News • Trauma imaging
Suspected child abuse: Whole-spine MRI warranted
According to new research, whole-spine MRI commonly demonstrates isolated thoracolumbar injuries in children with suspected abusive head trauma.
Paediatrics
News • Widespread effects
Tougher childbirth in pandemic Europe
The COVID-19 pandemic has led to deficiencies and large inequalities in the care of mothers and newborns in Europe.
Article • Mass spec, qPCR and more
Newborn screening: early detection – new diagnostic possibilities
Since its introduction around 60 years ago, the screening of newborn babies for immune, hormone and metabolic disorders has prevented many people from experiencing severe disease progression. The scope of systematic early testing has been significantly enhanced through mass spectrometry (MS). In our interview, Professor Uta Ceglarek, one of the driving forces behind the introduction of MS…
News • DNA analysis
Should all babies have their genome sequenced at birth?
Genomics England, a government owned company, recently announced a pilot programme of whole genome sequencing to screen for genetic diseases in 200,000 healthy seeming newborns. But should every newborn baby have their whole genome sequenced? Experts debate the issue in The BMJ. Extensive clinical evidence has shown that screening for genetic diseases saves lives, and research has shown that it…
News • Incubator 2.0
Artificial uterus improves odds for preemies
“An artificial uterus – the incubator 2.0 – will become a reality within 10 years,” says Jasmijn Kok, one of the founders of Juno, a spin-off from the Eindhoven University of Technology, Netherlands. Together with researchers from the department of Industrial Design from the University, including her twin sister Lyla Kok, she wants to bring a technology that increases the chances of…
News • In children
Long COVID symptoms rarely persist beyond 12 weeks
Long COVID symptoms rarely persisted beyond 12 weeks in children and adolescents unlike adults.
News • Immune system research
How the gut microbiome can help prevent brain damage in preemies
Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.
News • More nurses, less ventilation and medication
A new approach to improve outcomes for critically-ill children
A major UK clinical trial led by Queen’s University Belfast has shown how a new approach to reduce the use of mechanical ventilation can greatly improve outcomes for critically ill infants and children. The study, funded by the National Institute for Health Research (NIHR) Health Technology Programme, found that a greater involvement of nurses, minimising sedation use and increasing daily…
News • VR app for children
Kids' fear of MRI: Let the penguins handle it
"You hear the noises, but they don't bother you at all": Since 2019, the “Pengunaut Trainer" has been preparing children for magnetic resonance imaging (MRI) examinations through role play. The app was developed under the leadership of the University Duisburg-Essen (UDE) and the Essen University Hospital (UK Essen).
News • Shot or not?
Covid vaccination for children: benefits and risks
The net benefit of vaccinating children is unclear, and vulnerable people worldwide should be prioritised instead, say experts in The BMJ today. But others argue that Covid-19 vaccines have been approved for some children and that children should not be disadvantaged because of policy choices that impede global vaccination.
News • Pediatric oncology cooperation
A royal visit for children with cancer
Queen Máxima of the Netherlands, after whom the Princess Máxima Center for Pediatric Oncology in Utrecht is named, along with several representatives of the center, the Hopp Children’s Cancer Center Heidelberg (KiTZ), University Hospital Heidelberg (UKHD) and the German Cancer Research Center (DKFZ), signed a memorandum on strategic cooperation in the field of pediatric oncology in Europe at…
News • Paediatrics
Vaccination helps protect unvaccinated from COVID-19
Higher levels of vaccination against COVID-19 were associated with lower rates of infection with SARS-CoV-2 among a group of unvaccinated people of 16 years of age and under.
News • Cardiology
On the way to better analysis of paediatric ECGs
Physicians are increasingly using software to automatically evaluate Holter ECG signals in adult patients, but so far, no software has been developed for children. Cardiomatics and the Medical University of Warsaw are on the way to a breakthrough in paediatric cardiology. They are developing an international tool for automatic assessment, analysis, and interpretation of electrocardiographic…
News • Medication issues
Finding better ways to determine safe drug doses for children
Determining safe yet effective drug dosages for children is an ongoing challenge for pharmaceutical companies and medical doctors alike. To make drugs and their development safer for children, researchers at Aalto University and the pharmaceutical company Novartis have developed a method that makes better use of available data.
