Taking clear pictures of megaenzymes isn’t easy. But it’s definitely worth it. These proteins play an active role in creating many common antibiotics. They are in constant motion, with sections that flip around acrobatically to carry out necessary tasks. Now, for the first time, McGill researchers have been able to take a series of 3D images of a large section from one of these…
A research team from the University of Liverpool has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.
There’s apparently safety in numbers, even for cancer cells. New research in mice suggests that cancer cells rarely form metastatic tumors on their own, preferring to travel in groups since collaboration seems to increase their collective chances of survival, according to researchers at Johns Hopkins.
Surgeons removing a malignant brain tumor don't want to leave cancerous material behind. But they're also trying to protect healthy brain matter and minimize neurological harm.
Scientists of the Göttingen Cluster of Excellence CNMPB and the EMBL describe efficient fluorescence tag for super-resolution microscopy.
Automated latex enhanced immunoturbidimetric H-FABP assay helps emergency departments to detect MI within 30 minutes of chest pain onset, and improve the diagnostic efficiency of Troponin.
For the first time, and using physical methods, scientists have demonstrated how red blood cells move. They recognized that fast molecules in the vicinity make the cell membrane in the blood cells wriggle – but that the cells themselves also become active when they have enough reaction time.
Researchers at Duke Health are fine-tuning a test that can determine whether a respiratory illness is caused by infection from a virus or bacteria so that antibiotics can be more precisely prescribed.
Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.
When cells die, they don't vanish without a trace. Instead, they leave behind their fingerprints in the form of cell-free DNA. In people, these tiny fragments of DNA can be found in the bloodstream.
EKF Diagnostics, the global in vitro diagnostics company, announces the publication of its new guide, "Anemia and hemoglobin testing". Available to download for free, the in-depth hematology guide provides a review of the symptoms and causes of anemia, through to methods for testing hemoglobin and hematocrit, as well as factors that may influence these measurements.
Healthcare, the world’s largest industry, is more than three times the size and value of the financial services sector, and is transforming faster than ever before, driving humanity to rethink the way we approach our health.
Post mortems are now rarely carried out within UK hospitals – according to a study that examined all acute NHS Trusts within England, NHS Boards in Scotland and Wales and Social Care Trusts in Northern Ireland, and found that the process has disappeared completely in around a quarter (23%) of NHS trusts. In 2013, the average autopsy rate (percentage of adult in-patient deaths that undergo…
In addition to physical examinations, medical history laboratory test results are critical in almost all medical decisions made in the hospital. The demand for adequate, fast measurements has increased exponentially over at least the last 50 years and may have increased 100-fold, or more, since the 1950s. This could not have been achieved without the introduction of partial or full automation, of…
Royal Philips and Banyan Biomarkers, Inc. today announced that they have entered into a multi-year joint development agreement to develop and commercialize a new handheld blood test to detect and evaluate mild traumatic brain injury (TBI) - also known as concussion - at the point of care. The new handheld test will be based on Philips’ Minicare I-20 system. The financial details of the…
Australian scientists have for the first time revealed how malaria parasites cause an inflammatory reaction that sabotages our body's ability to protect itself against the disease. The discovery opens up the possibility of improving new or existing malaria vaccines by boosting key immune cells needed for long-lasting immunity. This could even include vaccines that have previously been ineffective…
Proteins are like a body’s in-house Lego set. These large, complex molecules are made up of building blocks called amino acids. Most of the time, proteins fold correctly, but sometimes they can misfold. This misfolding causes the proteins to get sticky, and that can promote clumping, or aggregation, which is the hallmark of several neurodegenerative diseases such as ALS, Alzheimer’s and…
Antibodies combat viruses and bacteria. They also attach themselves to cancer cells – in a typical, characteristic way. Fraunhofer scientists are using this property to detect cancer cells in tissue samples. Such rapid tests can already be applied by surgeons during operations – within a few minutes and without expensive equipment.
Scientists have shown for the first time that an enzyme crucial to keeping our immune system healthy “surfs” along the strands of DNA inside our cells. The researchers used extremely powerful microscopy to watch how the enzyme AID (activation-induced deoxycytidine deaminase) moves around and interacts with other molecules.
The Smart One achieved the Product of Outstanding Interest (POINT) award for diagnostic devices at the European Respiratory Society (ERS) International congress in Amsterdam, The Netherlands.
The detection of light by pigments in the retina, called rhodopsin or visual purple, leads to our sense of vision. New experiments by scientists from the Max Planck Institute for the Structure and Dynamics of Matter and the University of Toronto have revealed that the primary photochemical event of this process operates at the fundamental molecular speed limit.
Collaborating with colleagues locally and globally using telepathology can be successful for facilities both financially and clinically, says Dr. Liron Pantanowitz, director of pathology informatics at University of Pittsburgh Medical Center (UPMC). Pantanowitz, who also serves as a consultant to Onyx, a company that provides digital pathology technology and is joint venture between GE Healthcare…
The field is so new that the annual Digital Pathology Congress (3-4 December in London) was held for only the second time. Yet, Philips Healthcare could announce a world-first – in partnership with the Netherlands-based LabPON, the company has created the first clinical pathology laboratory to be completely converted to digital diagnosis.
Bladder cancer is associated with high recurrence rates, necessitating prolonged surveillance and repeated treatments. As a result, it is one of the most challenging and costly of all solid tumours to manage. Although most patients present at an early stage with non-muscle-invasive bladder cancer (NMIBC), between 13% and 61% will experience recurrence within 1 year of initial transurethral…
Patients with multiple sclerosis often receive a "hit and miss" treatment when the disease breaks out. A blood analysis is now for the first time able to reveal which of the two most important first-line drugs is better suited for which patients.
