The new national Precision Omics Initiative Sweden (PROMISE) aims to generate and integrate extensive molecular data to create a model for precision medicine implementation for Sweden.
As of May 1st, Maartje Huijbers holds the position of vice dean of research, a new position within the Leiden University Medical Center (LUMC). Huijbers is associate professor and research group leader in the Department of Human Genetics and the Department of Neurology. She will combine her work as a scientist with the position of vice dean.
A research project investigating the genetics and health of volunteers from the Hebrides, Shetland or Orkney shows how distinct genetic populations can benefit from tailored screening programmes.
Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.
Researchers have published findings that show the genetic structure of the heart’s shape may offer new insights into individual heart health.
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
A European research team has now shown that dietary measures are more effective in IBS patients with defects in carbohydrate digestion genes than in those without these changes.
A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.
The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.
Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.
A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.
Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.
Researchers discovered a gene that might be a key factor in the progression of Huntington’s disease in organoids. The gene may contribute to brain abnormalities much earlier than previously thought.
Enter symptoms into ChatGPT, receive an accurate diagnosis? Research reveals that LLM AI models are not quite there yet, struggling to identify genetic conditions from patient-written descriptions.
Can a look at a patient's DNA predict progress of their colorectal cancer? Findings from a new study could lead to improved possibilities for individualised therapies.
Using genomic sequencing data, researchers have created personalised simulations of individual patients that can quantify the impact of genetic mutations on cancer cell behaviour.
Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.
Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.
Could the 'gene scissors' CRISPR be used to make resistant bacteria susceptible to first-line antibiotics again? According to new reseach, yes – but the experts also point out serious caveats.
Primary ciliary dyskinesia (PCD) is a rare inherited multi-organ condition, which can lead to inflammation of the airways and infections. Now, scientists have found what causes PCD.
A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
Much like joints or blood vessels, the brain can be affected by calcifications. This can lead to neurodegenerative disease, but is not well studied. Now, researchers from Norway identified a gene that provides new insights.
Scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.
Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.
