A person’s age, sex and location are correlated with the chance that they have a bloodstream infection that is resistant to antibiotics, according to a new study.
A new approach to the identification of harmful bacteria: A new study explores how spectroscopic techniques can be used for quick analysis directly from the skin.
Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.
Smart catheters, smart diapers or wound dressings: a new approach to wireless biosensors from Malmö University opens up options for more patient-controlled ways of infection detection.
A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.
For many years, antibiotic consumption in France was at an alarming level, resulting in a worryingly constant increase in antibiotic resistance However, a newly-enforced strict national plan appears to be having effect.
To counteract the spread of resistant germs, researchers have developed new drug candidates that are able to render one of the most important hospital germs harmless.
Infectious disease diagnostics are notoriously slow. The gold standard for laboratory diagnosis of bacterial and fungal infection involves growing the pathogen from a clinical specimen – an overnight event, or even longer. The healthcare focus is on improving the use of antibiotics for better patient outcomes and reducing the environmental pressures that drive antibiotic resistance. To impact…
Antibiotic-resistant pathogens have become one of the greatest threats to public health. The basic mechanisms of resistance evolution have been well studied experimentally and are an important research field at Kiel University. An important factor in this context, but one that has received little attention so far, is the population size of the respective pathogen. Over the course of an infection…
Research has identified critical factors that enable dangerous bacteria to spread disease by surviving on surfaces in hospitals and kitchens. The study into the mechanisms which enable the opportunistic human pathogen Pseudomonas aeruginosa to survive on surfaces, could lead to new ways of targeting harmful bacteria. To survive outside their host, pathogenic bacteria must withstand various…
Researchers have developed an innovative method to disrupt the formation of biofilms and thus facilitate the treatment of infections with Pseudomonas aeruginosa.
Antibiotic-resistant pathogens pose one of the greatest threats to public health worldwide. In the near future, harmless bacterial infections may no longer be treatable and may again become the most common non-natural cause of death. At the same time, the available repertoire of antibacterial agents is becoming increasingly smaller as resistance rates rise.
Nosocomial infections cause more deaths than traffic accidents – a stunning discovery made in a recent German study. Worse: infectious diseases long thought eradicated in Europe, such as measles, tuberculosis (TB) and, more recently, syphilis, are also implicated. The increasing number of patients places an additional financial burden on healthcare. But – and this might be the good news –…
In practice, the drying of the endoscope is often underestimated and therefore a possible pitfall for hygiene and reprocessing steps. As the importance of endoscopic retrograde cholangio-pancreatography (ERCP) procedures and their impact on patients’ lives remains unwavering, the medical community is continuously looking for ways to improve this field of expertise. What better way to learn more…
Many life-threatening bacteria are becoming increasingly resistant to existing antibiotics. Swiss researchers co-headed by the University of Zurich have now discovered a new class of antibiotics with a unique spectrum of activity and mechanism of action. By disrupting outer membrane synthesis, the antibiotics effectively kill Gram-negative bacteria. According to the World Health Organization…
Scientists at the University of Surrey have discovered that a natural antioxidant commonly found in green tea can help eliminate antibiotic resistant bacteria...
Analytically sensitive and specific detection of pharmaceuticals or metabolites in bodily fluids, as well as fast and reliable detection of human pathogens, are major challenges for instrument-based analytics in medical diagnostics. Over the past few years the combination of surface-enhanced Raman spectroscopy (SERS) and microfluidic devices (Lab-on-a-Chip) has emerged as a perfectly suited…
Mariette Barbier, an assistant professor in the West Virginia University School of Medicine, and her research team are investigating ways to keep cystic fibrosis patients and other at-risk populations—including patients hospitalized for severe burns or recovering from major surgery—from catching this deadly illness.
Partners who could hardly be further apart – yet have a lot in common – have united to fight resistant pathogens. The International Consortium for Anti-Infective Research (iCAIR) is based in Germany and Australia – separated by nearly 16,000 km as the crow flies. This has not stopped the research cooperation from achieving its objectives: the development of new agents against infections.
