Artificial pancreas

Two small randomised trials published on bmj.com suggest that closed loop insulin delivery (also referred to as an artificial pancreas) may improve overnight blood glucose control and reduce the risk of nocturnal hypoglycaemia in adults with type 1 diabetes.

Article • PSA

A two-step biomarker approach for prostate cancer

Prostate cancer is the most frequently diagnosed cancer in males in developed countries and the sixth leading cause of cancer death worldwide. One reason for the increase in diagnosis is the widespread uptake of the prostate-specific antigen (PSA) test, capable of detecting slow growing cancers that might otherwise go undetected.

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Article • Medical research

Pharmacogenetics - Researchers focus on customised medication for patient groups

In the first month of 2011, the Centre for Pharmacogenetics and Pharmacogenomics at the Paracelsus Private Medical University in Salzburg, Austria, officially opened its doors. Why have pharmacogenetics and pharmacogenomics so increasingly important in medical research? We asked the head of the new research centre, Professor Markus Paulmichl.

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Antibiotic resistance spreads rapidly between bacteria

The part of bacterial DNA that often carries antibiotic resistance is a master at moving between different types of bacteria and adapting to widely differing bacterial species, shows a study made by a research team at the University of Gothenburg in cooperation with Chalmers University of Technology. The results are published in an article in the scientific journal Nature Communications.

Clear perspectives for medical technology

The German Medical Technology Association BVMed advocates for clear perspectives for medical technology innovations. "There is a need for a common strategic positioning of industry, science, and politics on research, development, and innovation in medical technology in Germany , states BVMed chairman Dr. Meinrad Lugan in the newly published Annual Report 2010/11.

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Anything but standard

Although paediatric laboratory medicine and clinical chemistry is a well and long established scientific field, it is still a challenging one with its own special problems, as Dr Massimiliano Cantinotti, Paediatric Cardiologist Consultant at Fondazione G Monasterio, National Research Institute, Massa, Italy, well knows.

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Integration to combat diabetes

To face the national and worldwide increase in diabetes mellitus cases, the German Federal Ministry of Education and Research initiated the foundation of the German Centre for Diabetes Research (DZD), aiming to improve basic research, prevention, diagnostic and therapy of diabetes. Inaugurated in Berlin a few months ago, the centre has five strategic partners.

Oxford’s new centre for science entrepreneurs

UK – A partly refurbished building in central Oxford is opening to provide space for science entrepreneurs. Science Oxford, a charity that supports education and business in the city, ultimately aims to demolish the building to create a science-focused public building to showcase new technological innovation from the Oxford area.

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The future of the pharmaceutical industry

The closure of Pfizer’s Sandwich Lab is part of a long-term decline in drug development, a trend that has been affecting all major UK pharmaceutical multinationals. Big pharmaceutical companies have been downsizing, outsourcing and merging in an attempts to find an innovation strategy that will keep their pipelines filled with new, potentially profitable products.

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European cancer mortality predictions for the year 2011

There will be nearly 1.3 million deaths from cancer in Europe in 2011 according to predictions from a study published in the cancer journal, Annals of Oncology. The estimates, which have been reached after researchers used for the first time in Europe a new mathematical model for predicting cancer mortality, show a fall in overall cancer death rates for both men and women when compared to 2007.

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Plasma therapy: an alternative to antibiotics?

Cold plasma jets could be a safe, effective alternative to antibiotics to treat multi-drug resistant infections, says a study published this week in the January issue of the Journal of Medical Microbiology. The team of Russian and German researchers showed that a ten-minute treatment with low-temperature plasma was not only able to kill drug-resistant bacteria causing wound infections in rats but…

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Improving biochemical substances research

Chemical substances can bring miracles: they kill bacteria, prevent viral multiplication or stop cancer cell growth. Thus they offer a huge reservoir of potential drugs. However, seeking substances and their biological effects is a mammoth task and cannot be undertaken alone. The Preparatory Phase Project EU-OPENSCREEN (European Infrastructure of Open Screening Platforms for Chemical Biology) was…

Liver Cancer in Cirrhotic Patients Effectively Treated with Radiofrequency Ablation

Researchers from Italy determined that radiofrequency ablation (RFA) is a safe and effective therapy for managing hepatocellular carcinoma (HCC) in cirrhotic patients. The high repeatability of RFA is advantageous in controlling recurrences of cancerous tumors in the liver. Results of this 10-year retrospective study are available in the January 2011 issue of Hepatology, a journal published by…

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Is Santa Claus toxic?

The exact location of Santa’s Workshop has long been kept secret, but one thing every child knows is that he lives somewhere up by the North Pole. It’s a place that has seen great changes in recent years with melting sea ice and warmer summer temperatures attributed to global warming.But climate change isn’t the only bad news facing the world’s favorite jolly old elf: research from the…

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