Chemotherapy

Article • Five-year EU project to avoid heart damage in oncology patients

Cardiac collaterals in breast cancer therapy

Modern cancer therapies are tough on the tumours, but often, also on the heart of the patients. The “CARDIOCARE” project aims to reduce the cardiac burden of anti-cancer therapies through more patient-tailored treatment approaches. At the ESC cardiology congress, Professor Katerina Naka from the project’s consortium explained why older patients are at the highest risk of cardiotoxic…

News • Injury of non-cancer cells identified as trigger

Breast cancer recurrence: Could chemotherapy cause what it's trying to stop?

Chemotherapy can be an effective means to fight breast cancer, but under certain circumstances, the treatment can cause dormant cancer cells to re-awaken, new research finds.

News • Proof-of-concept research

Researchers reverse chemotherapy-related fertility loss

A new study by investigators from Brigham and Women’s Hospital demonstrates the potential for restoring fertility when the ovaries have stopped working.

News • Oncology & Biomedical Technology

New treatment option in bone cancer: gene therapy combined with chemotherapy

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.

News • Cancer treatment for older patients

Head and neck cancer in older patients: Increasing the chance of survival

Should patients over the age of 70 with head and neck cancer receive aggressive combined radiotherapy and chemotherapy? This is a controversial issue among patients, their families and health professionals.

News • Chemotherapy, testicular cancer

Gene scissors find target for testicular cancer therapy

Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors: Cisplatin is used successfully in the chemotherapy of testicular cancer.

News • Protein controls resistance

Targeted approach holds promise to improve chemotherapy

Chemotherapy resistance is a main cause of treatment failure and death in cancer patients. Researchers from Brussels found how cancer cells protect themselves from the aggressive treatment.

News • Randomness as resistance strategy

Cancer response to chemotherapy: a game of chance?

Cancer cells have an innate randomness in their ability to respond to chemotherapy, which is another tool in their arsenal of resisting treatment, new research shows.

News • Making tumours susceptible to chemo

Breast cancer: target protein may hold key to therapy success

A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research.

News • Trial finds improved survival rates

Pancreatic cancer: chemotherapy before surgery brings benefits

Treating pancreatic cancer patients with chemotherapy before surgery significantly improved 1-year survival rates compared to immediate surgery, a randomised clinical trial has found.

News • Glioblastoma treatment approach

'Zapping' brain cancer cells shows surprising benefits

Canadian researchers have developed a new method of killing brain cancer cells while preserving the tissue around it. A remarkable side-benefit: chemotherapy of the cancer suddenly becomes possible.

News • New treatment approach

Colon cancer: Overcoming chemotherapy resistance

Colorectal cancer is one of the most common cancers. A team from the University of Geneva has found an alternative for patients who have developed resistance to chemotherapy treatments.

News • New study

Can physical exercise enhance the effect of chemotherapy against breast cancer?

Many women diagnosed with breast cancer can be cured with surgery, radiotherapy and medical treatment. Swedish researchers explore whether physical exercise can support the anti-tumour effects.

Article • Cryotherapy substitute

The surprising applications of ice cream in healthcare

From treat to treatment: Polish researchers explore the medical benefits of ice cream – despite the semi-serious presentation, a topic with surprising relevance for patients undergoing chemotherapy.

News • Relapse rate research

Breast cancer: Fertility preservation measures do not increase recurrence risk

A new study shows that women with a breast cancer diagnosis undergoing procedures for fertility preservation are not at increased risk of recurrence of the disease or disease-specific mortality.

News • CMR-ECV vs. light-chain cardiac amyloidosis

'Stiff heart syndrome': Advanced MRI benefits patients

An advanced form of cardiac MRI has for the first-time enabled clinicians to measure the effectiveness of chemotherapy in patients with the life-limiting condition ‘stiff heart syndrome’.

News • Companion treatment

Magnetic therapy to enhance breast cancer chemotherapy

A team of researchers from Singapore has developed a novel magnetic therapy that serves as an effective companion therapy to chemotherapy to enhance treatment outcome for breast cancer.

News • Cancer therapy side-effects

Researchers investigate link between chemotherapy and infertility

In order to better prevent and restore fertility and reduce the risk of sterility in cancer survivors, researchers investigate the mechanisms behind negative effects of chemotherapy.

News • Cancer research

Origins of metastasis unraveled

For a long time, the origin of metastasis remained obscure. Now, scientists have discovered some of the mechanisms these cells arise.

News • Bone marrow transplant

The impact of chemotherapy on the brain

Pre-transplant chemotherapy facilitates the replacement of the brain's innate immune cells, by other immune cells derived from the transplanted stem cells.

News • Cancer therapy

Chemo after breast cancer surgery? Gene expression test to help decision

Physicists from Leipzig University have developed gene expression tests to examine whether additional chemotherapy is necessary and really effective after breast cancer surgery.

News • Chemotherapy approach

New receptor insights might leave cancer bitter

Bitter taste receptors do not only support humans in tasting. They are also found on cancer cells. A team led by Veronika Somoza from the Faculty of Chemistry at the University of Vienna and the German Leibniz Institute for Food Systems Biology at the Technical University of Munich has investigated the role they play there. For this purpose, the scientists compiled and evaluated extensive…

Article • Cancer research

Prostate cancer: Blood tests predict chemotherapy resistance

Researchers have found that regular blood tests can help detect whether prostate cancer patients have resistance to drugs treating the condition. The findings were presented at the National Cancer Research Institute (NCRI) virtual Festival.

News • Ductal adenocarcinoma

Pancreatic cancer ‘priming’ may make chemotherapy more effective

A new approach to ‘prime’ the tumour environment may improve how effective chemotherapy is for pancreatic ductal adenocarcinoma, one of the most aggressive forms of pancreatic cancer. In preclinical models, a team at the Garvan Institute of Medical Research could enhance the tumours’ response to chemotherapy by reducing the stiffness and density of the connective tissue known as the stroma,…

News • DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…

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