News • Gene editing
Why CRISPR fails sometimes – and what to do about it
CRISPR has recently become synonymous with precise genetic editing. However, the mighty tool has been known to fail from time to time. Now, researchers have found out why.
News • High blood pressure
Millions more: New guidelines could drastically raise hypertension numbers
Adopting new guidelines for high blood pressure (hypertension) would dramatically increase the number of people labeled as having the condition and being recommended for drug treatment, finds a study published by The BMJ today. The findings show that, if the guidelines were introduced in the US and China, more than half of those aged 45-75 years in both countries would be considered hypertensive.
News • Immunotherapy response prediction
Pulling the "molecular brake" on tumor cells
An unexpected discovery that could bring new hope to cancer patients worldwide: Researchers from the University of California San Diego have identified a mechanism that could predict response to immunotherapy. The most effective weapon against the tumors may be handed to the scientists by the cancer cells themselves.
News • Infections
Zika suppresses virus fighting cells
More than two years after reports of skyrocketing Zika rates surfaced worldwide, questions still loom about this complicated virus. Professor of Biological Science Hengli Tang and his postdoctoral researcher Jianshe Lang from the Florida State University take a deep dive into the differences between Zika and the Dengue virus.
News • Anesthesiology
Low-Cost needle simulator aims to revolutionize medical training
Administering needle-based procedures in anesthesiology is a complex and delicate procedure and the current training methods for doctors are costly and fall short in preparing them. Engineers have developed a low-cost, hand-held device that simulates the tactic feeling of the instrument passing through several layers of tissue.
News • Research
'Lung on a Leaf' model to study pulmonary diseases
Researchers at the University of Arizona College of Medicine – Phoenix are cross-utilizing plant biology, medicine and engineering to create a novel platform. They have developed a revolutionary "lung on a leaf" to study pulmonary diseases.
News • Research
Unravelling the mystery of non-alcoholic fatty liver disease
Another piece in the puzzle that is non-alcoholic fatty liver disease has been solved by a University of Queensland researcher in a step towards developing treatments for a disease that affects about one in every five Australians. PhD student Laurence Britton has discovered a pivotal mechanism by which iron is able to make the liver more vulnerable to the injury and metabolic dysfunction that…
News • Research
Gene discovery unlocks mysteries of our immunity
Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.
News • Neurology
Next-gen EEG could help bring back lost brain function
SLAC and Stanford researchers are developing a device that combines electrical brain stimulation with EEG recording, opening potential new paths for treating neurological disorders. It could help bring back lost brain function by measuring how the brain responds to therapies that stimulate it with electric current.
News • Neuroscience
"Happiness hormone" controls fear memories
A team of neurobiologists has identified a novel neuronal circuit in the midbrain that gates fear learning. They think that associative learning of fear is mediated by a novel dopamine circui.
News • Promising research
Could senescence be the key to stopping cancer?
Canadian researchers have found a promising way to stop tumour cells from multiplying. In disrupting the composition of ribosomes, the team from Université de Montréal (UdeM) discovered a direct molecular mechanism to stop cancer cells from proliferating, which is called senescence. Their results have been published in Nature Cell Biology. “Ribosomes are complex machines composed of both…
News • Live long and prosper
Key molecule of aging discovered
Every cell and every organism ages sooner or later. But why is this so? Scientists at the German Cancer Research Center in Heidelberg have now discovered for the first time a protein that represents a central switching point in the aging process. It controls the life span of an individual - from the fly to the human being. This opens up new possibilities for developing therapies against…
News • Behaviour prediction
The psychology of taking risks
An anxious person will avoid risks whenever possible. This in itself is not exactly a surprise. However, researchers have found a way to visualize this process in the brain - with interesting implications for behaviour prediction. A team of psychologists from the German Friedrich Schiller University Jena, together with partners from Würzburg, Germany and Victoria, Canada they conducted an…
News • Hand in hand
Why being left-handed matters for mental health treatment
Being left-handed apparently means a lot more than gripping things differently than most, researchers find. This sheds a new light on mental health treatment, because current therapies for the most common mental health problems could be ineffective or even detrimental to about 50 percent of the population. For more than 40 years, hundreds of studies suggest that each hemisphere of the brain is…
News • Faster diagnosis, reduced cost
The impact of whole genome sequencing on newborn babys in ICU
Early whole genome sequencing might bring hope for children who are born severely ill or who develop serious illness in the first few weeks of their life. Because these children are often difficult to diagnose, detection of diseases has considerable implications for their short and longer-term care. At the annual conference of the European Society of Human Genetics (ESHG) in Milan, Italy, the…
News • Research
Unique patient offers insights into the brain's quest to see
When light streams through her window in just the right way, Milena Canning will sometimes stoop to pick up a shiny coin she has noticed on the wooden floor of her Glasgow-area home. But her hand comes up empty – the 'coin' is just a dancing sunbeam, a quirk of perception in Canning's extraordinary world.