Beta-lactam antibiotics, including penicillin, are one of the most widely used classes of antibiotics in the world. Though they’ve been in use since the 1940s, scientists still don’t fully understand what happens when this class of drugs encounters bacteria. Now, researchers at the University of Notre Dame have elucidated how an enzyme helps bacteria rebound from damage inflicted by…
Antimicrobial resistance mortality is set to surpass cancer and traffic-related deaths by 2050, according to the UK National Health Service (NHS).
Chronic lung infections caused by the bacterium Pseudomonas aeruginosa require complex and, in most cases, long-term treatment with antibiotics—new medication is badly needed.
While new agents to fight virulent pathogens are in the pipeline, a new study pinpoints where a recent addition is already being applied in the clinic.
Scientists in the UK have developed a new model that will help to advance the study of resistance to antibiotics.
Research at the University of Konstanz has identified a molecule that allows the bacterium Pseudomonas aeruginosa to inhibit its rival, Staphylococcus aureus. This might build the basis for the development of new antibiotics.
Researchers from the University of Birmingham and Newcastle University found that the unusual approach of removing antibodies from the blood stream reduced the effects of chronic infections, the requirement for days spent in hospital and the use of antibiotics.
A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections.
Microbiologists at the Universities of Münster and Nottingham, in England, have analysed an enzyme which might play an important role in the treatment of infections from the hospital germ pseudomonas aeruginosa. They have decoded the three-dimensional structure of the enzyme and revealed its function.
Australian researchers develop a new technique that tricks bacterial biofilms into dislodging from their protective matrix, making them vulnerable to treatment with antibiotics.
Curetis AG, a developer of next-level molecular diagnostic solutions, announced the successful completion of the clinical and analytical CE performance evaluation of its next-generation Unyvero P55 Pneumonia Application. The upgraded cartridge will launch at the 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID, April 25 – 28, 2015 in Copenhagen, Denmark) and is…
Cold plasma jets could be a safe, effective alternative to antibiotics to treat multi-drug resistant infections, says a study published this week in the January issue of the Journal of Medical Microbiology. The team of Russian and German researchers showed that a ten-minute treatment with low-temperature plasma was not only able to kill drug-resistant bacteria causing wound infections in rats but…
The 3-year Translational Research On Combating Antimicrobial Resistance (TROCAR) project, a consortium of 14 European institutes, has completed its first year of molecular study of high-risk antibiotic-resistant bacteria. With expertise ranging from medical microbiology to computational analysis, this network of excellence is on track to identify and target the resistant and multi-resistant…
That computer keyboards harbour bacteria is well known. Studies have determined that 3,295 germs accumulate per square inch on a standard keyboard. By comparison, a sanitary toilet has 49 germs per square inch.
Hospital acquired infections are the focus for the 3rd International Day for Fighting Infection, being marked on St. George’s Day (23 April), as experts meet in Florence to look at the evolution of infection control in hospitals.
In November 2009 about 150 leading infectious disease researchers gathered in Berlin for the National Forum for Innovation in Medicine. During the meeting, Professor Antoni Torres MD (Hospital Clinic-Ciberes, University of Barcelona) gave Meike Lerner insights into community acquired pneumonia research projects and findings
The first strain of methicillin resistant Staphylococcus Aureus (MRSA) was isolated in the 1960s, and its presence was reported worldwide in the late 1990s. A higher incidence of MRSA was noted in communities, at the dawn of the new millennium, leading to two basic MRSA strains being differentiated - CA-MRSA (community acquired MRSA) and HA-MRSA (healthcare associated MRSA). In clinical practice…
That tap water carries pathogens such as legionella or pseudomonas aeruginosa is well known, writes Heidi Heinhold. However, new research results show that bacteria that were previously considered non-pathogenic, such as coagulase-negative staphylococci (CONS), can be present in hospital water and are transmitted by the water
Every day, patients are admitted to surgeries, hospitals and outpatient clinics with chronic wounds. Careful inspection gives a wound therapist clues to the appropriate primary care required even before further diagnostic procedures are carried out. So what do the clinical signs and symptoms tell us? Report: Heidi Heinold
Hospital acquired infections affect about half a million people annually, and water is a serious source of infection.
Is a sharp weapon being blunted? Article by Heidi Heinhold.