Cancer

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News • DNA

DNA labels predict mortality

Methyl labels in the DNA regulate the activity of our genes and, thus, have a great influence on health and disease. Scientists from the German Cancer Research Center and from the Saarland cancer registry have now revealed that an altered methylation status at only ten specific sites in the genome can indicate that mortality is increased by up to seven times. Smoking has a particularly…

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News • Cancer Care

Biosimilars Create New Opportunities

Biosimilars create opportunities for sustainable cancer care, says the European Society for Medical Oncology (ESMO) in a position paper published in ESMO Open.1 The document outlines approval standards for biosimilars, how to safely introduce them into the clinic, and the potential benefits for patients and healthcare systems.

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Article • Tomasz Grodzki

Polish Senator and pioneering lung cancer surgeon

First thing on a recent Monday morning, Professor Tomasz Grodzki could be found performing a lung resection in an operating theatre at the Regional Hospital for Lung Diseases in Szczecin-Zdunowo. Just two days earlier he was in a meeting with Senator John McCain, in Washington D.C.

News • iCAGES

New precision medicine tool helps optimize cancer treatment

Columbia University Medical Center (CUMC) researchers have created a computational tool that can rapidly predict which genes are implicated in an individual’s cancer and recommend treatments. It is among the most comprehensive tools of its kind, and the first that incorporates a user-friendly web interface that requires little knowledge of bioinformatics.

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Article • Big Data

‘Dr Computer’ aids intelligent lung cancer diagnoses

In imaging diagnostics computers are taking over – well, not quite, but they might soon play an important role, according to Professor Hans-Ulrich Kauczor, Medical Director of the Clinic of Diagnostic and Interventional Radiology at University Hospital Heidelberg. Meeting with European Hospital, he discussed an EU-funded project to assess malignancy in pulmonary nodules and its implications for…

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News • Oncology

Treatment hope would leave liver cancer cells in limbo

Scientists have shown that a mutation in a gene called Arid1b can cause liver cancer. The gene normally protects against cancer by limiting cell growth, but when mutated it allows cells to grow uncontrollably. The researchers have shown that two existing drugs can halt this growth in human cells. This points to a new approach to treating liver cancer.

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News • Oncology

Nanoparticle creates ‘wave of destruction’ in cancer cells

Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer. Now, the ultrasmall particles – developed more than a dozen years ago by Ulrich Wiesner, the Spencer T. Olin Professor of Engineering at Cornell University – have shown they can do something even better: kill cancer cells without attaching a cytotoxic drug.

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News • Melanoma treatment

Dermatology develops an effective immunotherapy against solid cancer

Melanomas account among the eight most frequent deadly cancers in Europe and Northern America. Two major clinical criteria separate melanomas from most other cancers: the risk to die from a melanoma is a question of being less or more than 1 mm – and not a question of cm. About 95% of patients with melanomas ≤0.5 mm in thickness are clinically cured by early detection and appropriate melanoma…

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