In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
BRAF is a protein that plays an important part in the transmission of growth signals. In a mutated state it can lead to uncontrolled cell growth. Around every second malignant melanoma – the deadliest and most aggressive form of skin cancer – has a certain mutation of the BRAF gene.
Faster assay for targeted chemotherapy's success against deadly liver cancer saves lives, and could speed lifesaving switch to alternative drug therapies for well-known pancreatic cancer.
The world’s first gene cancer therapy study of an innovative oral vaccine is underway at the Surgical Clinic of Heidelberg University Hospital.
Reliable Cancer Therapies (RCT) celebrates the first anniversary of its website in style. The Swiss non-for-profit organization has completed comprehensive guides for cancer patients and their relatives, which are now available on its website.
Although powerful, new, targeted treatments are regularly introduced to cancer clinics, choices for the first-line treatment of invasive breast cancer normally lie between preventive surgery and chemotherapy. A recent American study used genomic prediction combining multiple signatures to determine outcomes to standard chemotherapy.
A multi-centre French study is demonstrating that a four-minute ultrasound scan using a contrast agent can be performed after the first month of treatment and provide quantitative proof of whether a tumour is responding to the therapy.
Agenzia Provinciale Per la Protonterapia (ATreP) has signed a contract with Ion Beam Applications S.A. (IBA), based in Luvain-La-Neuve, Belgium, for the installation of a proton therapy centre in a new hospital planned for Trento. Over the next 15 years, IBA will provide the construction, installation and technical operation of this the first gantry-equipped proton therapy-dedicated centre in…
That wait time might be shortened for patients with soft-tissue sarcomas thanks to new research, from the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles (UCLA), demonstrating that PET/CT can be used as early as one week after a single treatment cycle to determine whether the drugs are killing the cancer. Researchers made another surprising discovery—some tumors…
A global vaccination programme against human papilloma virus (HPV), to include boys as well as girls, could lead to eradication of the virus and virtual disappearance of cervical cancer, according to Nobel Prize winner, Professor Emeritus Harald zur Hausen (University of California, San Diego) after recently delivering a keynote lecture at the 16th International Meeting of the European Society of…
Pain is the most common symptom of any illness thus having an alerting function to evoke protective responses. If tissue damage has happened as a consequence of surgery, obstruction, injuries, or cancer a cascade of changes in the peripheral and central nervous system occurs leading to physical inactivation, an increase of morbidity thus delaying hospital stay and treatment costs.
It is very difficult to predict whether a cancer drug will help an individual patient: only around one third of drugs will work directly in a given patient. Researchers at the Heinz Nixdorf Chair for Medical Electronics at the Technische Universitaet Muenchen (TUM) have developed a new test process for cancer drugs. With the help of microchips, they can establish in the laboratory whether a…
Radionuclide therapy has been rapidly developing for the last 20 years, due to the availability of new carrier molecules and radionuclides. For some years the clinical efficacy has been modest with a low percentage of objective responses and no survival benefit because, most often, the patients had large tumor burden.
A global vaccination programme against human papilloma virus (HPV), to include boys as well as girls, could lead to eradication of the virus and virtual disappearance of cervical cancer, predicted Nobel Prize winner, Professor Harald zur Hausen, after delivering the key-note lecture at the 16th International Meeting of the European Society of Gynaecological Oncology (ESGO) in Belgrade, Serbia,…
Colorectal cancer (CRC) jointly describes cancers of the colon and rectum. Worldwide, CRCs are among the most common cancers. In Europe and the USA the occurrence of CRCs are considerably higher than in Africa and Asia.
Positive CB7630 (Abiraterone Acetate) Phase II Data was presented at the ASCO Annual Meeting in Chicago this May/June, Cougar Biotechnology Inc, a development stage biopharmaceutical firm with a specific focus on oncology. In mid-July, Johnson & Johnson announced its acquisition of Cougar, which is now working with Ortho Biotech Oncology Research & Development, a division of the J&J firm Centocor…
Researchers around the globe are studying whether a genomic test, developed with micro-array technology, is superior to traditional methods in assessing aggressive breast cancer, and therefore could spare a considerable percentage of women from the onslaught of chemotherapy The Breast International Group (BIG) in Brussels, Belgium, manages TRANSBIG, an international network created to avoid…
Completion of a Phase I clinical trial has demonstrated the great promise of a completely new type of cancer treatment, according to results announced this June in The New England Journal of Medicine by scientists at the Institute of Cancer Research (ICR) and the Royal Marsden Hospital in the United Kingdom, working with pharma firm AstraZeneca.
There is a profound difference between the complexity of cosmetic surgery or organ transplant procedures, for example, and other operations. Whilst procedures such as hair transplants or eyelid surgery present an alteration to the owner's body composition and changes to the patient's outlook, those changes were desired and planned for, in the hope that something marvellous will result and so…
An interdisciplinary team of researchers at Brigham and Women's Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors by using specially engineered nanoparticles that can inhibit a signaling pathway and deliver a higher concentration of medication to the specific area.
17-21 March Stockholm Sweden
Working in partnership to integrate diagnostic imaging, laboratory diagnostics and IT, the Hospital Clinic Barcelona and Siemens Healthcare aim to develop innovative systems to prevent, treat and follow-up for various pathologies.
Olwen Glynn Owen reports on MammaPrint, a test that pinpoints the risk of breast cancer recurrence from the primary tumour's genetic make-up. Women with breast cancer tumours under
Tumour ablation - and Radiofrequency (RF) ablation in particular - is getting more and more important in oncology. The therapy option offers benefits in terms of costs, ease of set-up and flexibility so that experts see the need to expand the applications of it.
Two thirds of cancer patients receive little or no information about the survival benefits of having palliative chemotherapy before making a decision about treatment, according to a study published on the British Medical Journal website.