A clinical trial involving hundreds of participants has shown that one of the most frequently prescribed antidepressants may not benefit millions of patients who also have chronic kidney disease (CKD). “These results provide evidence that could change clinical practice,” said Dr. Susan Hedayati, Professor of Internal Medicine at UT Southwestern and first author of the study, which was…
Patients with advanced breast cancer who are treated with a combination of drugs that target specific molecules important for cancer development and also the hormones that are driving it are at increased risk of suffering adverse side effects. In new research presented at the Advanced Breast Cancer Fourth International Consensus Conference (ABC 4), researchers have shown that combining targeted…
Taking part in regular exercise can reduce fatigue and pain, and improve cardiovascular health and quality of life in women being treated for advanced breast cancer, according to new research presented at the Advanced Breast Cancer Fourth International Consensus Conference (ABC 4). Hundreds of thousands of women around the world are being treated for advanced breast cancer, where the tumour has…
Patients with advanced breast cancer have a better quality of life for longer if the progression of their disease can be delayed, according to new results presented at the Advanced Breast Cancer Fourth International Consensus Conference (ABC 4) in Lisbon. Professor Nadia Harbeck, head of the Breast Cancer Centre at the University of Munich (Germany), told the meeting that analysis of results from…
A Stanford study of nearly 24,000 patients with kidney cancer concluded that robot-assisted laparoscopic surgeries are associated with increases in operating times and cost compared with conventional laparoscopic surgeries. However, the two approaches have comparable patient outcomes and lengths of hospital stay, the study showed.
The Russian biotechnology company Biocad plans to enter the European market with oncological and autoimmune medicines. So far, there are seven molecules in the European portfolio of Biocad. The biosimilar products could be used in treatment of melanoma, breast, stomach, kidney and lung cancer, rheumatoid arthritis, psoriasis and multiple sclerosis.
Heart surgery significantly decreases in-hospital mortality among infants with either of two genetic disorders that cause severe physical and intellectual disabilities, according to a new study by a researcher at the Stanford University School of Medicine and his colleagues at the University of Arkansas for Medical Sciences. Trisomy 13 and 18, which result from having extra chromosomes, often…
A new study found that increased utilization of split liver transplantation could decrease the number of children who die awaiting liver transplantation without decreasing liver transplantation access for adult patients. “Among children listed for liver transplant in the United States, more than one in 10 infants and one in 20 older children die while waiting for a liver,” says Emily Perito,…
University of Alabama at Birmingham biomedical engineers report a significant advance in efforts to repair a damaged heart after a heart attack, using grafted heart-muscle cells to create a repair patch. The key was overexpressing a gene that activates the cell-cycle of the grafted muscle cells, so they grow and divide more than control grafted cells.
There is no “one size fits all approach” when it comes to treating breast cancer. The disease is made up of several subtypes, and ideally each type should be treated with therapies that target the unique underlying biological problems. Fortunately, for the past 25 years, long-term survival and cure rates have significantly improved for women with breast cancer. This is due in large part to…
The majority of cancer drugs approved in Europe between 2009 and 2013 entered the market without clear evidence that they improved survival or quality of life for patients, finds a study published by The BMJ. Even where drugs did show survival gains over existing treatments, these were often marginal, the results show. Many of the drugs were approved on the basis of indirect (‘surrogate’)…
Today, many congenital heart defects can be diagnosed in the unborn child – and even treated in utero. Monique Haak (46), gynaecologist-perinatologist and fetal surgeon at Leids University Medical Center (LUMC) in Leiden, The Netherlands, is an expert in the diagnosis and surgery of fetal heart defects.
Combining a new compound with old drugs could provide an effective remedy against malaria and drug-resistant parasites.
Pentax Europe, a healthcare industry leader in endoscopic imaging, and Hitachi Medical Systems Europe, a leading company in medical imaging, recently announced renewed joint collaborative efforts to enable further innovations in the development of endoscopic ultrasound (EUS). In this latest joint development, the two companies are launching a new ultrasound video bronchoscope for endobronchial…
Electrospun materials bring a spark of hope to a cardiovascular landscape darkened by setbacks for reabsorbable stents. It was famously said that implanting a device in a person to cure a disease is to implant a new disease. Simply put, the human body will continually fight against foreign materials, leading to chronic inflammations or repeated interventions.
Scientists in the United Kingdom are investigating the potential of a new regenerative and tissue engineering technique that could transform veins into arteries to improve the outcomes for patients undergoing heart bypass surgery.
Shielding cardiologists from harmful radiation is the goal for two systems capable of navigating the vascular highway.
A Spanish team has, for the first time, successfully placed a pulmonary valve using catheterisation through the hepatic vein in a paediatric patient. Specialists believe this type of intervention could become an interesting alternative when traditional access points are not available.
Which CRT patients can be ‘downgraded’ from a CRT-D device with defibrillator function to a CRT-P with just a pacemaker function? This, with two further current CRT issues – chronotropic incompetence and telemonitoring of CRT patients – featured prominently at the Europace-Cardiostim Congress in Vienna.
A formerly bitter competition between cardiology and cardiac surgery is increasingly replaced by constructive cooperation. The Austrian Society of Cardiology (ÖKG) even held its annual congress along with the Austrian Society of Thoracic and Cardiovascular Surgery this year.
Coronary angioplasty is arguably the most revolutionary breakthrough in the history of cardiology. While the technique is today performed on millions of patients worldwide, its origins can be traced back to Zurich, Switzerland, in the late 1970s.
Every cancer is different and every patient is different. This insight gained in personalised medicine prompted oncology researchers to focus more on the individual patient’s immune system. It is particularly the immune system’s ability to destroy cancer cells that raised hope.
Computer scientist Stefanie Speidel, who became a Professor for Translational Surgical Oncology at the National Centre for Tumour Diseases, in Dresden in Germany this April, researches intelligent assistance systems for the operating theatre.
A team from Michigan Medicine developed a health behavioral intervention called Reach Out including mobile-messaging components, which they plan to use throughout a trial.
One in four patients in a university hospital suffers from diabetes (22 percent), and again as many suffer from prediabetes (24 percent), a current study finds. Furthermore, patients with diabetes have prolonged hospital stays and a higher risk of complications.