News • Tailored chatbot
Customized ChatGPT to advance digital pathology
New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.
News • Tumour infiltrating lymphocyte measurement
Breast cancer: AI tool predicts which DCIS cases become invasive
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
News • HPV oncoprotein quantification
Urine test improves cervical cancer early detection
A new test shows promise in making cervical cancer screening more accessible and less invasive by detecting oncoproteins of the human papillomavirus (HPV) in urine samples.
News • Circulating tumor extracellular vesicles
Metastatic prostate cancer: better monitoring with new liquid biopsy method
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
News • Tracking the spread and evolution of superbugs
Mapping the movement of people (and their pathogen travel companions)
Integrating bacterial genomic data with detailed human mobility data makes it possible to see how pathogens causing pneumonia and meningitis, move between regions and evolve over time.
News • "Candycrunch"
AI and mass spectrometry to find cancer clues at lightning speed
Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.
News • Infection control
C. diff: diagnostic stewardship reduces unnecessary testing
A new study describes the outcome of a new approach to testing for Clostridioides difficile (C. diff) guided by the principles of diagnostic stewardship, to help rein in the overtreatment of patients.
News • Biomarkers enhance early detection
Parkinson's: blood test predicts disease up to seven years before symptoms
A novel blood test shows promise to predict Parkinson's disease in risk patients up to seven years before the typical motor symptoms appear.
News • Combined ESR and CBC/DIFF
Horiba launches new compact hematology analyzers
Analytical and measurement technology specialist Horiba has expanded its compact hematology instrument range with the launch of new models with Erythrocyte Sedimentation Rate (ESR) on board.
News • Millifluidic nanogenerator
Blood-powered lab-on-a-chip to enhance disease monitoring
Researchers are proposing a new device that uses blood to generate electricity and measure its conductivity, opening doors to medical care in any location.
Article • Challenges and opportunities
Molecular pathology in Europe: in search of standardization
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
News • Foetal development research
Tracing back the origins of AML childhood leukaemia
Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.
News • Infectious disease diagnostics
POCT for remote areas: Portable pathology passes the test
When point-of-care testing (POCT) models for diagnosing infectious disease are effective, the quality of pathology results can be equivalent to laboratory tests, new research shows.
Sponsored • Laser cassette printer
Leaping forward with laboratory workflow automation
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News • Neuropathology
Technology offers new insights into pediatric brain tumors
A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.
News • Integration of microanalysis chips
Establishing microfluidic control technology for blood testing devices
A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.
Article • Pros and cons of diagnostic techniques
Liquid biopsy vs. tissue biopsy: Getting the best of both worlds
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
News • Heteroresistance
Researchers discover new mechanisms behind antibiotic resistance
A new study explores the phenomenon of heteroresistance in bacteria, which is a key driver of antibiotic resistance. Two new discoveries could impact the development of future AMR strategies.
News • Axon vulnerability to damage
Male and female brains are different – and so are the effects of concussions
Structural differences in male and female brains might explain why women are more prone to concussions and experience longer recovery from the injury than men, according to a new preclinical study.
News • Three-dimensional tissue processing
Pathology performs leap into 3D with AI
Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.
News • Vaccines for future pathogens
“We don’t have to wait for new coronaviruses to emerge”
A new approach to vaccine development could produce vaccines before the disease-causing pathogen – such as a new variant of the coronavirus Sars-CoV-2 – even emerges.
News • Research on autoantibody patterns
The unique and complex origins of rheumatoid arthritis
New research challenges assumptions about the origin of rheumatoid arthritis, which are probably too simple. The findings may point towards improved diagnostics of this painful autoimmune disease.
News • Leukemia MRD after chemo
AML: Residual cancer testing as an important safeguard
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
News • Transfusion medicine
One step closer to universal donor blood
Donor blood is a scarce and valuable resource. Researchers aim to mitigrate this by using enzymes to remove specific sugars that make up the A and B antigens in the human ABO blood groups.
News • Gene-snipping bacterial defenses
CRISPR: a promising tool to fight antibiotic resistance, but...
Could the 'gene scissors' CRISPR be used to make resistant bacteria susceptible to first-line antibiotics again? According to new reseach, yes – but the experts also point out serious caveats.
