News • Equipment and technology fair
Labs Expo announces extensive and engaging programme
Registration is now open for the Labs Expo Laboratory Equipment and Technology Fair (March 19-20), the premier event in the laboratory industry in Poland.
Article • QC at AACC 2023
New risk-based quality control assessment for clinical labs
Juggling the cost of quality control (QC) resources versus the risk of testing error is a balancing act no clinical laboratory manager enjoys. It is an inexact process, itself prone to error, which can impact the operations of hospital labs and independent clinical testing companies. In the current resource-constrained healthcare environment, there is pressure to improve the cost effectiveness of…
News • Chemotherapy and cancer drugs
‘Heart-on-a-Chip’ to test cardiotoxicity of treatments
Chemotherapy can be toxic to heart cells. To help protect the hearts of cancer patients, Cedars-Sinai investigators have created a three-dimensional “heart-on-a-chip” to evaluate drug safety.
News • Mitosis profiling
AI tool helps grade cancer based on cell divisions
Ahead of World Cancer Day on 4 February, scientists are revealing a cutting-edge artificial intelligence (AI) tool designed to help grade cancer, by analysing cell division.
News • Accelerated sample analysis
Digital pathology cleared for use in cancer screening programmes
Digital pathology brings benefits for sample management and optimisation, lets pathologists work on samples remotely: The UK Government has now approved the use of the technique for cancer samples.
Article • Addressing an unmet need
MCED: a simple test for widespread early detection of cancer
Academic labs and biotech firms pioneer multi-cancer early detection with emerging technologies. Screening for multiple cancers with a simple blood or urinary draw could be a game-changer. Two research teams in particular have advanced the field.
News • Elimination of senescent tumour cells
Study: Immunotherapy makes anti-cancer chemotherapy more efficient
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
News • Blood-based diagnosis of glioblastoma
Sparing brain cancer patients from undergoing risky surgery
A simple blood test could help diagnose patients with glioblastoma, the deadliest form of brain cancer, sparing them from undergoing invasive and highly-risky surgery, report UK researchers.
News • Updated diagnostic criteria
Parkinson's: New three-type classification
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
News • Machine learning in sample analysis
Lab-trained pathology AI meets real world: ‘mistakes can happen’
AI models are highly capable in analysing tissue samples – as long as conditions are lab-perfect. Add a little contamination, however, and diagnostic accuracy goes out the window, a new study shows.
News • Focus on autoreactive T lymphocytes
Guillain-Barré Syndrome: researchers find cause
The underlying mechanisms of Guillain-Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.
News • Complication prevention
Placenta organoids help understand pre-eclampsia and pregnancy disorders
Using lab-grown ‘mini-placentas’, researchers from the UK and Switzerland hope to get new insights on dangerous pregnancy complications, such as pre-eclampsia.
Article • Next-generation pathology
Multiplexed staining techniques in the fight against complex diseases
Bringing digital pathology together with novel multiplexed staining techniques may answer key questions about complex diseases. Pathologist Lukas Marcelis, MD, PhD, believes such combinations of technology will have benefits for clinicians and patients and can help unravel some of the mysteries surrounding a range of conditions.
News • Finding therapy-relevant genetics
Leukaemia: AI provides support in diagnostics
Certain genetic features are crucial for treatment decisions for AML leukaemia. A team from Münster shows how an AI-based method can predict these features from images of bone marrow smears.
News • Noninvasive fetal screening
Blood test to identify genetic diseases in unborn babies
A research team from Denmark has developed an innovative screening test. With a blood sample from the expectant mother, they can scrutinize all the genes in the fetus.
News • Life sciences and the environment
New award rewards sustainability in the lab
To recognize and support pioneering efforts in life science laboratory settings, EMBO launches its Lab Sustainability Award. Applications can be submitted soon.
News • Raman spectroscopy
Novel bacteria identification methods to speed up disease diagnosis
A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
News • CTC, ctDNA and exosomes in PCa management
Prostate cancer: Blood-based liquid biopsies yield valuable information
US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.
News • Friend and foe in one
Breast cancer: The paradoxical role of white blood cells
White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.
News • Unexpected behaviour
Pathogens can force their way through the immune defense, new study shows
Breaking & entering – on a minuscule scale: US researchers have shown how some pathogens like Toxoplasma can enter cells using physical force to cause an infection.
News • Impaired immune response
Research identifies being overweight as risk factor for Covid-19 severity
Being overweight – not just being obese – can increase Covid-19 severity. the elevated BMI creates an impaired antibody response to SARS-CoV-2 infection but not to vaccination, new research finds.
News • SCN tumor development
How prostate cancer grows aggressive to evade treatment
In a new study, UCLA researchers demonstrated how small cell neuroendocrine prostate cancer tumor cells can arise from less aggressive prostate tumors.
News • Based on image-based flow cytometry
Rapid test to predict severe Covid-19 infections
Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…
News • Troponin assessment
Blood test aids emergency diagnosis of heart conditions
A high sensitivity blood test can improve diagnosis for one in five patients who have a heart muscle injury, according to new research.
News • WSI-based analysis
AI-driven classification of diffuse gliomas skips molecular testing
Research from Shenzhen proposes an integrated diagnosis model for automatic classification of adult-type diffuse gliomas directly from annotation-free standard whole-slide pathological images.