The clinical performance of Beckman Coulter's high-sensitivity troponin I (hsTnI) assay Access hsTnI has been validated in a study. Within 2 hours, the assay delivers an accurate assessment of patients with suspected acute coronary syndrome (ACS).
A catheter based procedure to close a type of ‘hole in the heart’ followed by antiplatelet drugs (e.g. aspirin) should be recommended for patients under 60 years old, who have also had a stroke, say a panel of experts in The BMJ today. The procedure involves slowly moving a catheter into the heart to close the hole. Most guidelines currently advise against the closure procedure and instead…
A new software to calculate the pressure drop and vFFR value (vessel Fractional Flow Reserve) in the coronary artery non-invasively was presented to interventional cardiovascular experts at EuroPCR 2018 in Paris. The software called CAAS vFFR (Cardiovascular Angiographic Analysis Systems for vessel Fractional Flow Reserve) was developed by Pie Medical Imaging (Esaote Group). The vFFR calculation…
2018 European Society of Cardiology (ESC) and European Society of Hypertension (ESH) Joint Guidelines for the Management of Arterial Hypertension. A first look at the new European Guidelines for the treatment of high blood pressure was presented at the European Society of Hypertension meeting in Barcelona on June 9th 2018. These long-awaited guidelines have been jointly developed by clinicians…
Clinical trial enrolment favours men, according to a study presented at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress.1 The study found that fewer women meet eligibility criteria for trials of heart failure medication. Helena Norberg, author of the study, junior lecturer and PhD student, Umeå University, Sweden, said: “One of the…
Triggers of acute heart failure vary globally, according to late breaking results from the REPORT-HF registry presented at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. REPORT-HF is a global, prospective registry comparing regional differences in causes of acute heart failure, therapies, time to treatment, and outcomes. Professor Sean…
According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub. The research found that soaking in a hot tub several times per week for two months results in improved measures of cardiovascular health, beneficial changes in fat tissue and other improvements…
Patients’ own immune response has the potential to prevent the development and progression of heart failure, according to research presented at Frontiers in CardioVascular Biology (FCVB) 2018, a European Society of Cardiology congress. The study found antibodies in the plasma and heart muscle of end-stage heart failure patients. “The role of the immune response in the development of heart…
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers at the Cincinnati Children’s Heart Institute report in the journal Circulation testing a manufactured peptide called pUR4 to block the fibronectin protein in human…
The heart is capable of terminating arrhythmias itself after local gene therapy, potentially avoiding the need for patients to undergo painful electric shocks, according to a proof-of-concept study presented today at EHRA 2018, a European Society of Cardiology congress. Atrial fibrillation is the most common heart rhythm disorder (arrhythmia). Treatment aims to restore the heart’s normal rhythm…
The idea that it might be possible to be overweight or obese but not at increased risk of heart disease, otherwise known as the “obesity paradox”, has been challenged by a study of nearly 300,000 people published in in the European Heart Journal.
An Italian law requiring citizens to hold a certificate to use a defibrillator must change to improve survival from cardiac arrest, researchers argued today at Acute Cardiovascular Care 2018, a European Society of Cardiology congress. “Automated external defibrillator (AED) use before the arrival of the emergency medical services (EMS) plays a key role in improving victim survival from…
Google AI has made a breakthrough: successfully predicting cardiovascular problems such as heart attacks and strokes simply from images of the retina, with no blood draws or other tests necessary. This is a big step forward scientifically, Google AI officials said, because it is not imitating an existing diagnostic but rather using machine learning to uncover a surprising new way to predict these…
Geometry is often referenced for matters of the heart. Marriage has been described as “two parallel lines,” and others have compared love to an “irrational equation” or as unending as “pi.” But when it comes to the medical matters of the heart, geometry can be a lonely and dangerous affair. “The shape and size of a heart is not the same for every person, and a diseased heart, such…
Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels. Published in the journal Nature Medicine, the UCLA-led study in mice found that MeXis controls the expression of a protein that pumps cholesterol out…
Loyola Medicine is the first academic medical center in Illinois to use the TCAR system, which reduces stroke risk during carotid artery procedures by temporarily reversing blood flow. Carotid arteries on each side of the neck supply blood to the brain. In patients with carotid artery disease, a build-up of plaque can cause blockages. A common method to open the artery involves a balloon…
Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I study is part of a multi-center collaboration dedicated to employing innovative therapies to improve outcomes for children…
Standard medical tests miss nearly two-thirds of heart attack diagnoses, reveals research presented at CMR 2018. “Unrecognised MI has a poor short-term prognosis but until now the long-term outlook was unknown,” said lead author Dr Tushar Acharya, a cardiologist at the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, US. “This study investigated long-term…
Macrophage cells routinely remove dead or dying cells to maintain the body homeostasis. Such removal becomes crucial after serious injury, especially the repair of dead heart muscle after a heart attack. University of Alabama at Birmingham researchers have preliminary data, with cultured cells or diabetic hearts, that diabetes impairs this removal of dead heart-muscle cells. They believe this…
Nearly a quarter of patients with chronic ischaemic cardiovascular disease are dead or hospitalised within six months, reports a European Society of Cardiology (ESC) study published in the European Journal of Preventive Cardiology. “Coronary artery disease is the leading cause of death worldwide yet some patients appear to get lost in the system after their initial visit to a hospital or…
Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy — aimed directly at the heart — can be used to treat patients with a life-threatening heart rhythm. They treated five patients who had irregular heart rhythms, called ventricular tachycardia, at the School of Medicine. The patients…
By no means are only elderly people at risk from heart diseases. Physically active individuals can also be affected, for example if a seemingly harmless flu bug spreads to the heart muscle. Should this remain undetected and if, for example, a builder continues with his strenuous job or an athlete carries on training, this can lead to chronic inflammation and in the worst case even to sudden…
Coordinating the response to heart attacks among emergency responders and hospitals reduces the time to treatment and saves lives - even on a large, regional scale, according to a study led by the Duke Clinical Research Institute with support from the American Heart Association. In the largest demonstration of the coordinated approach - 132 hospitals and 946 EMS agencies in 12 U.S. regions -…
If you have a heart attack or stroke, it’s important to get your “bad” cholesterol measured by your doctor on a follow up visit. Researchers have found that one step is significantly associated with a reduced risk of suffering another serious cardiovascular episode. The new research, conducted by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City, found that…
A new blood test to detect heart attacks has been developed by a team of researchers at King’s College, London, which could speed up diagnosis, according to results from pan-European trials. The test is quicker than the standard test, which combines an ECG with a blood test to measure the levels of troponin. Under current guidelines, suspected heart attack cases are tested for high blood…