News • Photonics21
Infrared scanner spots brain damage in babies early
A new photonics device currently in development aims to reduce unnecessary disabilities by improving the instant, real-time monitoring of newborn babies with harmless light particles.
News • Reducing hospital-related stress and anxiety
Website helps children and parents to prepare for hospitalization
Every year, millions of children around the world are admitted to hospital for having anaesthesia and surgery. Many of them experience preoperative anxiety which negatively affects both their hospital experience and medical outcome, as well as their future relationships with healthcare services from both a short-term and long-term point of view. A new, internationally aimed website offers…
News • Léopold Griffuel Award
Childhood cancer research: Award for Stefan Pfister
Stefan Pfister, a director of the Hopp Children’s Cancer Center Heidelberg (KiTZ), a department head at the German Cancer Research Center (DKFZ) and a pediatric oncologist at University Hospital Heidelberg (UKHD), has received the Léopold Griffuel Award from Fondation ARC, the French cancer research foundation. The prize, worth EUR 150,000 in Basic Research category, is one of the highest…
Video • Perinatal imaging
Fetal MRI precisely defines and detects abnormalities in unborn babies
MRI scanning can more precisely define and detect head, neck, thoracic, abdominal and spinal malformations in unborn babies, finds a large multidisciplinary study led by King’s College London with Evelina London Children’s Hospital, Great Ormond Street Hospital and University College London (UCL). In the study, published in Lancet Child and Adolescent Health, the team of researchers and…
News • Alarm system 'ELISE'
A digital 'co-pilot' for paediatric intensive care
Working in intensive care units poses special challenges for healthcare workers. They have to safely and reliably detect whether the condition of their seriously ill patients is deteriorating in a life-threatening way, and they have to do so under great time pressure because every minute counts. The stress level increases even more when the patients are children and adolescents. In paediatric…
News • Malignant paediatric cancer
Neuroblastoma: sending tumour cells on a collision course
With two commercially available inhibitors, the cell cycle of the cancer cells in neuroblastomas can be disrupted at a key point causing tumour cell death. Neuroblastomas are malignant solid tumours that occur mainly in early childhood. Inhibiting the MYCN oncogene or its function could be a promising therapeutic opportunity.
News • Coronavirus risk assessment
Investigating the risk of severe Covid-19 in children
So far, little research has been done on the risk of children being seriously affected by Covid-19 when the schools were open. A study from Karolinska Institutet has now shown that one child in 130,000 was treated in an intensive care unit on account of Covid-19 during the period March-June. The study has been published in New England Journal of Medicine.
News • Scattering suppression for imaging
'Autocorrect' feature to make X-rays safer for children
Clinicians will be able to take a low radiation, digital X-ray image - without the need for an anti-scatter grid - thanks to new innovative ‘scattering suppression software’. Developed by photonics scientists at the Warsaw University of Technology (WUT), working in collaboration with innovation incubator ACTPHAST 4.0 and medical imaging company Italray SRL, the new algorithm ‘auto…
News • Childhood cancer
Molecular super-enhancers determine progression of neuroblastomas
Childhood neuroblastomas display extreme differences in the way they develop: they can shrink spontaneously or spread aggressively to healthy tissue. It is molecular super-enhancers that activate the regulatory circuits that steer the tumor down one path or the other. These are the findings of research conducted by scientists from the Hopp Children's Cancer Center Heidelberg (KiTZ), the German…
Article • Distinguishing arteriopathies
Deterring paediatric acute stroke
Acute stroke in children has the same incidence as brain tumours and can seriously affect a patient’s life. Two kinds of arteriopathies are common drivers of paediatric acute stroke and radiologists must learn to distinguish their signs as early as possible to improve prognosis, according to Béatrice Husson, a paediatric radiologist at Le Kremlin Bicêtre Hospital in Paris.
News • Re-starting economy
Tackling ‘last mile’ of vaccine journey
Re-starting the global economy for billions of people will depend on successfully overcoming logistical challenges in the ‘last mile’ of a COVID-19 vaccine’s journey to immunisation stations, according to a new report.