Clinical trials are a critical tool for getting new treatments to people who need them, but research shows that difficulty finding the right volunteer subjects can undermine the effectiveness of these studies. Researchers at Cincinnati Children’s Hospital Medical Center designed and tested a new computerized solution that used artificial intelligence (AI) to effectively identify eligible…
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body’s metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence. A research group led by Matteo Serino, Inserm researcher at the Digestive Health Research…
Our eyes – considered by many to be the windows to the soul – need constant care, and as we age, they sometimes also need significant repair. The panes of these windows – the corneas – are transparent tissues that have been the focus of some of the oldest and most common transplantation surgeries. Now thanks to researchers in Kyoto, some such transplants may become even safer. The team,…
A team led by scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) developed an algorithm that a computer could use to conduct a similar type of search in microbial and metagenomic databases. In this case, the machine “learned” to identify a certain type of bacterial viruses or phages called inoviruses, which are filamentous viruses with small, single-stranded DNA…
Think twice before adding that extra kick of chili sauce or chopped jalapeno to your meal. New research involving the University of South Australia shows a spicy diet could be linked to dementia. A 15-year study of 4582 Chinese adults aged over 55 found evidence of faster cognitive decline in those who consistently ate more than 50 grams of chili a day. Memory decline was even more significant if…
More cancer, more cardiovascular disease: The relaxation of UK industry regulation of salt content in food was – to put it lightly – a very bad idea, say researchers from Imperial College London and the University of Liverpool. They have linked the change in regulation with 9,900 additional cases of cardiovascular disease (CVD), and 1,500 cases of stomach cancer. The researchers analysed the…
Researchers in the Medical Sciences Division of Oxford University have established a key cause of micro blood vessels constricting during surgery to reopen a blocked artery, and identified a potential therapeutic target to block the mechanism behind it. During the emergency procedure used to reopen the blocked artery causing a heart attack, smaller "micro" blood vessels can remain…
Healthcare in low- and middle-income countries is poorly prepared for the increasing number of people with high blood pressure, with more than two-thirds of people affected going without treatment – a new study reveals. Researchers studied health data for one million people in the Global South, discovering that less than half of those affected are diagnosed with high blood pressure or…
Nations with strong women’s rights are more likely to have better health and faster growth than those who don’t promote and protect these values, finds research published in the online journal BMJ Open. This trend is evident in even in resource-poor countries, say the researchers. While many parts of the world have made good economic progress, women’s rights have often been overlooked, say…
Researchers at Lund University in Sweden have investigated the link between osteoarthritis and mortality in an epidemiological study. It was shown that the risk of dying from cardiovascular disease was higher for people with osteoarthritis than for the rest of the population. Using population registers, the researchers studied approximately 469 000 people living in Skåne, Sweden, who in 2003…
Scientists have developed minute flexible robots that could help revolutionise drug delivery in the future. These ‘microrobots’ are so small that they could be ingested, or inserted into human veins to deliver drug therapies directly to diseased body areas.
A team of researchers from the SingHealth Duke-NUS Academic Medicine Centre’s Viral Research and Experimental Medicine Centre (ViREMiCS) found that immune cells undergoing stress and an altered metabolism are the reasons why some individuals become sick from viral infections while others do not, when exposed to the same virus. The findings, published in medical journal Nature Medicine, have…
Norfolk and Norwich University Hospital (NNUH) Consultant Radiologist Tom Turmezei has been awarded the prestigious Royal College of Radiologists’ Roentgen Professorship for 2020, a role created to encourage trainee radiologists across the UK to participate in research. “Research is absolutely key to making discoveries that will improve the diagnosis and treatment of patients in the…
The practice of taking small, regular doses of psychedelic drugs to enhance mood, creativity, or productivity lacks robust scientific evidence, say scientists. The process, called microdosing, has been lauded by some, with high profile proponents in Silicon Valley. But to date, scientific evidence to support or even fully explore claims of the benefits and safety, has been lacking. Now, an…
Siemens Healthineers, University of Missouri System (UM System) and University of Missouri Health Care (MU Health Care) launch "Alliance for Precision Health.” The ten-year collaboration will bring the partners’ expertise together to improve health care in Missouri State, promote education and launch research initiatives. Among other things, the clinic receives the only 7 Tesla MRI…
For patients with Type 1 diabetes who don’t respond well to insulin or have other serious medical complications caused by their disease, pancreas transplantation offers hope for a cure. But obese candidates who need a pancreas transplant often are denied the procedure because of poor outcomes, including high rates of incision infections, which are linked to an increased risk for failure and…
Researchers at the University of Helsinki have discovered how regenerative capacity of intestinal epithelium declines when we age. Targeting of an enzyme that inhibits stem cell maintaining signaling rejuvenates the regenerative potential of an aged intestine. This finding may open ways to alleviate age-related gastrointestinal problems, reduce side-effects of cancer treatments, and reduce…
In the most comprehensive study of its kind, researchers from the Department of Nutritional Sciences at the University of Surrey investigated if protein intake can impact bone health of adults and children. Examining 127 previous studies published over a 40 year period, which scrutinised the link between protein and bone density, bone mineral content and relative risk of osteoporotic fractures,…
A strain of the common cold virus has been found to potentially target, infect and destroy cancer cells in patients with bladder cancer. No trace of the cancer was found in one patient following treatment with the virus. The researchers published their findings in the medical journal Clinical Cancer Research. Researchers from the University of Surrey and Royal Surrey County Hospital investigated…
Research led by the University of Birmingham has found important new ways that the BRCA1 gene functions which could help develop our understanding of the development of ovarian and breast cancers. The research, published in Nature, was led by experts at the University of Birmingham’s Birmingham Centre for Genome Biology and Institute of Cancer and Genomic Sciences and is part of a five-year…
Scientists have identified mechanisms in the human brain that could help explain the phenomenon of the 'Uncanny Valley' - the unsettling feeling we get from robots and virtual agents that are too human-like. They have also shown that some people respond more adversely to human-like agents than others.
The risk of suicide attempts and suicides among individuals with autism spectrum disorders is significantly higher than among the population in general. An especially high risk of suicidal behaviour is noted among women who in addition to autism also have ADHD. These are the findings of a population-based study from Karolinska Institutet in Sweden published in the journal Psychological Medicine.…
Engineers at the University of Edinburgh have devised a fabric dressing whose thickness and elasticity can be custom-matched to specific areas of the body. The material is able to be absorbed by the skin’s own tissue as it heals. Two synthetic materials are blended to produce nanometre-sized fibres – thousands of times thinner than a hair – which can be fabricated in minutes. Edinburgh…
Vaccinating schoolboys against the potentially deadly human papillomavirus (HPV) could dramatically reduce head and neck cancers in men, according to research involving the University of Strathclyde. The two-year project studied 235 patients in Scotland with head and neck cancer and found that 78% of people with head and neck cancers were men, while HPV was present in 60% of the cancers. This…
For over 20 years, a team of researchers at Lund University has worked on developing a drug against preeclampsia – a serious disorder which annually affects around 9 million pregnant women worldwide and is one of the main causes of death in both mothers and unborn babies. Now the researchers have published a study in the journal Scientific Reports that opens up opportunities for further…
