It's an important milestone for gene editing technology: a novel treatment for sickle cell disease utilizing CRISPR-Cas9, has now received FDA approval – a first for this type of therapy.
When a woman becomes pregnant, sometimes her pre-existing rheumatoid arthritis will 'magically' go away. In others, the condition becomes even worse. Now, US researchers may have found an explanation.
Swiss scientists report that they have developed a gene therapy that was proven in mice to stimulate nerve regrowth across spinal cord injuries and guide nerves to reconnect to their natural targets.
A genetic test for BRCA1 or BRCA2 gene mutations may drive women to undergo breast cancer surgery, even though their risk might not even be drastically affected by this, a new study finds.
ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia: beta thalassaemia and sickle cell anaemia.
Scientists have developed a tool to create a digital replica of an individual's heart, which could inform the diagnosis and treatment of cardiovascular diseases.
Scientists have designed an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery — critical information that can guide treatment decisions.
By using genetic data on multiple traits from people of non-European ancestry, scientists have improved the accuracy of polygenic scores in predicting disease risk for all.
Genomic sequencing panels as part of personalised cancer treatment have been found to only benefit one in 20 patients they are currently used for, according to a study by CNIO.
New research suggests that combining blood biomarkers with genomic information more accurately, cost-effectively predicts the risk of developing diseases.
The accuracy of prostate-specific antigen (PSA) screening can be improved by including genetic factors that cause changes in PSA levels not associated with cancer, according to a multi-center study.
Gene alterations in biliary tract cancer offer potential targets for current or future precision therapies. This is demonstrated by a new study from Vienna.
Tumors sometimes seem to take on a life of their own, with cancer genes “striking out” in ring shapes. An international research team has new insights into this phenomenon.
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
Scientists at the University of Applied Sciences Krems (IMC Krems) show that CRISPR-Cas9 can also be used to inhibit viruses such as adenoviruses in cell cultures.
Johns Hopkins researchers, along with colleagues in Italy, have published a study that looks into the genetic mechanisms behind the development of schizophrenia.
Genes are full of clues about a person's health and might also show the way for stroke recovery.
Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study in the U.K..
An international coalition of biomedical researchers has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.
Testing for genetic mutations in urine can detect bladder cancer years before the disease shows clinical symptoms, new research has shown - reaching more than a decade for the most common cancer type.
According to an international group of researchers led by Leiden University Medical Center (LUMC), patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
A new approach on the genetic tool CRISPR-Cas9 could reduce the risk of unwanted mutation, making it safer for use in humans, Dutch researchers have found.
New advanced therapies can alleviate or cure chronic diseases. But medical progress, such as the gene editing tool CRISPR, raises the question of how rights should be protected and balanced.
An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.
An international team highlights the importance of localising BRCA1 and BRCA2 gene mutations for the treatment of ovarian cancer.