News • Arthroplasty
Patients with risk factors benefit from COPAL G+C
New studies demonstrate benefits of dual antibiotic-loaded bone cement (COPAL G+C) to reduce periprosthetic joint infections in risk for infection patients.
Therapy
Aducanumab
FDA grants accelerated approval for Alzheimers drug
The U.S. Food and Drug Administration approved Aduhelm (aducanumab) for the treatment of Alzheimer’s, a debilitating disease affecting 6.2 million Americans. Aduhelm was approved using the accelerated approval pathway, which can be used for a drug for a serious or life-threatening illness that provides a meaningful therapeutic advantage over existing treatments.
News • TARGIT-IORT
Pioneering single-dose radiotherapy for breast cancer treatment
A breast cancer therapy that requires just one shot of radiotherapy is as effective as traditional radiotherapy, and avoids potential damage to nearby organs, according to a paper by UCL experts.
News • Parkinson’s disease
An algorithm for next-gen deep brain stimulation devices
Brown University researchers have developed a technique that could allow deep brain stimulation devices to sense activity in the brain and adjust stimulation accordingly.
News • Battle for the brain
New Alzheimer's treatment approach targets tau
A new idea for treating Alzheimer’s disease could eradicate the toxic proteins most closely linked to cognitive decline in the places where they do the most damage, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests. The study was published online in Science Translational Medicine.
News • New cardiology approach
Super saturated oxygen therapy reduces consequences of heart attack
In Germany, more than 200,000 people suffer a heart attack every year. Despite good medical care, many are left with reduced cardiac output. This is particularly true for patients with severe heart attacks: more than 30 percent of those affected develop heart failure, and almost half of them die within the next five years. Experts at the Department of Cardiology and Angiology at Hannover Medical…
News • Prevention, treatment, care and support
Action on stroke: Experts launch joint declaration
An appeal is launched for Health Ministries across Europe to sign the Declaration for Action on the Stroke Action Plan for Europe to tackle one of the leading causes of death and disability. Led by The European Stroke Organisation (ESO) and Stroke Alliance for Europe (SAFE), the initiative aims to encourage European countries to show their commitment to improving stroke prevention, treatment,…
News • Headache
Chronic migraine: potential novel treatment discovered
By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine. Amynah Pradhan, associate professor of psychiatry at the University of Illinois Chicago, is the senior author of the study, whose goal was to identify a new mechanism of chronic migraine, and propose a cellular pathway for migraine therapies. The study, “Neuronal…
News • Vision for vision
Reversing blindness: Award for cone optogenetics gene therapy
The Foundation Fighting Blindness has granted 600,000 US$ to help Hendrik Scholl as principal investigator define a novel way of reversing blindness. Hendrik Scholl is Director of the Institute of Molecular and Clinical Ophthalmology Basel (IOB), Professor and Chairman of the Department of Ophthalmology, University of Basel, and Head of the University Hospital’s Eye Clinic in Basel, Switzerland.
News • Cost-effective and efficient
Thanks to shrub, 'undruggable' cancer protein becomes druggable
A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.
News • Cancer research
'Gene ferry' improves immune therapies
Genetically enhancing a patient's immune cells by adding therapeutic genes to them outside the body is regarded as a promising new treatment approach in oncology. However, the production of these therapeutic cells using viruses is not only expensive but time-consuming. Researchers at the German Cancer Research Center (DKFZ) have developed an innovative non-viral vector that can efficiently…
News • Intrahepatic cholangiocarcinoma
A new approach for treating bile duct cancer
Intrahepatic cholangiocarcinoma (ICC) develops within the liver. With one to two cases per 100,000 inhabitants in Germany, ICC is one of the rare diseases overall, but it is the second most common liver cancer. The aggressive bile duct tumour remains clinically inconspicuous for a long time, so that it is often only detected late. Because the tumour also only responds to chemotherapy to a limited…
News • Coronavirus
COVID-19: Enzyme blocks immune response to infection
Researchers from Cleveland Clinic’s Florida Research and Innovation Center (FRIC) have identified a potential new target for anti-COVID-19 therapies.
