Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a “one-size-fits-all” cancer therapy. T-cell therapies for cancer - where immune cells are removed, modified and returned to the patient’s blood to seek and destroy cancer cells - are the latest paradigm in cancer treatments. The most widely-used therapy, known as CAR-T, is personalised to each…
A technique that enables patients suffering from heart conditions to hold their breath safely for over 5 minutes could have potential as part of a new treatment for cardiac arrhythmias, say researchers at the University of Birmingham. In a new study, published in Frontiers in Physiology, researchers initially proposed the technique as a new means for earlier diagnosis of ischaemic heart disease.…
Patients have come to expect a technician to drape their torsos with a heavy lead apron when they get an X-ray, but new thinking among radiologists and medical physicists is upending the decades-old practice of shielding patients from radiation.
How can the treatment of soft tissue sarcomas, these particularly resistant and aggressive forms of cancer, be improved and better personalized? An international team led by Wolf Hervé Fridman with researchers from Inserm, Sorbonne Université and Université de Paris at the Cordeliers Research Center, in collaboration with the French League against cancer and Institut Bergonié, has shown that…
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week. This breakthrough may increase the number of available organs for transplantation, saving many lives of patients with severe liver diseases or cancer. Until now, livers could be stored…
Patients with colorectal cancer have a greater chance of survival if they are operated in hospitals with a high case load. This is because complications that can occur after surgery can be better managed there. Tumours of the colon, so-called colorectal carcinomas, are the second to third most frequent tumours in women and men in Germany. The surgical removal of the tumours is a central component…
Researchers at Lund University in Sweden have developed a new hydrogel based on the body’s natural peptide defense. It has been shown to prevent and treat infections in wounds. The formulation kills multi-resistant bacteria, something that is increasing in importance with antibiotic resistance growing globally. “The ability to effectively heal wounds is key for our survival in evolutionary…
Doctors have used focused ultrasound to destroy tumors in the body without invasive surgery for some time. However, the therapeutic ultrasound used in clinics today indiscriminately damages cancer and healthy cells alike. Most forms of ultrasound-based therapies either use high-intensity beams to heat and destroy cells or special contrast agents that are injected prior to ultrasound, which can…
Using a computer algorithm, scientists at Uppsala University have identified a promising new treatment for neuroblastoma. This form of cancer in children, which occurs in specialised nerve cells in the sympathetic nervous system, may be life-threatening. In the long term the discovery, described in the latest issue of the scientific journal Nature Communications, may result in a new form of…
Modern healthcare without hand hygiene? Inconceivable – particularly in the operating room (OR). But what happens when it is not the surgeon who handles the scalpel, but a robot? Robotic surgery, just like surgery performed by humans, always carries a risk of microbial transmission to the patient, says Professor Johannes K-M Knobloch of University Hospital Hamburg-Eppendorf (UKE). A specialist…
The Protestant Hospital Wesel (EVK Wesel) is one of two reference centres in Germany and one of 25 worldwide for the Senhance Surgical Robotic System from Transenterix. ‘We wanted to be the first in the Lower Rhine region to go to market with a robotic system as we believe that this type of digital surgical assistance represents the future,’ explains Rainer Rabsahl, CEO of the 356-bed…
An exciting development from an innovative French company is poised for a major breakthrough in European markets. As is now well-known, coronary angioplasty is a procedure that widens and/or unblocks the arteries to the heart by the insertion and inflation of a balloon and/or stent into the vessel lumen. In modern practice, a stent is normally left in place to ensure the blood flow remains…
Periprosthetic joint infection (PJI) is on the increase internationally. In Germany, for example, around 14,500 cases of PJI in hip and knee replacements occur annually. 5,100 of those are caused by multidrug resistant pathogens. ‘Eighty-seven percent of those affected die within five years,’ orthopaedic surgeon Professor Rudolf Ascherl MD pointed out during the Heraeus Symposium held at the…
War wounds sustained by frontline soldiers or civilians usually need urgent, specialist, trauma surgery. Over the last two decades much has been learned from injuries sustained during conflicts in, for example, Afghanistan and Iraq. In early June, during a Catastrophe and War Wound key session at the European Wound Management Association conference in Gothenburg, specific remedial approaches to…
A medicine that could control outbreaks of scabies in the UK is unlicensed and only available through specialist importers, researchers at Brighton and Sussex Medical School (BSMS) have found. In July 2019, the World Health Organization (WHO) updated its model list of essential medicines to include oral ivermectin for scabies-related infections. This recommendation follows the 2017 WHO…
A new multicentre study will investigate the link between brain inflammation and psychosis, and use artificial intelligence techniques to identify patients that might benefit most from novel treatments. The study, funded by UKRI Medical Research Council, is led by the Universities of Birmingham and Cambridge. Researchers will examine how and if activated inflammatory cells may act differently in…
An enthralling insight into the care that could be offered to cancer patients of the future was presented by cancer imaging expert Professor Regina Beets-Tan during her a keynote presentation at the recent British Institute of Radiology congress. In the session ‘Oncologic imaging: Future perspectives’, the professor outlined what a Multi-Disciplinary Team (MDT) of the future – a team in…
Robocath, a company that designs, develops and commercializes cardiovascular robotic systems for the treatment of vascular diseases, announced it has successfully completed six robotic coronary angioplasties with R-One, a first for the continent of Africa. The Percutaneous Coronary Interventions (PCI) were performed by Dr Faizel Lorgat, an interventional cardiologist at the Netcare Christiaan…
For the early detection of colorectal cancer, patients with statutory health insurance are entitled to two colonoscopies. If the first examination does not reveal any abnormal findings, a follow-up after a period of ten years is recommended. Scientists at the German Cancer Research Center are now systematically investigating when and how often tissue lesions are detected during the follow up…
Dr Ganesh Bavikatte, Neurorehabilitation Specialist, has developed a solution along with an international expert team to untangle the complex post-stroke spasticity care pathway. With Europe’s ageing population, stroke cases are on the rise, with estimates suggesting around a 35% increase from the number of cases in 2015 to 2035. And thanks to the greatly improved emergency care and delivery of…
A new effective treatment of hepatitis C that was made available to all Danes last year, not only combats the virus, but is also effective against potentially fatal complications such as reduced liver functioning and cirrhosis. This is the result of a new study from Aarhus University and Aarhus University Hospital. Hepatitis C is a serious disease, but the biggest threat to someone’s health is…
A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new University of Liverpool research warns. Published in the journal mBio, the findings highlight the need to develop new drugs and treatment regimens for the lethal brain infection, which kills around 180,000 people each year. Cryptococcal…
The U.S. Food and Drug Administration (FDA) announced the global launch of Cure ID, an internet-based repository that will allow the clinical community to report their experiences treating difficult-to-treat infectious diseases with novel uses of existing FDA-approved drugs through a website, a smartphone or other mobile device. The platform enables the crowdsourcing of medical information from…
Medication prescribed for a certain type of epilepsy may offer a new method for treating malignant infantile brain tumours. A specific mTOR inhibitor has the ability to cross the blood–brain barrier to both reach and attack the tumour at source. This has been demonstrated by researchers from Uppsala University, in collaboration with US and UK colleagues, whose research has now been published in…
Obesity not only means someone is overweight but, over time, they will probably suffer sequelae that increasingly impair quality of life and are potentially fatal – these include hypertension, coronary heart disease, type two diabetes, pulmonary function disorders, tumours, plus an increased risk during surgery and anaesthesia. In patients with morbid obesity, class three obesity, according to…