Neuroscience
An unexpected role for the brain's immune cells
Researchers have discovered that microglia cells constantly survey the brain to prevent spontaneous seizures.
Search for: "autism" - 39 articles found
Memory formation
Unlocking the mysteries of the brain
A Canadian research team highlights the mechanisms underlying memory and learning capacity – specifically, how our brains process, store and integrate information. How does our brain store information? Seeking an answer, researchers at CHU Sainte-Justine Hospital and Université de Montréal have made a major discovery in understanding the mechanisms underlying learning and memory formation.…
Neurology research
Calcium channel subunits play a major role in autistic disorders
The ability of the human brain to process and store information is determined to a large extent by the connectivity between nerve cells. Chemical synapses are very important in this context as they constitute the interface for the transmission of information between individual nerve cells. Abnormalities in the formation of synapses cause many neurological disorders such as autism. Neurobiologists…
Intestinal bacteria reprogram DNA activity
The uncanny influence of our gut flora
Scientists from the German Cancer Research Center (DKFZ) and the Hebrew University in Jerusalem demonstrated in mice that intestinal bacteria reprogram DNA activity in cells of the gut mucosa and thus have a considerable impact on the development of the healthy gut.
Measles
Vaccine hesitancy threatens global health
Globally, a trend of falling public trust in vaccines is alarming health officials and the World Health Organisation (WHO) lists vaccine hesitancy as one of the top 10 threats to global health. The UK’s Wellcome Trust 2018 Global Monitor – a survey of more than 140,000 people in over 140 countries – highlighted regions where confidence in vaccinations is lowest.
Mental health
Does autism increase risk of suicidal behaviour?
The risk of suicide attempts and suicides among individuals with autism spectrum disorders is significantly higher than among the population in general. An especially high risk of suicidal behaviour is noted among women who in addition to autism also have ADHD. These are the findings of a population-based study from Karolinska Institutet in Sweden published in the journal Psychological Medicine.…
Psychiatry
Leonardo da Vinci: pure genius or ADHD?
Professor Marco Catani suggests the best explanation for Leonardo da Vinci's inability to finish his works is that the great artist may have had Attention Deficit and Hyperactivity Disorder. Leonardo da Vinci produced some of the world’s most iconic art, but historical accounts of his work practices and behaviour show that he struggled to complete projects. Drawing on these accounts, Professor…
Antisocial behaviour
How the brain of children with conduct disorder is different
Behavioural problems in young people with severe antisocial behaviour – known as conduct disorder – could be caused by differences in the brain’s wiring that link the brain’s emotional centres together, according to new research led by the University of Birmingham. Conduct disorder affects around 1 in 20 children and teenagers and is one of the most common reasons for referral to child…
Neurodegeneration
Study sheds new light on microglia
Inside the body, disease and injury can leave behind quite the mess — a scattering of cellular debris, like bits of broken glass, rubber and steel left behind in a car accident. Inside the central nervous system (CNS), a region that includes the brain and spinal cord, it is the job of certain cells, called microglia, to clean up that cellular debris. Microglia have counterparts called…
At age 2
AI and MRIs at birth can predict cognitive development
Researchers at the University of North Carolina School of Medicine used MRI brain scans and machine learning techniques at birth to predict cognitive development at age 2 years with 95 percent accuracy. “This prediction could help identify children at risk for poor cognitive development shortly after birth with high accuracy,” said senior author John H. Gilmore, MD, Thad and Alice Eure…
Some problems remain
Some children can 'recover' from autism
Research in the past several years has shown that children can outgrow a diagnosis of autism spectrum disorder (ASD), once considered a lifelong condition. In a new study, researchers at Albert Einstein College of Medicine and Montefiore Health System have found that the vast majority of such children still have difficulties that require therapeutic and educational support.
Psychopathology
Is terrorism based on mental illness?
