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Sponsored • Innovative design

Maximum power for efficient processes

Vacuum systems are the best solution for the safe disposal of biological liquids in laboratories. A coated membrane, special valves and a high gas tightness offer the safe and sustainable disposal of biological liquid waste. The latest generation of Axonlab's universal mini vacuum extraction system was developed in a development period of around 18 months. The patented product combines years of…

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Sponsored • Minimising infection risk

Drying in endoscope reprocessing: Essential to patient safety

In practice, the drying of the endoscope is often underestimated and therefore a possible pitfall for hygiene and reprocessing steps. As the importance of endoscopic retrograde cholangio-pancreatography (ERCP) procedures and their impact on patients’ lives remains unwavering, the medical community is continuously looking for ways to improve this field of expertise. What better way to learn more…

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News • Deep learning vs. AML

AI-driven blood cell classification supports leukemia diagnosis

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood samples from patients suffering from acute myeloid leukemia (AML). Their proof of concept study paves the way for an automated, standardized and on-hand sample analysis in the near future. The paper was…

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News • Presented at the NCRI cancer conference

Simple blood test for early detection of breast cancer

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells, according to new research presented at the 2019 NCRI Cancer Conference. Cancer cells produce proteins called antigens that trigger the body to make antibodies against them – autoantibodies. Researchers…

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Sponsored • Product of the Month

Using safety products reduces the risk of needlestick injuries

If a health sector employee falls ill with a bloodborne illness, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with an NSI, is one of the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Don’t take the dangers posed by NSI lightly: get…

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Interview • Chronic inflammations

GATA-3: 'Switching off' allergies and asthma

Chronic inflammatory diseases, such as allergies and asthma, are not only an acute problem but also a major research and prevention challenge. We spoke with Professor Harald Renz, Director of the Institute for Laboratory Medicine at the University Hospital Gießen/Marburg, Germany, and discussed the major reason for increases in the number of these widespread diseases.

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News • MRSA & Co.

Test to detect antibiotic resistance in less than 45 minutes

Scientists from Scotland are developing a low cost, rapid diagnostic sensor test which aims to show the susceptibility of bacteria to antibiotics within 45 minutes. Laboratory testing of samples can take up to two days and the new test aims to allow doctors to be able to prescribe the correct antibiotic to a patient for an infection more quickly. In a research paper published in the journal…

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Sponsored • Lab medicine

Four perspectives on preanalytics and patient safety

BD participated in the 5th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) conference on preanalytical phase in Zagreb, Croatia 22–23 March 2019. At the conference, we met Mr Steve McManus, Prof Ana-Maria Simundic, EFLM conference chair, Prof Mario Plebani and Dr Alexander von Meyer, member of the EFLM conference scientific committee. Prof Simundic and Dr von Meyer…

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Article • Laboratory economics

Lab services: Don’t cut the cost!

In recent years, whenever the German media reported on laboratory medicine, questions consistently arose: ‘How can excessive costs for lab services be cut?’ and ‘How could money saved be distributed among other medical specialists and general medicine practitioners (GPs)?’ The questions are myopic in their failure to address two important aspects of laboratory medicine – its…

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News • Cognitive chemical manufacturing

‘Lab-bot’ could revolutionise hunt for cancer drugs

A robot-controlled laboratory where decisions are made by artificial intelligence will change the way new drugs are discovered, says a leading researcher. The engineer leading a project to develop a prototype "lab-bot" says it will reduce the time it takes to identify and synthesise molecules for new medicines – a process that can take years as scientists refine the shape and property…

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Article • Combatting nosocomial infections

A&E Staphylococci POCT

Martin Möckel and Dorothee Riedlinger, from the Charité Medical University Berlin, Emergency and Acute Medicine Campus Virchow-Klinikum, and Campus Charité-Mitte report on POCT testing in the A&E Department to screen for Staphylococcus aureus colonisation of the nose or throat. People colonised with Staphylococci are at increased risk of developing a nosocomial, i.e. hospital acquired…

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Article • Disinfection

Why rigorous hygiene practices are vital

Nosocomial infections present enormous challenges for medical facilities, involving huge hygiene efforts from staff, on patients as well as medical and non-medical products. At MedtecLIVE 2019, in Nuremberg, Susanne Harpel (Dipl. Ing), Deputy Head of the Institute for Hygiene and Environmental Medicine at Giessen/Marburg Univer­sity Hospital, presented desirable contamination efforts during the…

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Article • Workforce challenges

Pathologists will hold a pivotal role

Amid ever-growing demand for services, significant challenges face the pathology workforce in the years ahead but – there are also good opportunities. With advances in technology and the advent of artificial intelligence as a decision-making support tool, Professor Jo Martin, President Royal College of Pathologists (RCPath) in the UK, believes there remain opportunities for pathology to play a…

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Sponsored • Instruction for Use

Infection risk mitigation by simplified IFUs

Duodenoscopes have been long recognized to require precise execution of reprocessing instructions to properly clean and disinfect. According to Beilenhoff, et al. (2018), it is crucial to follow the manufacturer’s Instructions for Use (“IFU”) at all times to make sure the duodenoscopes are properly cleaned. Yet, IFUs are not always easy to follow.

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News • A STAMP with high value

New tech makes biopsies less invasive, more informative

A team of researchers has developed a novel technology that could sensitively and accurately detect and classify cancer cells, as well as determine the disease aggressiveness from the least invasive biopsies. With this new technology called STAMP (Sequence-Topology Assembly for Multiplexed Profiling), comprehensive disease information can be obtained faster, at a much earlier stage of the…

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News • t-MALDI-2

Dual-beam laser mass spectrometry gives unique insights

Cells are the basic building blocks of life – and, as such, they have been the object of intense study since the invention of the optical microscope in the 17th century. The development of mass spectrometry (MS) methods – those which define the chemical composition of cells – represented a further milestone for research in the field of cell biology. In the latest issue of the journal Nature…

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News • Feasibility study

Liquid biopsy to complement early breast cancer screening

Investigators from the Biomedical Research Institute of Malaga [(IBIMA)-CIMES-UMA, Malaga Spain] and collaborators have published the first pilot study to examine the use of a non-invasive liquid biopsy in early diagnosis of breast cancer. This study was unique in that the ctDNA analyses was performed before any invasive diagnostic procedure or treatment. To achieve their goal, the researchers…

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Sponsored • Immunoassay

The quantitative measurement of cardiac troponin I concentration

Pathfast hs-cTnI is a chemi-luminescent enzyme immunoassay (CLEIA) for the quantitative measurement of cardiac troponin I (cTnI) concentration in whole blood or plasma at the point-of-care (POC). Reagents are single use in all-in-one cartridges and up to six tests in parallel can be analysed,’ the manufacturer Mitsubishi reports. ‘Low concentrations of cTnI can be analysed by using high…

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Article • Methods, quality assurance, commercial providers issues

Molecular testing takes a huge leap

In terms of success in revolutionary cancer treatment, molecular genetic examination procedures have developed immensely over recent years. They now range from conventional polymerase chain reactions (PCR) or fluorescence-in-situ hybridisation (FISH) to Next Generation Sequencing (NGS) with analysis of the entire exome or genome (Whole-Exome, WES or Whole-Genome, WGS) and of the transcriptome…

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News • Mortality risk

A new biomarker to predict your lifespan?

Fourteen metabolic biomarkers can predict long term mortality in individuals helping to determine life expectancy in general populations, a new study in the journal Nature Communications reports. In the largest study of its kind, researchers from Leiden University Medical Center in the Netherlands and the University of Surrey investigated predictors of long-term mortality risk. Current predictors…

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