News • Immunology
Researchers discover new type of anticancer T-cell
A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.
Cells
News • Inclusion of all cell lineages
Advanced pancreas organoid for better insights
A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.
News • Dermatology
Exploring fibroblast subtypes and skin cancer aggressiveness
New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.
News • New insights on aneuploid epithelial cells
Breast cancer-like cells also found in healthy women
A certain type of cells, called aneuploid epithelial cells, are usually associated with breast cancer. However, new research reveals that they can also be found in healthy women.
News • Exploring potential and limitations
Bedside bioprinting: the future of regenerative medicine?
To take cell therapy in regenerative medicine to a new level, experts consider 3D bioprinting a key technology. However, there are still quality issues that need to be overcome to achieve this.
News • Microgravity-induced changes
How cancer cell cultures in space can help defeat cancer on Earth
New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.
News • Research on "double strike" mechanism
Induction of defective cell division could improve blood cancer therapy
Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.
News • Hibernation
Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold
A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.
News • DNA damage response
New insights into the DNA damage response
The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.
News • Single-cell metabolic profiling
Mass-spec and IMC give deep insights into tumors
By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.
News • Reducing chemotherapy side effects
Trapping cancer cells in molecular 'cages'
Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.
News • High-resolution cell scans
AI spots cancer and viral infections at nanoscale precision
Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.
News • Synthetic nanofibers
Repairing cartilage damage with ‘dancing’ molecules
US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.
News • Adaptive mutability
How bowel cancer flips the switch to avoid immune detection
Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.
News • Vital mechanism discovered
Promising approach to prevent breast cancer recurrence
Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.
News • Research on immune system responses
Allergy or infection? Scientists discover distinguishing features
Scientists discover how the production of antibodies is regulated in allergy and infections. This opens the door to new therapies, without affecting the beneficial response of the immune system.
News • Research on DNA danage
Surprise finding on cancer cell death to impact therapies
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
News • 6.5 million European funding
Fighting cancer with artificial cells and tissue
Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.
News • Leukemia MRD after chemo
AML: Residual cancer testing as an important safeguard
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
News • Opportunity for new treatment approaches
Atherosclerosis and cancer share surprising similarities, study finds
In cancer, cell deterioration can drive progression. A similar process happens in artherosclerosis, new research reveals. This finding could lead to new ways of combatting disease-causing plaque.
News • Generation of alveolar epithelial type I cells
Study furthers understanding of lung regeneration
Researchers present a new method for generating human alveolar epithelial type I cells. This could ultimately progress therapies for people living with pulmonary diseases.
News • Novel probe assesses cell stiffness
A 3D endo-microscope for early cancer diagnosis
Stiffness in tissues can be a valuable indicator of cancer formation. Now, researchers have developed a microscopic probe to perform histology at the single cell level inside the human body.
News • Bioinformatics
New tool identifies chromosomal instability in cancer cells
A new detection tool is designed to contribute to improving tumour research and classification by identification and quantification of chromosomal instability in the nuclei of cancer cells.
News • Characterization of cancer relevant genes
Breast cancer: Researchers take a deep dive into cell lines
Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.
News • Mitosis profiling
AI tool helps grade cancer based on cell divisions
Ahead of World Cancer Day on 4 February, scientists are revealing a cutting-edge artificial intelligence (AI) tool designed to help grade cancer, by analysing cell division.
