News • Targeted therapy
Biliary duct cancer: the future of precision oncology
Gene alterations in biliary tract cancer offer potential targets for current or future precision therapies. This is demonstrated by a new study from Vienna.
Genetics
News • Independent genes
Cancer: Study sheds light on mysterious DNA rings
Tumors sometimes seem to take on a life of their own, with cancer genes “striking out” in ring shapes. An international research team has new insights into this phenomenon.
News • Oncology & Biomedical Technology
New treatment option in bone cancer: gene therapy combined with chemotherapy
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
News • Genetics & Viruses
"Gene scissors" in human cells inhibit viral infections
Scientists at the University of Applied Sciences Krems (IMC Krems) show that CRISPR-Cas9 can also be used to inhibit viruses such as adenoviruses in cell cultures.
News • Genetics & Neuroscience
Research investigates the convergence of schizophrenia risk genes in brain coexpression networks
Johns Hopkins researchers, along with colleagues in Italy, have published a study that looks into the genetic mechanisms behind the development of schizophrenia.
News • Genetics & Neuroscience
Improvement of stroke diagnosis and treatment through specific genes
Genes are full of clues about a person's health and might also show the way for stroke recovery.
News • Genetic diseases
Study sheds light on causes of rare genetic diseases in 5,500 people
Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study in the U.K..
News • Prevention of blood cancer
Research identifies new target that may prevent blood cancer
An international coalition of biomedical researchers has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.
News • Up to 12 year in advance
Urine gene test can predict bladder cancer years before diagnosis
Testing for genetic mutations in urine can detect bladder cancer years before the disease shows clinical symptoms, new research has shown - reaching more than a decade for the most common cancer type.
News • Personalised medicine
DNA-matching medication reduces side effects by 30%
According to an international group of researchers led by Leiden University Medical Center (LUMC), patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
News • Researchers improve DNA cut-and-paste technique
Increasing safety for "gene scissors" CRISPR-Cas9
A new approach on the genetic tool CRISPR-Cas9 could reduce the risk of unwanted mutation, making it safer for use in humans, Dutch researchers have found.
News • Potential and pitfalls of CRISPR
Gene therapies raise difficult legal and ethical questions
New advanced therapies can alleviate or cure chronic diseases. But medical progress, such as the gene editing tool CRISPR, raises the question of how rights should be protected and balanced.
News • Driving genes of AMR in focus
Tracking the global spread of antimicrobial resistance
An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.
News • Precision medicine
Localising BRCA gene mutations to better treat ovarian cancer
An international team highlights the importance of localising BRCA1 and BRCA2 gene mutations for the treatment of ovarian cancer.
News • CLL types with distinct biological and clinical features
Whole genome profiling reveals new leukaemia subgroups
A collaborative study has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukaemia (CLL), and associated these with clinical outcomes.
News • Researchers develop noninvasive approach
FUSIN: Delivering gene therapy with ultrasound
Treatment of central nervous system diseases and tumors is often hindered by the blood-brain barrier. A new method aims to overcome this obstacle using focused ultrasound intranasal delivery (FUSIN).
News • Infection control
Legionnaire's disease: genetic analysis key to understanding risk
Routine sampling of water supplies and genomic sequencing of Legionella bacteria could play a key role in identifying the source of Legionnaires’ disease outbreaks, research suggests.
News • How cancer spreads
Cancer metastasis: Breakthrough to lead to better treatments
Cambridge scientists have discovered that cancer cells ‘hijack’ a process used by healthy cells to spread around the body, completely changing current ways of thinking around cancer metastasis.
News • Conference attendance
New lab systems for virology showcased at ESCV 2022
Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.
Video • Clonal somatic mutations
How does cancer grow? Genetic mapping gives new insight
Researchers from the UK and Sweden have found that individual prostate tumours contain a previously unknown range of genetic variation.
News • Genome instability
Gene editing via CRISPR/Cas9 can lead to cell toxicity
Researchers identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches.
News • Cardiomyopathy research
Genetic defects can cause heart failure
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
News • Novel disease therapies
"Soft” CRISPR may offer fix for genetic defects
A new approach makes use of natural DNA repair machinery and provides a foundation for novel gene therapy strategies with the potential to cure a large spectrum of genetic diseases.
News • Not just for bitcoin
Blockchain can secure and store genomes
Blockchain is a digital technology that allows a secure and decentralized record of transactions. Now, researchers leveraged blockchain to give individuals control of their own genomes.
News • Genetics research
Chromosomes: How the 'extra X factor' is putting men at risk
Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis.
