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A “diagnostic wand” to detect oral cancer
Liverpool physicists have developed a “diagnostic infrared wand” to more accurately predict the prognosis of oral cancer lesions than current H&E staining techniques.

Liverpool physicists have developed a “diagnostic infrared wand” to more accurately predict the prognosis of oral cancer lesions than current H&E staining techniques.

By analysing the largest collection of whole-genome data from osteosarcoma patients, researchers identified a driving mechanism behind the aggressive development of these bone cancer tumours.

A new personalised oncology platform has been tested to detect circulating tumour DNA (ctDNA) in patients with lung adenocarcinoma before surgery, to predict their risk of cancer relapse.

Researchers uncovered a surprising link between Alzheimer’s disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease.

Complex diseases could require complex biomarkers for accurate diagnosis in the years ahead, according to a leading pathologist. In a keynote address to the 36th European Congress of Pathology in Florence, Italy, Professor Manuel Salto-Tellez highlighted this as one of the major future challenges for the discipline. However, he also believes pathologists will sit at the core of modern medicine.

Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.

Analyses of self-tests for human papillomavirus (HPV) can be used to divide HPV-positive women into three risk groups, according to a new study. This could enhance cervical cancer screening.

Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.

Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.

Sakura Finetek Europe and MEDIPATH, a group of independent French pathologists, announced their collaboration to enhance cancer diagnostics and thus contribute to improved patient therapeutic management. This decision is part of an ongoing commitment to improving the quality of care provided to patients and in response to the significant increase in cancer cases over the last years.

New study results could help detect whether a newborn baby with fever has sepsis or another serious bacterial infection, without the need for invasive testing.

A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.

A new study shows how inherent variations in a cancer cell and its interactions with its surroundings mould its migration. The findings provide valuable insights into the processes behind metastasis.

New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.

Two studies indicate warning signs about spread of bacteria resistant to the same group of antibiotics (carbapenems) in both healthcare and community settings across Europe.

In the laboratory, researchers increased the bactericidal effect of antibiotics 64-fold with the use of a new hydrogel. The material made the antibiotics effective even against resistant bacteria.

New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.

Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.

Skills shortages and digitalization, trends in cardiology and oncology, future prospects in laboratory medicine, and healthy aging – these pressing topics are at the forefront of discussions at this year’s Medica Labmed Forum.

Wastewater treatment fails to kill several human pathogens, such as Listeria or E. coli, when they hide out on microplastics in the water, according to a new study.

Researchers from China have developed ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer.

Artificial Intelligence (AI) remains a divisive topic within the discipline of pathology with a range of opinions over its current value and applicability in clinical settings. While most experts agree that the technology will not replace pathologists, it might still spell bad news for those who do not embrace AI in their daily practice. On the other hand, reservations persist about whether…

Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…

Women with type 1 or type 2 diabetes often have difficulty getting pregnant, due to complications from the disease, being obese or seriously underweight, or having conditions like polycystic ovary syndrome. Once pregnant, they face challenges of having a safe pregnancy and delivering a healthy baby. Recent advances in diabetes technology, including continuous glucose monitoring (CGM) and most…

New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.