Were Anders Breivik’s actions the work of a madman? Is Theo van Gogh’s killer Mohammed Bouyeri a psychopath? Much is still unclear about the role of psychological disorders (psychopathology) in terrorism. While some research supports the idea that terrorists are mentally ill, other studies contradict this view. In a study commissioned by the Research and Documentation Centre/Dutch Ministry of…
Chronic peripheral inflammation and schizophrenia
The network approach to mental illness research
As European health services are pressured to provide the best possible care for best possible value, some medical fields are now very much the poor relation; this is particularly true for mental health. Mental illnesses represent a great health burden and cause huge financial and societal pressure in terms of direct and indirect costs from repeated hospitalisation and treatment failures, while…
Solving a medical mystery
Cause of rare type of dwarfism discovered
Scientists have uncovered the cause of Saul-Wilson syndrome: A single, spontaneous gene change alters protein packaging in the cell’s Golgi complex, causing the disease.
IT solutions
Big data: Utilising potential where it presents itself
Useful IT tools are abundant in today’s laboratories – ranging from software to evaluate analyses to specialist software for quality control, and middleware linking different devices. However, all these tools generate data, the adequate utilisation of which is not an easy task, said Udo Margraff, CEO of Laboratoires Réunis in Luxembourg, during our European Hospital interview. Among other…
Study results
Dieting does not help autistic kids with GI trouble
Many children with autism spectrum disorder experience significant gastrointestinal issues, but the cause of these symptoms is unknown. Professionals in the medical community have suggested a potential link between diet and gastrointestinal issues related to autism. Now, researchers from the University of Missouri School of Medicine have found that diet is not a contributing factor in these…
Behavioral study
New understanding for autism through eye tracking
New research has uncovered compelling evidence that genetics plays a major role in how children look at the world and whether they have a preference for gazing at people’s eyes and faces or at objects. The discovery by researchers at Washington University School of Medicine in St. Louis and Emory University School of Medicine in Atlanta adds new detail to understanding the causes of autism…
Osteoporosis
Making bones stronger through math
Mathematical model shows injections of peptide could raise density of bones badly degraded by osteoporosis back to healthy levels.
Autism
Big Data techniques find biomarkers for Autism Spectrum Disorder (ASD)
An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study. The algorithm, developed by researchers at Rensselaer Polytechnic Institute, is the first physiological test for autism and opens the door to earlier diagnosis and potential future development of therapeutics.
Pediatrics
Technology reveals fetal brain activity
NIBIB-funded researchers at the University of Washington have pioneered an approach to image functional activity in the brains of individual fetuses, allowing a better look at how functional networks within the brain develop. The work addresses a common problem of functional MRI; if the subject moves during the scanning, the images get distorted.
Freaky new role
Immune system controls social interaction
In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects – and even controls – creatures’ social behavior, such as their desire to interact with others. So could immune system problems contribute to an inability to have normal social interactions? The…
Map
How the brain is organized
The age of exploration has long passed, but there is at least one area still largely uncharted: the human brain. Now, a detailed new map by researchers at Washington University School of Medicine in St. Louis lays out the landscape of the cerebral cortex – the outermost layer of the brain and the dominant structure involved in sensory perception and attention, as well as distinctly human…
Telemedicine
Benefits to using telehealth with ASD families
Telemedicine - connecting health care providers and patients via computer or smart phone for diagnosis and treatment - has been making it easier, and more cost-effective, to "see" the doctor. Using a camera-enabled computer or smart phone, patients with common health concerns can get some diagnoses without leaving their homes. Emergency room doctors and nurses are able to communicate…
Mathematical Model
Explain with math the mutation rates in human genome
It turns out that the type, how frequent, and where new mutations occur in the human genome depends on which DNA building blocks are nearby, found researchers from the Perelman School of Medicine at the University of Pennsylvania.
