A novel study published in AACC’s The Journal of Applied Laboratory Medicine shows that delaying the second Covid-19 vaccine dose for more than the recommended 3-4 weeks results in higher antibody levels. This finding could play a vital role in shaping vaccine distribution strategies that increase access to the vaccine around the globe.
Roche announced the decision to discontinue dosing in the Phase III GENERATION HD1 study of tominersen (previously IONIS-HTTRx and RG6042) in manifest Huntington’s disease (HD). The decision was based on the results of a pre-planned review of the data from the Phase III study conducted by an unblinded Independent Data Monitoring Committee (iDMC). The iDMC made its recommendation based on the…
A new blockchain-based data analysis app aims to drive collaboration and insights across clinical trials. The tool, developed by software company Clintex, is designed to boost trial efficiency, help drive down the cost of new medicines and expediting their delivery to patients.
GreenBone Ortho, a company specialising in bone regeneration, announces that it has achieved its aim of recruiting 15 patients into the GreenBRIC study. GreenBRIC study is a prospective, open label, single-arm, First-in-Human clinical investigation, in male and female patients, aged between 18 and 70 years, undergoing surgery to correct bone defects using GreenBone Implant, specifically for iliac…
Cancer informatics and digital pathology provider Inspirata announced that King’s Health Partners ECMC and Guy’s and St Thomas’ NHS Foundation Trust will pilot its Trial Navigator software as part of an evaluation the organisations are conducting into how artificial intelligence based automation can improve the identification and efficiency of matching patients with cancer to early phase…
Patients who experience long Covid have reported more than 200 symptoms across 10 organ systems, in the largest international study of ‘long-haulers’ to date, led by scientists at University College London together with a patient-led research collaborative.
Although the coronavirus affects men and women differently, the vast majority of clinical trials do not mention sex/gender, a new analysis of 4,420 studies concludes. Ultimately, it can influence the treatment negatively. The meta analysis is published in Nature Communications. According to the new research, only 4 percent of 4,420 registered studies explicitly plan to address sex and gender in…
A European comparative study has evaluated national organ donation policies in seven countries from an ethical perspective. For the first time, knowledge and attitudes towards organ donation regulations in different European countries were investigated in combination. The study was published in the journal PLOSone.
Rapid tests effectively broke Covid-19 infection chains in spring 2021. This is shown by a model developed by researchers of the ECONtribute: Markets & Public Policy Cluster of Excellence of the Universities of Bonn and Cologne, the Collaborative Research Center Transregio 224 EPoS of the Universities of Bonn and Mannheim, and the Institute for the Study of Labor (IZA). According to the…
In noisy environments, it is difficult for hearing aid or hearing implant users to understand their conversational partner because current audio processors still have difficulty focusing on specific sound sources. In a feasibility study, researchers from the Hearing Research Laboratory at the University of Bern and the Inselspital are now suggesting that artificial intelligence (AI) could solve…
Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation – are completed more than 38 weeks from the time of diagnosis. The observational study, which included more than 28,000 breast cancer patients registered in the American National Cancer Database, is…
Aerosol generated by playing woodwind and brass instruments is less than that produced when vocalising (speaking and singing) and is no different than a person breathing, new research has found. The findings could be crucial to developing a roadmap for lifting Covid-19 restrictions in the performing arts, which have been significantly restricted since the start of the pandemic.
A study involving virtual rather than real patients was as effective in evaluating a medical device used to treat brain aneurysms, according to new research. The findings are proof of concept for what are called in-silico trials, where instead of recruiting people to a real-life clinical trial, researchers build digital simulations of patient groups, loosely akin to the way virtual…
Mining the world's most comprehensive drug repurposing collection for Covid-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.
Cities harbour a dangerous cocktail of environmental stressors which politicians must tackle to save lives and preserve health. That’s the conclusion of a paper published in European Heart Journal, a journal of the European Society of Cardiology (ESC). “By 2050, three in four people will live in cities, where up to 80% of energy is consumed and 70% of greenhouse gases are emitted,” said…
A new study from the University of Surrey and University College London has revealed that treatment for heart attacks could be improved thanks to a novel method of evaluating heart function using contrast-based MRI scans. According to the British Heart Foundation, heart and circulatory diseases cause more than a quarter (27 per cent) of all deaths in the UK, which equates to more than 160,000…
In Sweden, there are over 2 million legally owned firearms. At the same time, up to 150,000 people live with a diagnosis of dementia. In an aging society such as Sweden, legislators will face challenges in gun ownership. A new registry-based observational study by researchers from NVS, Karolinska Institutet, published in the Journal of Alzheimer’s Disease shows a need for strategies for this…
A large study from Denmark and Norway published by The BMJ sheds more light on the risk of rare blood clots in adults receiving their first dose of the Oxford-AstraZeneca Covid-19 vaccine. The findings show slightly increased rates of vein blood clots including clots in the veins of the brain, compared with expected rates in the general population. However, the researchers stress that the risk of…
Women and men are different – nobody would argue with this statement. However, in medicine, gender plays a subordinate role. Neither research, prevention nor therapy adequately reflect this difference. “This is no longer acceptable,” says internist and cardiologist Prof. Dr. Vera Regitz-Zagrosek.
In just the last two years, artificial intelligence has become embedded in scores of medical devices that offer advice to ER doctors, cardiologists, oncologists, and countless other health care providers. But how much do either regulators or doctors really know about the accuracy of these tools? A new study led by researchers at Stanford, some of whom are themselves developing devices, suggests…
Researchers running the Com-Cov study, launched in February to investigate alternating doses of the Oxford-AstraZeneca vaccine and the Pfizer vaccine, announce that the programme will be extended to include the Moderna and Novavax vaccines in a new study.
Does overcoming a SARS-CoV-2 infection protect against reinfection? The “Rhineland Study”, a population-based study conducted by DZNE in the Bonn area, is now providing new findings in this regard. Blood samples taken last year indicate that an important component of immunity – the levels of specific neutralizing antibodies against the coronavirus - had dropped in most of the study…
Body composition information derived from routine chest CTs can provide important information on the overall health of people with chronic obstructive pulmonary disease (COPD), including their risk of all-cause mortality. This is the result of a new study, published in Radiology. COPD is a group of chronic, progressive lung diseases that affect about 30 million people in the United States alone.…
Medical technology company iCAD, Inc. announced that ProFound AI for 2D Mammography might notably reduce the risk of interval breast cancer, according to a new retrospective analysis. The aim of the study was to determine if adding AI to reading mammography as a supportive tool may help in decreasing the interval cancer rate in population-based organized mammography screening programs in Germany.
People discharged from hospital after Covid-19 appear to have increased risks of diseases across multiple organs and nearly a third are readmitted to hospital in the following months, according to a new study co-led by researchers at University College London. The study, published in The BMJ, looked at nearly 50,000 people who were discharged from hospital by August last year and compared them to…
