Cells

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News • Therapy

New way to predict COPD progression

New research has found that a process initiated in white blood cells known as neutrophils may lead to worse outcomes for some patients with chronic obstructive pulmonary disease (COPD). The discovery may help identify patients at higher risk for COPD progression, who might also show little benefit from standard treatments.

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News • Breakthrough

Gut bacteria drive growth of stem cells in colon cancer

Colon cancer is one of the most common forms of cancer in Germany. Prof. Dr. med. Sebastian Zeißig, group leader at the DFG Research Center for Regenerative Therapies Dresden (CRTD) - Cluster of Excellence at the TU Dresden and physician at the Department of Medicine I, University Hospital Carl Gustav Carus Dresden, has now shown a decisive role of gut bacteria in the regulation of intestinal…

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News • Immune system

How can two types of immune cells arise from one?

The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children’s Research Hospital have discovered that the production of daughter cells with different roles in the immune system is driven by the lopsided distribution of the signaling protein c-Myc. Nudging c-Myc in one direction or the other could make vaccines more effective or advance…

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News • MOZART

Imaging cells and tissues under the skin

Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal.

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News • Head and neck

Imaging scans track down persistent cancer cells

Head and neck cancer patients may no longer have to undergo invasive post-treatment surgery to remove remaining cancer cells, as research shows that innovative scanning-led surveillance can help identify the need for, and guidance of, neck dissection. The study from the Universities of Birmingham and Warwick and University Hospitals Coventry and Warwickshire used advanced imaging to identify…

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News • MS

How do immune cells enter the cerebrospinal fluid?

A research team headed by scientists at the Institute of Neuroimmunology and the Institute for Multiple Sclerosis Research (IMSF), University Medical Center Göttingen (UMG), has gained new insights into the immune function of cerebrospinal fluid (CSF). They used real-time microscopy to film the lively trafficking of immune cells between the CSF and the nervous tissue. Here the meninges play the…

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News • heat-shock

HSF1 – in case of emergency

When there is an accident or a house fire, we call the police or the fire services. A control room quickly coordinates emergency operations. The cells in our bodies also have helpers in a crisis; the heat-shock proteins. These are triggered in response to cellular stress, such as high temperature, UV radiation or cancer. Heat-shock proteins help other proteins maintain their functional structure…

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News • bio-hybrid

A microchip to build a first-ever artificial kidney

Vanderbilt University Medical Center nephrologist and associate professor of medicine Dr. William H. Fissell IV, is making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient’s own heart.

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Cancer cells poised for growth when opportunity knocks

Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.

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News • Immunotherapy

The new frontier of cancer therapy

Healthcare, the world’s largest industry, is more than three times the size and value of the financial services sector, and is transforming faster than ever before, driving humanity to rethink the way we approach our health.

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News • Cell therapy

Using skin to save the heart

Following a heart attack or other heart trauma, the heart is unable to replace its dead cells. Patients are often left with little option other than heart transplants, which are rarely available, or more recently cell therapies that transplant heart cells into the patient's heart.

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'Self-Sabotage' prevents immune protection against Malaria

Australian scientists have for the first time revealed how malaria parasites cause an inflammatory reaction that sabotages our body's ability to protect itself against the disease. The discovery opens up the possibility of improving new or existing malaria vaccines by boosting key immune cells needed for long-lasting immunity. This could even include vaccines that have previously been ineffective…

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News • Biogel

Intelligent gel attacks cancer

A new injectable “biogel” is effective in delivering anti-cancer agents directly into cancerous tumours and killing them. This technology, developed by researchers at the University of Montreal Hospital Research Centre (CRCHUM), has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionize treatment for many forms of cancer.

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News • Study

A biomarker for multiple sclerosis

Patients with multiple sclerosis often receive a "hit and miss" treatment when the disease breaks out. A blood analysis is now for the first time able to reveal which of the two most important first-line drugs is better suited for which patients.

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Sugar-coated nanoworms not for breakfast in human immune system

Iron nanoparticles injected before magnetic resonance imaging can make tissues more visible and the same nanoparticles may allow doctors to precisely target tumors with new medicines. However, among the challenges to the practical use of nanoparticles in the human body is what scientists refer to as lack of “hemocompatibility” – nanoparticles tend to be attacked and cleared by the immune…

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News • Synthetic biology

Timing is everything in cells

Everyone who has played in a band or orchestra knows that playing in time creates music, while playing out of time creates cacophony. In an orchestra, each player may be out of tune when warming up, but eventually, all players must reach the same pitch, rhythm, and timing to produce a viable piece of music.

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