Cancer

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News • Brain disorder

Using ultrasound to achieve permeability of blood vessels

CarThera, a French company based at the Brain and Spine Institute (ICM), that designs and develops innovative ultrasound-based medical devices to treat brain disorders, announces the publication on initial successes in disrupting the blood-brain barrier (BBB) with the use of ultrasound. This has been achieved in association with teams from the Assistance Publique-Hôpitaux de Paris (the Greater…

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More light on cancer

The group of Russian and French researchers, with the participation of scientists from the Lomonosov Moscow State University, has succeeded to synthesize nanoparticles of ultrapure silicon, which exhibited the property of efficient photoluminescence, i.e., secondary light emission after photoexcitation. These particles were able to easily penetrate into cancer cells and it allowed to use them as…

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News • Targeted treatments

Gene therapy against brain cancer

A team from the International School for Advanced Studies (SISSA) in Trieste has obtained very promising results by applying gene therapy to glioblastoma. Tests in vitro and in vivo on mice provided very clear-cut results, and modelling demonstrates that the treatment targets at least six different points of tumour metabolism. Gene therapy, a technique that selectively attacks a tumour, might…

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News • Iso-acoustic focusing

Ultrasound method increases awareness about cancer cells

In brief, the new method involves exposing cells to ultrasound when they flow through a so-called micro-channel inside a chip. The individual cells are separated in the acoustic field and by studying the cells’ lateral movement at the end of the channel it is possible to identify the acoustic properties of the cells. Conversely, if you know the cells’ acoustic characteristics, you can detect…

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News • GLINT project

Using sugar to detect cancer: a game changer for cancer screening

Cancer accounts for 13 percent of all deaths worldwide and despite recent medical improvements remains one of the most deadly diseases in the world. Early detection, usually through advanced medical imaging, is crucial as it increases the chances of survival and the potential for full recovery. The EU-funded project GlucoCEST Imaging of Neoplastic Tumours (GLINT) will develop an innovative…

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Article • Datasets

Benefits from The Cancer Genome Atlas

Last year, scientists at the University of California San Francisco (UCSF) revealed that by measuring the proportion of both immune and cancerous cells in tumours, or ‘tumour purity,’ clinicians could more precisely predict the success of certain precision therapies. A key aspect of the discovery was access to over 10,000 samples constituting 21 different cancers.

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News • E. coli

Using harmless bacteria to fight cancer

Several bacterial species have pledged promise in fighting tumors. However, most of them are pathogens. In order to use them as a weapon against cancer and other diseases in humans, researchers must find a balance between their therapeutic aggressiveness and safety for the patient. To overcome this problem, researchers at the Helmholtz Centre for Infection Research (HZI) have shifted their focus…

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News • Oncology

How printing a 3-D skull helped save a real one

What started as a stuffy-nose and mild cold symptoms for 15-year-old Parker Turchan led to a far more serious diagnosis: a rare type of tumor in his nose and sinuses that extended through his skull near his brain. “He had always been a healthy kid, so we never imagined he had a tumor,” said Parker’s father, Karl. “We didn’t even know you could get a tumor in the back of your nose.”

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News • PIK3CA

Cancer drug could treat blood vessel deformities

A drug currently being trialled in cancer patients could also be used to treat an often incurable condition that can cause painful blood vessel overgrowths inside the skin, finds new research in mice led by UCL, Memorial Sloan Kettering (MSK) Cancer Center in New York and the Bellvitge Biomedical Research Institute (IDIBELL) in Barcelona.

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News • Head and neck

Imaging scans track down persistent cancer cells

Head and neck cancer patients may no longer have to undergo invasive post-treatment surgery to remove remaining cancer cells, as research shows that innovative scanning-led surveillance can help identify the need for, and guidance of, neck dissection. The study from the Universities of Birmingham and Warwick and University Hospitals Coventry and Warwickshire used advanced imaging to identify…

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Article • Ovarian cancer

The story of the silent killer

Andrea G. Rockall, Consultant Radiologist at the Royal Marsden Hospital and Visiting Professor of Radiology at Imperial College in London, delivered the prestigious Wilhelm Conrad Röntgen Honorary Lecture at ECR 2016 on ‘Imaging the invisible killer: towards personalisation of ovarian cancer care’.

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News • Oncology

Pancreatic cancer: Enzyme renders tumors resistant

Scientists at the German Cancer Research Center (DKFZ) and the Stem Cell Institute HI-STEM in Heidelberg have discovered the reason why some pancreatic tumors are so resistant to treatment. They have found that these tumor cells produce larger quantities of an enzyme that usually occurs in the liver and degrades many drugs. If this enzyme is blocked, the cancer cells become sensitive towards…

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News • Fighting cancer

Stopping tumour cells killing surrounding tissue

Tumours kill off surrounding cells to make room to grow, according to new research from the University of Cambridge. Although the study was carried out using fruit flies, its findings suggest that drugs to prevent, rather than encourage, cell death might be effective at fighting cancer – contrary to how many of the current chemotherapy drugs work.

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Cancer cells poised for growth when opportunity knocks

Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.

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