Research

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Colder days raise the risk of more heart attacks

In the light of global climate change, the relations between weather and health are of increasing interest. A drop in the average temperature outside is linked to a higher risk of people having heart attacks, according to a new study published on bmj.com today. UK researchers found that each 1°C reduction in temperature on a single day is associated with around 200 extra heart attacks.

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46th EASD Annual Meeting

Professor Claes-Göran Östenson, chair of the Local Organising Committee of the 46th European Association for the Study of Diabetes annual meeting, will welcome visitors in this the bicentenary year of the renowned Nobel-prize giving Karolinska Institute. Since its foundation in 1965, the EASD annual meeting has become the world’s largest international annual conference on diabetes research,…

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Seeking the genetic basis of diabetes

Researchers have identified 12 new genes associated with Type 2 diabetes (T2D) that look set to improve the understanding of the processes underpinning the condition. The findings could also offer new biological pathways that can be explored as targets for new therapies to tackle T2D.

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Warning: Staff may fail to spot suicide risk

Previous research has indicated that the emergency department might be well-placed to pick up patients vulnerable to suicide. However, according to a small, new study carried out by researchers at Manchester University, although people who frequently present themselves at hospital emergency departments may be at high risk of suicide, emergency care staff may fail to spot their vulnerability.

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A bright future for biobanks

Ten years ago, molecular biologist Dr Peter H J Riegman set up a unique bio-bank for medical research at the pathology department of Erasmus Medical Centre, Rotterdam, The Netherlands. The Erasmus MC Tissue Bank now holds 30,000 samples from about 15,000 patients. However, when Dr Riegman discusses his bio-bank with international colleagues they do not immediately associate it with a clinic or…

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The Heinz Nixdorf Recall Study

Initiated in 1999, the Heinz Nixdorf Recall Study involved 4,814 European participants. The results proved, for the first time, the connection between coronary calcifications and the risk of heart attack, according to scientists at the University Hospital in Essen. The finding by no means exhausted the potential inherent in the surveys. Subsidised until 2013, researchers are examining coronary…

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Diabetes doubles CVD risk

A team led by UK-based researchers has found that having diabetes doubles the risk of developing a wide range of blood vessel diseases, including heart attacks and different types of stroke. The consortium, headed by Dr Nadeem Sarwar and Professor John Danesh of the University of Cambridge, analysed data from the individual records on 700,000 people, each of whom was monitored for about a decade…

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When is our hand not our hand?

When we look at our hands, how do we know they are part of our body? This seems like a strange question because it is something most of us take for granted. Exciting new data from a research group at the Karolinska Institutet in Sweden show that the brain uses a combination of sensory signals from our eyes and limbs to achieve a sense of ‘body ownership’.

TROCAR is on track

The 3-year Translational Research On Combating Antimicrobial Resistance (TROCAR) project, a consortium of 14 European institutes, has completed its first year of molecular study of high-risk antibiotic-resistant bacteria. With expertise ranging from medical microbiology to computational analysis, this network of excellence is on track to identify and target the resistant and multi-resistant…

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Advanced melanoma

An increase in survival in metastatic melanoma – the cancer with the most rapidly increasing incidence across the EU – has been shown for the first time in a major international study by researchers from across Europe. The results showed that patients who received a novel monoclonal antibody called ipilimumab lived 34% longer than control patients given gp100 peptide vaccine.

Multiple Sclerosis drugs scheme ‘a costly failure’

A multiple sclerosis risk sharing scheme, set up by the Department of Health (DoH) in 2002 to ensure that disease-modifying drugs were available on the National Health Service (NHS), has been deemed ‘a costly failure’, according to researchers reporting on www.bmj.com in June. The scheme, they advise, should not be continued.

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Type 2 diabetics have elevated risk of 24 types of cancer

Type 2 diabetics run an elevated risk of developing cancer, according to the world’s largest study on the combined risk of diabetes and cancer, conducted by scientists at the German Cancer Research Centre (DKFZ). The study focused on 24 types of cancer. The effect is most evident for liver cancer and pancreatic cancer. However, by contrast, diabetics have a significantly lower rate of prostate…

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Insulin without patent protection

A new method to produce insulin cheaply has been developed by researchers at the Helmholtz-Centre for Infection Research (HZI) in Braunschweig, in a German-Indo collaboration. The group’s results are published in the open access online research magazine Microbial Cell Factories. The data is freely accessible by anyone and is not subject to patent law.

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3-D endoscopy for image guided surgery

Segmental liver resections and ablative therapies require accurate and precise tumour localization. Because the peritoneal cavity is subject to deformations caused by respiration and topological changes in the surgical site during an intervention, the transfer of MRT and CT tumour data into an intra-operative setting remains a technical challenge.

Cancer tumours that fight themselves

Cancer cells producing toxins that destroy tumours – could this be a future treatment for cancer? Researchers at Lund University have achieved good results in tests on both cells and animals. The results have now been presented in the respected scientific journal Cancer Research.

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Article • Diagnosis, Management, Treatment

EPDA Champions Change for People with Parkinson’s Disease in Europe

To mark the first European Parkinson’s Action Day on April 12th, the European Parkinson’s Disease Association (EPDA) announced the launch of a major new investigation into the care of people with Parkinson’s across 36 European countries. Parkinson’s disease is the second most common progressive neurodegenerative condition which affects people from all around the world.

Study unravels the hidden genomic complexity of the giant mimivirus

A study published online today in the journal Genome Research offers surprising new clues into the genomic complexity of the giant Mimivirus, the largest known virus in the world. Previous studies have shown that unlike most viruses, the Mimivirus has more genes than many bacteria and performs functions that normally occur only in cellular organisms. The results of the most recent study, led by a…

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The European Network for Cell Imaging and Tracking Expertise (ENCITE)

Since June 2009, the focus of research in the European Network for Cell Imaging and Tracking Expertise (ENCITE) has been on finding biomarkers to aid cell transplantation. Funded with €11 million from the European Commission (EC), this major project that runs until 2013, involves 10 countries. Their work is coordinated by the European Institute for Biomedical Imaging Research (EIBIR) network,…

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