News • Astrocyte research
New insight into how cancer metastasizes to the brain
A new US-led study shows that astrocyte brain cells play an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.
Immune system
News • Mysterious mechanism solved
Researchers discover how bowel cancer 'blinds' the immune system
A mystery which has stumped bowel cancer researchers for decades, has been solved by scientists at the Cancer Research UK Beatson Institute and University of Glasgow.
Article • Cancer patients at risk
Blood test detects risk of neurotoxicity from CAR T-cell therapy
Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…
News • Counteracting neuroinflammation
Multiple sclerosis: Why women get better when pregnant
Women suffering from multiple sclerosis temporarily get much better when pregnant. Researchers have now identified the beneficial changes naturally occurring during pregnancy.
News • Potential blood cancer treatment
CAR T cell therapy: study shows remote destruction of tumor cells
French scientists discovered that CD4 T cells generated during immunotherapy are capable of remotely neutralizing tumor cells by producing interferon gamma (IFN-γ).
News • Role of EBV in MS progression
New study explains how Epstein-Barr virus causes multiple sclerosis
Researchers at Karolinska Institutet have found further evidence for how the Epstein-Barr virus (EBV) can trigger multiple sclerosis (MS) or drive disease progression.
News • Oncology & Immunology
Researchers find new IgE antibody targeting skin cancer
A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.
News • Promising biomarker found
Who will develop long Covid? It's in the blood
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.
News • Understanding the role of sex hormones
Multiple sclerosis: Why are women affected more often?
Multiple sclerosis affects three women for every one man. French scientists are studying the role of the sex hormones in order to better understand this discrepancy.
News • Immunotherapy effectiveness
Sex differences in pancreatic cancer: researchers reveal possible explanation
For pancreatic cancer, the effect of immunotherapy is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this sex difference.
News • Preventing EBV reactivation
Liver transplantation: Finding the "sweet spot" of immuno-suppression
Dutch physicians have developed a system to determine the right dose of immunosuppressive drugs for patients to receive a donor liver - to prevent the activation of the Epstein-Barr virus.
News • Specialized immune cells
γδ T cells carry potential for new cancer immunotherapies
Dutch scientists have discovered how specialized immune cells can detect and remove cancers that are ‘invisible’ to the conventional defense mechanisms of the immune system.
News • Anosmia
Loss of smell after Covid-19: Researchers find key reason
After an infection with SARS-CoV-2, some people fail to recover their sense of smell. US researchers took a closer look at the olfactory nerve cells to find the reason for Covid-19-induced anosmia.
News • First on site, but short-lived
New insights into immune defence may explain Covid-19 reinfections
A new study has found that antibodies produced in the nose decline nine months after Covid-19 infection, while antibodies found in the blood last at least a year.
News • T cell visualization
Whole body scan shows complexity of immunotherapy response
Dutch scientists have performed whole-body PET scans using a radioactively labeled antibody tracer against immune cells, to predict the effect of treatment with immune checkpoint inhibitors.
News • Environmental medicine
Study shows how air pollution eats away at the immune system
The diminished power of the immune system in older adults is usually blamed on the aging process. But a new study shows that decades of particulate air pollution also take a toll.
News • After blood stem cell transplantation
How the immune system "reboots" in MS patients
Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study examined how the treatment curbs the disease and how the immune system regenerates afterwards.
News • Immune systems timulation
Using senescent cells as anti-cancer vaccines
Researchers from Barcelona report that vaccination with senescent cells shows promise in experimental models of melanoma and pancreatic cancer.
News • Answer to SARS-CoV-2 mutations
One step closer to 'variant-proof' Covid-19 vaccine
A vaccine design approach that could protect against new variants of SARS-CoV-2 but also potentially protects against other coronaviruses is one step closer to reality as a result of new research.
News • SARS-Cov-2 case study
Does time of day matter for Covid-19 vaccination? Probably not, study finds
A study in Japan finds antibody response to the Moderna Covid-19 mRNA vaccine does not vary depending on the time of day when the dose was received.
News • Neuroinflammation research
Exploring the long-term consequences of infections
Researchers mapped in detail how the immune system acts against pathogens invading the brain. This sheds new light on host-pathogen interactions and the long-term consequences of brain infections.
News • Disrupted neurogenesis
Covid-19 delirium: new study reveals possible brain mechanisms
Researchers have shown that when brain cells are directly exposed to blood taken from Covid-19 patients with delirium, there is an increase in cell death and a decrease in the generation of new brain cells.
News • Research presented at ESC 2022
Autoimmune disorders increase risk of cardiovascular disease
A large epidemiological study shows that patients with an autoimmune disorder have a substantially higher risk of developing cardiovascular disease than individuals without autoimmune disease.
News • Underrated helper
T-cells: key for a new type of Covid-19 vaccine?
Researchers propose a new Covid-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies - a promising alternative for people with a weakened immune system.
News • Identification of treatment barriers
Immunotherapy: The right environment for fighting cancer
Cancer immunotherapy is a successful treatment form in oncology, but it doesn't work for every patient. One problem may be the lack of a specific type of immune cell in the tumor, researchers found.