News • Neurology
Waves move across the human brain to support memory
Biomedical engineers at Columbia Engineering have discovered a new fundamental feature of brain oscillations: they actually move rhythmically across the brain, reflecting patterns of neuronal activity that propagate across the cortex. The coordination of neural activity across widespread brain networks is essential for human cognition. Researchers have long assumed that oscillations in the brain,…
News • Research
Maps made of nerve cells
Dr. Thomas Hainmüller and Prof. Dr. Marlene Bartos of the Institute of Physiology of the University of Freiburg have established a new model to explain how the brain stores memories of tangible events. The model is based on an experiment that involved mice seeking a place where they received rewards in a virtual environment.
News • Gas embolotherapy
Blowing bubbles for cancer treatment
Recently, scientists have explored another version of embolization, called gas embolotherapy. During this process, the blood supply is cut off using acoustic droplet vaporization (ADV), which uses microscopic gas bubbles induced by exposure to ultrasonic waves. A team of researchers from China and France has discovered that these bubbles could also be used as potential drug delivery systems.
News • Analyzing free-floating DNA
Blood test shows potential for early detection of lung cancer
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. Lead study author Geoffrey R. Oxnard, MD, of Dana-Farber Cancer Institute: “There is an unmet need globally for early-detection tests for lung cancer that can be easily implemented by health-care…
News • New function assessment
Measuring immune cell response within minutes
T cells fight pathogens and tumors: Researchers from the Universities of Tübingen and Lübeck present a simple and fast method to rapidly assess their function. Due to its simplicity, reliability and versatility, it could be broadly implemented for basic research and in the clinical setting. Methods so far to test T-cell response were technically cumbersome and time-consuming and therefore only…
News • New research
Circulating tumor cells to help stage metastatic breast cancer
Menarini Silicon Biosystems announced that a new study has found that using circulating tumor cells (CTCs), a form of liquid biopsy, holds promise as a key tool for developing a staging system that can have a significant impact in the treatment of metastatic breast cancer (MBC). In this study, the largest CTCs pooled analysis study to date, researchers determined that the CTC count could be used…
News • Talent, magic, or a bit of both?
The science behind Michael Jackson’s dance moves
When was the last time you watched a Michael Jackson music video? If your answer is “never” or “not for quite a while,” you are really missing a treat. According to Rolling Stone, “No single artist … shaped, innovated or defined the medium of ‘music video’ more than Michael Jackson.” Back in the 1980s and early 1990s, MTV had only one format—music videos—and that genre…
News • Study results
Triggers of acute heart failure vary globally
Triggers of acute heart failure vary globally, according to late breaking results from the REPORT-HF registry presented at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. REPORT-HF is a global, prospective registry comparing regional differences in causes of acute heart failure, therapies, time to treatment, and outcomes. Professor Sean…
News • Hematopoietic Stem Cells
What keeps our blood in balance
Blood is the juice of life, as while circulating through the body it delivers vital substances such as oxygen and nutrients to cells and tissues. Chemotherapy, radiotherapy and blood loss in general impoverish the system. A special kind of cells in the bone marrow, called hematopoietic stem cells (HSCs) is able to replenish the impoverished system by giving rise not only to red blood cells, but…