News • Nueva sigla para crear más conciencia acerca de los ataques cerebrales
¿Sospecha de accidente cerebrovascular? actua 'RÁPIDO'
Los investigadores acaban de establecer un nuevo acrónimo en español con el objetivo de crear un mayor nivel de conciencia en la comunidad hispana acerca de los síntomas de los ataques cerebrales. Conocido como RÁPIDO, la intención de este nuevo acrónimo es replicar el equivalente popular que existe en inglés de FAST. En los estudios se ha mostrado que hoy en día los adultos hispanos…
News • A BOLD-100 approach
Novel metallodrug shows promise in tumour treatment
BOLD-100/KP1339 is a ruthenium-based anticancer agent that has been co-developed at the University of Vienna and which has shown promising results in clinical trials in cancer patients. However, the mode of action of this metal compound has not yet been fully elucidated. Researchers from the University of Vienna and the Medical University of Vienna have now been able to demonstrate that BOLD-100…
News • Immersion is key
Hemodialysis: Virtual reality lessens side effects
Hemodialysis patients routinely experience side effects such as fatigue, lightheadedness and nausea during their treatment sessions. But patients in a study who used a virtual reality program to engage in a mindfulness/meditation exercise reported that these treatment-related symptoms were greatly reduced. Patients in the study wore a head-mounted virtual reality display to participate in a…
Article • Experimental therapy
CRP apheresis: First successful treatment of Covid-19 patient
Apheresis, a procedure that separates and removes particular blood constituents, shows promise for Covid-19 cases: the first patient successfully underwent so-called CRP apheresis, which can prevent potentially fatal consequences of the infection.
News • Survival prediction
Deep learning may lead to better lung cancer treatments
Doctors and healthcare workers may one day use a machine learning model, called deep learning, to guide their treatment decisions for lung cancer patients, according to a team of Penn State Great Valley researchers. In a study, the researchers report that they developed a deep learning model that, in certain conditions, was more than 71% accurate in predicting survival expectancy of lung cancer…
News • A closer look at thapsigargin
Potential antiviral treatment for Covid-19 found
Researchers from the University of Nottingham have discovered a novel antiviral property of a drug that could have major implications in how future epidemics/pandemics – including Covid-19 – are managed. The study, published in Viruses, shows that thapsigargin is a promising broad‑spectrum antiviral, highly effective against SARS-CoV-2, a common cold coronavirus, respiratory syncytial virus…
News • Five things you need to know
Delaying the gap between COVID-19 vaccine doses
As the first coronavirus vaccines started to be rolled out at the end of a tumultuous 2020, UK officials unexpectedly endorsed stretching the gap between the first and second vaccine dose by up to three months – an approach also considered by other countries.
News • Valid for breast as well as blood cancers
Surprising benefits discovered in new cancer treatment
One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research. “The results provide more justification and rationale for starting the clinical trial in May,” said first author John Mackey, professor and director of oncology clinical…
News • Osteoarthritis research
New treatment target could halt knee cartilage degeneration
There is currently no cure for osteoarthritis, but a group of scientists believe they’ve discovered a method through which a simple knee injection could potentially stop the disease’s effects. These researchers showed that they could target a specific protein pathway in mice, put it into overdrive and halt cartilage degeneration over time. Building on that finding, they were able to show that…
News • Lasts longer, causes more damage
Covid-19 pneumonia: not your typical garden-variety pneumonia
Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body’s immune system within the first few days of the illness. But in a study published in Nature, investigators at Northwestern Medicine show Covid-19 pneumonia is…
News • Alternative to traditional surgery
Focused ultrasound shows promise for Parkinson’s treatment
A scalpel-free alternative to brain surgery has the potential to benefit people with Parkinson’s disease symptoms that are much more severe on one side of the body, new research suggests. More testing is needed, but the approach, which uses a technology called focused ultrasound, could offer a new option for patients whose symptoms are poorly controlled by medications and those who cannot or do…
News • Radiation
Scientists recruit atomic heavyweights in fight against cancer
A promising approach to treating cancer—called targeted alpha-particle therapy or TAT—could better harness the curative power of radiation treatments and lessen the severity of their more debilitating side effects.
