Sponsored • Invitation
Making health data actionable
In an online event on June 24th, international experts will discuss how a joint European Health Data Space is supposed to drive innovation and medical progress.
Research
News • Longevity
One for all: Convergent mechanism of ageing discovered
Researchers have discovered folate metabolism as a fundamental process for ageing. This could provide a new opportunity to improve human health during ageing on a broad basis.
News • Severe effects
How COVID-19 wreaks havoc on human lungs
Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have published the first detailed atomic-level model of the SARS-CoV-2 "envelope" protein bound to a human protein essential for maintaining the lining of the lungs.
News • Bacteriophage
Trained viruses fight antibiotic resistance
A new project led by University of California San Diego Biological Sciences graduate student Joshua Borin has provided evidence that phages that undergo special evolutionary training increase their capacity to subdue bacteria.
News • Immune system
Fundamental advance in understanding T cell immunity
Monash University researchers have provided a fundamental advance regarding how T cells become activated when encountering pathogens such as viruses.
News • Covid-19
Rapid blood test detects vaccination
A team of Johns Hopkins researchers has developed a rapid blood test that could confirm a person has been vaccinated while they wait to board a plane or enter a sporting event.
News • In mice
Researchers increase life expectancy by an average of 30%
Researchers have shown that the life expectancy of mices can be increased by an average of 30% in both males and females. For humans, that would means that a 90-year-old could live until nearly 120.
News • Good news
Mild COVID-19 induces lasting antibody protection
Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.
News • Molecular research
How retroviruses become infectious
Understanding every step in the life cycle of a virus is crucial for identifying potential targets for treatment. Now, scientists at the Institute of Science and Technology (IST) Austria were able to show how a virus from the retrovirus family – the same family as HIV – protects its genetic information and becomes infectious. Furthermore, they show an unexpected flexibility of the virus. This…
News • Neuroscience
A deep dive into the brain
Researchers from ETH Zurich and University of Zurich have developed a new microscopy technique that lights up the brain with high resolution imagery. This allows neuroscientists to study brain functions and ailments more closely and non-invasively.
News • Promising protein "MARK4"
Switching off heart protein could protect against heart failure
Switching off a heart muscle protein could provide a new way for drugs to combat heart failure in people who’ve had a heart attack, according to research led by the University of Cambridge and published in the journal Nature. There is an unmet need to find drugs that can successfully improve the heart’s ability to pump blood efficiently after it’s been damaged following a heart attack.…
News • Stress, depression, anxiety
Suppress or sustain? How our brain handles traumatic memories
Two clusters of brain cells compete to promote either the persistence or disappearance of traumatic memories, according to a new study conducted in mice. The findings could provide important insights into human conditions such as post-traumatic stress disorder (PTSD), anxiety disorders, and associated problems such as alcohol use disorder (AUD) that can arise from the persistence of traumatic…
News • Battle for the brain
New Alzheimer's treatment approach targets tau
A new idea for treating Alzheimer’s disease could eradicate the toxic proteins most closely linked to cognitive decline in the places where they do the most damage, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests. The study was published online in Science Translational Medicine.
News • „Swarm Learning“
AI with swarm intelligence to analyse medical data
Communities benefit from sharing knowledge and experience among their members. Following a similar principle - called “swarm learning” - an international research team has trained artificial intelligence algorithms to detect blood cancer, lung diseases and Covid-19 in data stored in a decentralized fashion. This approach has advantage over conventional methods since it inherently provides…
News • Disease of smallest heart blood vessels
Microvascular angina: the global health problem you've never heard of
For the first time, a prospective, international study has shown that chest pain caused by problems with the very small vessels supplying blood to the heart is an important health problem that increases the risk of heart attacks, stroke and death due to cardiovascular reasons. The study, which is published in the European Heart Journal, recruited 686 patients from 14 institutions in seven…
News • Pancreatic ductal adenocarcinoma (PDAC)
Cutting-edge approach to fighting deadly form of pancreatic cancer
By 2030, the most lethal form of pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC), is projected to become the second leading cause of cancer-related deaths in the United States. Not only are therapeutic options limited, but nearly half of PDAC patients who have their tumors removed surgically experience disease recurrence within a year, even with chemotherapy. For more advanced stages,…
News • Targeted drug delivery
'Soft X‑ray' method opens up ways for smart nano-medicine
Before the huge potential of tiny nanocarriers for highly targeted drug delivery and environmental clean-up can be realized, scientists first need to be able to see them. Currently researchers have to rely on attaching fluorescent dyes or heavy metals to label parts of organic nanocarrier structures for investigation, often changing them in the process. A new technique using chemically-sensitive…
News • Corona in healthcare workers
Covid-19 and hospital staff: many infections, but few re-infections
A study of healthcare workers shows they were three times more likely to become infected during the Covid-19 pandemic compared to the general population. Around one in five of workers who were infected were asymptomatic and unaware they had Covid-19. The study published in ERJ Open Research also shows that it was not only frontline staff who faced the higher risk, suggesting that there was…
News • Coronavirus research
Novel defense mechanism for SARS-CoV-2 discovered
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune response in COPD patients.
News • Heartbeat in a dish
"Cardioids" hold great promise for heart disease research
Self-organizing heart organoids – developed at the Austrian Academy of Sciences – are also effective injury- and in vitro congenital disease models. These “cardioids” may revolutionize research into cardiovascular disorders and malformations of the heart. The results are published in the journal Cell.
News • Coronavirus complications
Post-acute Covid: study explores risk of developing long term conditions
One in 7 (14%) adults with coronavirus infection developed at least one new condition that required medical care during the post-acute phase of illness, which is 5% higher than adults with no coronavirus infection in 2020, finds a US study published by The BMJ. The post-acute phase in this study started 21 days (or 3 weeks) after initial infection.
News • Victims of the pandemic
Covid-19 death toll: experts estimate 1 million excess deaths
Almost 1 million extra deaths relating to the Covid-19 pandemic occurred in 29 high income countries in 2020, finds a study published by The BMJ. Except for Norway, Denmark and New Zealand, all other countries examined had more deaths than expected in 2020, particularly in men. The five countries with the highest absolute number of excess deaths were the US, UK, Italy, Spain, and Poland.
News • Neuroscience
Potential new approach for epilepsy control
Researchers from Case Western Reserve University have identified a potential new approach to better controlling epilepsy. Lin Mei, professor and chair of the Department of Neurosciences at Case Western Reserve School of Medicine, who led the new study in mouse models, said the team found a new chemical reaction that could help control epileptic seizures.
Article • Cardiac care to go
Wearables in cardiology: from activity monitoring to research support
Activity monitors via phones and bracelets help to assess exercise but experts question which device may really stimulate activity in cardiovascular patients, and which might be best for research?
Article • Digital pathology
Today’s tissue for tomorrow’s research
Specialist biorepositories are helping advance personalised medicine by supporting the availability of human tissue for research using digital pathology techniques. The pivotal role of the Glasgow Tissue Research Facility (GTRF) in making tissue available to shape new therapies and treatments was outlined in a presentation to the online “Transforming Digital Pathology – Integrating AI to Move…