Blood

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Article • Diabetes

Microneedles: Nano-sized, huge impact

Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a patient also comes with several drawbacks. By downscaling the to micrometer-size, Japanese researchers open even more areas of application for needles, while bypassing some of the most important…

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Sponsored • DBS PEth analysis

Fully automated and hematoctrit corrected phosphatidylethanol analysis

The Swiss-based CAMAG DBS Laboratory in ­collaboration with the Institute of Forensic ­Medicine in Bern, Switzerland, has developed a novel approach for the fully automated analysis of the direct alcohol marker phosphatidylethanol (PEth) in dried blood spots (DBS). The use of a DBS autosampler with an embedded hematocrit (HCT) scanner combined with an LC-MS system permits analysis of large…

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News • Anemic alternatives

'Bloodless' transfusion could solve global blood shortage

Blood transfusions save lives, yet the precious fluid is in desperately short supply around the globe. But what if transfusions don’t always require blood? A new mathematical model of the body’s interacting physiological and biochemical processes – including blood vessel expansion, blood thickening and flow-rate changes in response to the transfusion of red blood cells – shows that…

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News • Rare liver disease

New test improves diagnosis of autoimmune hepatitis

Autoimmune hepatitis (AIH) is a chronic liver inflammation that is triggered by an immunological malfunction. In this case, the immune system falsely recognises the patient's own liver cells as "foreign to the body". The symptoms of this rare liver disease are unspecific, and the exact cause is not yet known. If left untreated, AIH can lead to abnormal scarring (fibrosis) of the liver,…

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News • DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…

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News • Blood poisoning

Sepsis: 5-country survey shows lack of public awareness

On World Sepsis Day, in vitro diagnostics company bioMérieux and the UK Sepsis Trust reveal the results of a survey conducted in Europe regarding knowledge and attitudes towards sepsis. The findings demonstrate the need to accelerate awareness and education of the general population about this life-threatening condition.

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