers helps individuals walk using less energy.
News • Plastic plus egg whites
Recipe for antibacterial plastic
Bioplastics made from protein sources such as albumin and whey have shown significant antibacterial properties, findings that could eventually lead to their use in plastics used in medical applications such as wound healing dressings, sutures, catheter tubes and drug delivery, according to a recent study.
How to tame most aggressive breast cancers
Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad.
Long-standing mystery in membrane traffic solved
Researchers discovered that NSF unravels a single SNARE complex using one round ATP turnover by tearing the complex with a single burst, contradicting a previous theory that it unwinds in a processive manner.
MRI may replace biopsies
Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn’t cancer usually requires a biopsy to study cells directly. Now results of a Johns Hopkins study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.
News • Obesity
'Nurture' more important than 'nature' for overweight children
Parents’ lifestyles, rather than their genes, are primarily responsible for their children being overweight according to research by the Centre for Economic Performance, based at the London School of Economics and Political Science (LSE). Researchers compared the weight of biological and adopted children to that of their parents to determine whether children inherit their weight problems or…
News • Neuropsychiatric disorders
Philips develops handheld blood test
Royal Philips today announced that it has entered into a multi-year development agreement with Janssen Pharmaceutica N.V. (Janssen). The collaboration aims to develop a new handheld blood test to provide doctors with a novel tool to improve the care of patients with neuropsychiatric disorders.
News • Organ Transplantation
Innovative technique for liver transplants
Surgeons at the University Hospitals Leuven have used a new technique for two recent liver transplants: in both cases the organ was preserved prior transplantation in a device that mimics the environment of that in the human body, making sure the liver stays ‘healthier’. The device can even assess and improve the quality of the liver.
Article • Power in Hybrid
PET/MRI – powerful diagnostic tool improving with corrections
PET/MRI scanners have great potential because they combine the strengths of two different systems. Previous problems resulting from respective, mutually exclusive physical effects of both procedures have been resolved. Now these scanners are being introduced to the hospital and assist in the detection of the position and spread of tumours as well as their metabolic activity, says Dr Harald H…
Article • Cold plasma
Treatment out of a power socket
Electricity is not the only thing that should come out of an electrical socket; ideally so should cold atmospheric plasma, according to Dr Georg Daeschlein, at the Dermatology Department, University of Greifswald, who has investigated its medical properties for years. Report: Ralf Mateblowski