Telemedicine effective for patient
More than 50 million Americans live in rural areas, and many have limited access to health care. For someone living far from an urban area, local specialty care for complex health issues is difficult, if not impossible, to obtain. For years, telemedicine programs across the country have connected rural patients to specialists in urban settings. Now, a study by University of Missouri School of…
Silicon
Research center combine electronics and photonics in neural probes
At the IEEE International Electron Devices Meeting 2015, world-leading nanoelectronics research center imec, KU Leuven, and Neuro-Electronics Research Flanders (NERF, set up by VIB/KU Leuven and imec) presented a set of silicon neural probes that combine 12 monolithically integrated optrodes using a CMOS compatible process.
Social interactions
‘Love hormone’ helps produce ‘bliss molecules’
The hormone oxytocin, which has been associated with interpersonal bonding, may enhance the pleasure of social interactions by stimulating production of marijuana-like neurotransmitters in the brain, according to a University of California, Irvine study.
Sex-linked disorders
X-Citing X Chromosome
A team of scientists from the University of Michigan Medical School shows that the genetic material in female (but not male) cells makes tiny amounts of a special genetic material called RNA to make one of the two X chromosomes silent. They call this RNA XistAR.
Neurology
Improved brain implants
By implanting electrodes in the brain tissue one can stimulate or capture signals from different areas of the brain. These types of brain implants, or neuro-prostheses as they are sometimes called, are used to treat Parkinson's disease and other neurological diseases.
Discovery
Researchers reveal cellular clockwork underlying inflammation
Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation -- a discovery that could have important implications for the treatment of allergies, heart disease, and certain forms of cancer.
Neurology
Receptors in brain linked to schizophrenia, autism
The loss of a critical receptor in a special class of inhibitory neurons in the brain may be responsible for neurodevelopmental disorders including autism and schizophrenia, according to new research by Salk scientists.
Genetic Disorder
How to predict development of autism or psychosis
Doctors and researchers have long known that children who are missing about 60 genes on a certain chromosome are at a significantly elevated risk for developing either a disorder on the autism spectrum or psychosis — that is, any mental disorder characterized by delusions and hallucinations, including schizophrenia. But there has been no way to predict which child with the abnormality might be…
Neurology
Balanced behavior with IRBIT
Hyperactivity and social abnormalities are defining characteristics of ADHD and autism, two developmental disorders that parents and scientists around the world are struggling to understand. At the RIKEN Brain Science Institute in Japan, researchers have identified the protein IRBIT as a key player in preventing these behaviors from developing.
The hubs and spokes of brain traffic
New insights into the ways the human brain functions – that is the promise of mapping the entire web of connections in the brain, the so-called connectome. New developments in connectome imaging are one of the major topics at this year’s European Congress of Radiology (ECR).
Searching Brain Pathways for Clues on Autism
Timothy Roberts, PhD, works in the middle of an epidemic. In the 20 years the researcher has studied autism, the diagnosis rate among children in the United States has risen from one in 1,000 to one in 88. No one is sure of the cause, how to prevent it, or how to treat it.
Schizophrenia gene discovered
Working independently from different perspectives, geneticists from Finland and biochemists from Würzburg have researched the molecular mechanisms of schizophrenia and cognitive impairment.
Measles and whooping cough cases are on the rise
When country doctor Edward Jenner inoculated 8-year-old James Phipps with pus from a cowpox lesion on a milkmaid’s hand, little did he know that he had started a long lasting revolution in preventive medicine.
Fear of relationships - it's in the genes
There can be many reasons why a person might have relationship problems, but now Swedish scientists at Medical University Karolinska Institutet found a specific gene variant that is associated with how men bond to their partners. The insights can lead to a better understanding of such problems as autism and social phobia.
Expanding medical horizons
This was the motto of the ECR 2007 in Vienna, where a group of high-ranking experts discussed diseases of the 21st century; research competition between the US and Europe; the conditions needed to progress leading medical R&D - moderated by Congress President Professor Christian J Herold.